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Accutane (isotretinoin) Drug Interactions

A total of 127 drugs are known to interact with Accutane (isotretinoin).

  • 21 major drug interactions
  • 106 moderate drug interactions

Show all medications in the database that may interact with Accutane (isotretinoin).

Check for interactions

Type in a drug name to check for interactions with Accutane (isotretinoin).

Most frequently checked interactions

View interaction reports for Accutane (isotretinoin) and the medicines listed below.

  • Abilify (aripiprazole)
  • Adderall (amphetamine / dextroamphetamine)
  • Ambien (zolpidem)
  • amoxicillin (Amoxil, Trimox, Apo-Amoxi, Amoxicot, Moxatag, DisperMox, Biomox, Wymox, Moxilin)
  • biotin (Hair, Skin & Nails, Appearex)
  • doxycycline (Vibramycin, Oracea, Doxy 100, Monodox, Doryx, Targadox, Vibra-Tabs, Adoxa, Acticlate, Morgidox, Periostat, Doxy-Caps, Uracil, Adoxa TT, Mondoxyne NL, Doxy 200, Doxy-D, Oraxyl, Alodox, Adoxa Pak, Avidoxy, Adoxa CK, Ocudox, LymePak, NicAzel Doxy, Doxy-Lemmon, Doryx MPC)
  • fluoxetine (Prozac, Prozac Weekly, Sarafem, Selfemra, Rapiflux)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Motrin IB, Proprinal, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Motrin Childrens, Rufen, Ibuprofen PMR, Ibu-8, Motrin Pediatric, Menadol, Nuprin, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, NeoProfen, Ibu-Tab, Genpril, Haltran, IBU-200, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Lamictal (lamotrigine)
  • Lexapro (escitalopram)
  • melatonin (Melatonin Time Release, SGard, Bio-Melatonin, Health Aid Melatonin, VesPro Melatonin)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • minocycline (Minocin, Solodyn, Dynacin, Ximino, Minocin for Injection, Myrac, Cleeravue-M, Minolira)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • phentermine (Adipex-P, Lomaira, Fastin, Suprenza, Ionamin, Teramine, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Oby-Cap, Phentride, Obephen, Panshape M, Pro-Fast SR, T-Diet, Zantryl, Oby-Trim, Pro-Fast SA, Teramine ER)
  • Prozac (fluoxetine)
  • spironolactone (Aldactone, CaroSpir)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vitamin D3 (cholecalciferol)
  • Vitamins (multivitamin)
  • Vyvanse (lisdexamfetamine)
  • Xanax (alprazolam)
  • Zoloft (sertraline)
  • Zyrtec (cetirizine)

Accutane (isotretinoin) alcohol/food interactions

There are 3 alcohol/food interactions with Accutane (isotretinoin)

Accutane (isotretinoin) disease interactions

There are 5 disease interactions with Accutane (isotretinoin) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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