Eplerenone User Reviews & Ratings

• Daw...
• Taken for 6 months to 1 year
• April 13, 2024

For High Blood Pressure "I have tried every class of blood pressure medicine in all the years from when I was 38 until last year when I was 76! After all this time, they incidentally found an adenoma on one of my kidneys, which can cause high blood pressure. I started on this medicine last December and thought it would not work. It took 2 months, but alas, I saw readings in the 120s/70s. I was shocked. Then here we are in 2025 and it came back again, readings in the 190s/100s. I was only taking 25mg a day. The nephrologist increased it to 75. It is working. I will say that I have no energy at all. I never thought it was this medicine, but I am convinced it saps your energy. Sooner or later, I will need the laparoscopic surgery to remove the adenoma, but until then, they try to control it with meds. Hope this helps someone who has high blood pressure."

• Anonymous
• Taken for 6 months to 1 year
• March 12, 2023

For High Blood Pressure "3/12/23 After taking eplerenone 25 mg for approximately two months for hypertension, I started experiencing extreme stomach pain, excessive night sweating, chills with no tolerance to cold, whether in hot, warm, or cold environments, and hearing/feeling pulsating in my ears, sometimes heart racing. While taking the 25 mg, blood pressure decreased from 175 systolic to between 130-140 systolic. Diastolic remained between 80-70 or less. When the doctor increased the dosage to 50 mg, the above intolerances became worse and blood pressure started fluctuating between 160/82 to 150/79 to 125/65. But the side effects are intolerable."

• Jim...
• Taken for 1 to 6 months
• July 2, 2019

For High Blood Pressure "I did not tolerate this drug very well. I changed from spironolactone, which gave me severe nipple pain. Eplerenone at 25 mg was well tolerated but had minimal effect. Doctor increased the dose to 50 mg, and that started a general malaise with uncomfortable breast pain and also made my urine extremely odorous and acidic, which triggered urinary tract sensitivity and burning. I thought I had a UTI, but symptoms disappeared when I stopped taking the drug. I think I’ll live with my slightly elevated blood pressure, thank you."

• Anonymous
• Taken for less than 1 month
• August 12, 2012

For High Blood Pressure "I have had problems with low potassium for over a year, so the blood pressure goes up because of it. Tried spironolactone, but side effects were bad, especially migraines. I started on 50mg of eplerenone, but the side effects of extreme fatigue, dry mouth, muscle weakness, and getting dehydrated very easily caused me to go down to 25mg to see if it's any better. My potassium went from 3.1 to 3.8 in 6 days on this, but those 6 days were exhausting. So, it's definitely good for that. Not sure if I can stick it out with feeling so bad on it. Tried many others and supplements plus foods and never got higher than 3.1. It's the aldosterone that causes high blood pressure and low potassium. Hope more people join in on their experience."

• Lad...
• Taken for less than 1 month
• January 8, 2020

For High Blood Pressure "I took one eplerenone 25 mg tablet. I could hardly get any urine out. I reported to the doctor who said that was normal. My blood pressure 6 hours after taking the one dose was 210/106. I looked eplerenone up and found that it can cause high blood pressure as aldosterone increases the amount of sodium and water a person retains. I could barely urinate, so I retained a lot of sodium and water. I stopped taking this after the one dose. I cannot take a chance on a stroke or heart attack or heart failure. I will start exercising to get rid of adrenaline."

• kEI...
• Taken for 1 to 6 months
• December 17, 2021

Inspra (eplerenone) for Heart Failure "I was prescribed Inspra when valsartan caused very low BP. I was also taking a low dose of beta-blockers. Unfortunately, Inspra had the same effect. It would help if these drugs were available in combined forms, starting at very low doses in order to minimize non-compliance among patients who experience troubling side effects. Inspra did not have any noticeable symptomatic benefits, but the low BP was very unacceptable."

• Sim...
• Taken for 1 to 6 months
• August 3, 2021

For High Blood Pressure "Started taking this. I now have bouts of coughing leading to breathlessness. This happens when resting and when exercising. Taking with lots of other meds, two in particular are Bisoprolol and Furosemide. When suggesting to a medical professional that the cough might be due to the eplerenone, I was informed they had never heard of this affecting anyone in that way before. I am seeking further advice as the cough is not improving. Originally just given Bisoprolol, which improved my condition. Then added the eplerenone, which has had a negative effect on how I feel. But I will seek further advice before stopping, as advised on the patient leaflet."

• jam...
• December 8, 2013

For High Blood Pressure "Was on spironolactone for 5 years with terrible side effects, name it, I had it. The breast soreness is what did it for me, and finally, I stumbled into eplerenone after 5 years of suffering through spironolactone. Eplerenone works great for me with minimum or no side effects, and the most important thing is that there is no more breast pain. My blood pressure is under control and my potassium is 4.5. I incorporated a workout schedule with this medication 2-4 times a week."

• Ela...
• Taken for less than 1 month
• March 30, 2023

For Heart Failure "I started eating for my blood type. Exercising a bit more. Staying hydrated. Cut way back on smoking, 5 cigarettes not 15/day. Rare minimal alcohol. I was eating very healthy, but with my blood type, cabbage, cauliflower, Brussels sprouts, avocados, and oranges are all harmful to my health! Who would have thought? Cutting out all the healthy harmful foods has made a tremendous difference in how I feel. The other slight changes may have made a difference, but the food changes were the key to my health. My doctor is amazed and happy with the results. Only took this pill a few days. It was awful. That’s when I ran across Eating for your blood type."

• Rox...
• Taken for 2 to 5 years
• October 17, 2023

For High Blood Pressure "After one year of suffering with uncontrollable blood pressure, I was put on Eplerenone 25mg, which worked well for me. I have been on it for four years now with no side effects."

• Hyp...
• Taken for 1 to 2 years
• October 30, 2020

For Heart Failure "On this eplerenone tablet for over a year, I have side effect symptoms of severe cough, throat swelling, muscle pain, chest pain, very bad fatigue, and flu-like symptoms."

• Jra...
• August 16, 2020

For High Blood Pressure "Excessive sweating; numbness in feet and fingers; taken with Lisinopril."

• Ban...
• June 20, 2014

For High Blood Pressure "Reduced my blood pressure well, but experienced extreme tiredness. A routine blood test found hyperkalemia and reduced renal function, requiring three days in the hospital for treatment."

• sea...
• September 10, 2014

Inspra (eplerenone) for High Blood Pressure "Life is the same again!"