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Potassium-sparing diuretics

Other names: Potassium sparing diuretics

What are Potassium-sparing diuretics

Potassium-sparing diuretics are medicines that increase diuresis (urination) without the loss of potassium. They are generally weak diuretics and work by interfering with the sodium-potassium exchange in the distal convoluted tubule of the kidneys or as an antagonist at the aldosterone receptor. Aldosterone promotes the retention of sodium and water, so if potassium-sparing diuretics are used to block this effect, more sodium and water can pass into the collecting ducts of the kidneys, increasing diuresis.

Because potassium-sparing diuretics do not promote the secretion of potassium during diuresis they do not cause hypokalemia (low potassium levels). However, there is a risk of hyperkalemia (high potassium levels) if they are used with other agents that also retain potassium, such as ACE inhibitors.

Potassium-sparing diuretics may be used alone or in conjunction with loop or thiazide diuretics.

List of Potassium-sparing diuretics:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
Inspra (Pro, More...)
generic name: eplerenone
1 review
   
10
Dyrenium (Pro, More...)
generic name: triamterene
1 review
   
8.0
Aldactone (Pro, More...)
generic name: spironolactone
16 reviews
   
7.0
Midamor (Pro, More...)
generic name: amiloride
1 review
   
3.5
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