Generic Name: eplerenone (ep LER e none)
Brand Name: Inspra
Medically reviewed on July 12, 2018
What is Inspra?
Inspra blocks the actions of the hormone aldosterone in the body. Aldosterone is important for the regulation of blood pressure.
Inspra may also be used for purposes not listed in this medication guide.
You may not be able to take Inspra if you have severe kidney disease, high potassium levels in your blood, or type 2 diabetes with increased levels of albumin (a protein) in your urine.
Serious drug interactions can occur when certain medicines are used together with Inspra. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
Before taking this medicine
You may not be able to take this medicine if you are allergic to Inspra, or if you have:
high potassium levels in your blood (hyperkalemia);
severe kidney disease; or
type 2 diabetes with increased levels of albumin (a protein) in your urine.
Some medicines can interact with Inspra and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:
To make sure Inspra is safe for you, tell your doctor if you have:
high cholesterol or triglycerides; or
if you take other heart or blood pressure medications.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether eplerenone passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
How should I take Inspra?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take Inspra in larger or smaller amounts or for longer than recommended.
Inspra may be taken with or without food.
While using Inspra, you may need blood tests, and your blood pressure will need to be checked often.
If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Inspra?
Do not use potassium supplements or salt substitutes while you are taking Inspra, unless your doctor has told you to.
This drug side effects
Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
little or no urination;
fast or uneven heartbeats;
swelling in your feet or lower legs;
high potassium--nausea, slow or unusual heart rate, weakness, loss of movement; or
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Inspra?
Many drugs can interact with Inspra, and some drugs should not be used together. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete and many other drugs can interact with Inspra. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 6.01.
More about Inspra (eplerenone)
- Inspra Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 1 Review
- Generic Availability
- Drug class: aldosterone receptor antagonists