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Medications for Skin and Structure Infection

Other names: Complicated Skin and Skin Structure Infection; cSSSI

What is Skin and Structure Infection:  Invasion of the skin or structure with organisms that have the potential to cause disease.

Medications to treat Skin and Structure Infection

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
mupirocin Rx B N 17 reviews
7.0

Generic name: mupirocin topical

Brand names:  Bactroban, Bactroban Nasal, Centany, Centany AT Kit

Drug class: topical antibiotics

For consumers: dosage, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Bactroban Rx B N 14 reviews
8.0

Generic name: mupirocin topical

Drug class: topical antibiotics

For consumers: dosage, side effects

For professionals: Prescribing Information

 
Augmentin Rx B N 4 reviews
6.0

Generic name: amoxicillin / clavulanate systemic

Drug class: beta-lactamase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Azithromycin Dose Pack Rx B N Add review Add

Generic name: azithromycin systemic

Drug class: macrolides

For consumers: dosage, interactions, side effects

 
amoxicillin / clavulanate Rx B N 10 reviews
6.0

Generic name: amoxicillin / clavulanate systemic

Brand names:  Augmentin, Augmentin XR, Amoclan, Augmentin ES-600

Drug class: beta-lactamase inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Zithromax Rx B N Add review Add

Generic name: azithromycin systemic

Drug class: macrolides

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Zyvox Rx C N 7 reviews
8.0

Generic name: linezolid systemic

Drug class: oxazolidinone antibiotics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
azithromycin Rx B N Add review Add

Generic name: azithromycin systemic

Brand names:  Azithromycin Dose Pack, Zithromax, Zmax

Drug class: macrolides

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
minocycline Rx D N 1 review
10

Generic name: minocycline systemic

Brand names:  Minocin, Dynacin, Myrac, Ximino

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Ceftin Rx B N Add review Add

Generic name: cefuroxime systemic

Drug class: second generation cephalosporins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Omnicef Rx B N Add review Add

Generic name: cefdinir systemic

Drug class: third generation cephalosporins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
gentamicin Rx N N Add review Add

Generic name: gentamicin topical

Drug class: topical antibiotics

For consumers: interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Biaxin Rx C N Add review Add

Generic name: clarithromycin systemic

Drug class: macrolides

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Avelox Rx C N 1 review
8.0

Generic name: moxifloxacin systemic

Drug class: quinolones

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
clarithromycin Rx C N 2 reviews
4.0

Generic name: clarithromycin systemic

Brand names:  Biaxin, Biaxin XL

Drug class: macrolides

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Duricef Rx B N Add review Add

Generic name: cefadroxil systemic

Drug class: first generation cephalosporins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Minocin Rx D N Add review Add

Generic name: minocycline systemic

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Augmentin XR Rx B N 1 review
9.0

Generic name: amoxicillin / clavulanate systemic

Drug class: beta-lactamase inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
cefdinir Rx B N 2 reviews
1.0

Generic name: cefdinir systemic

Brand names:  Omnicef, Omnicef Omni-Pac

Drug class: third generation cephalosporins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
cefuroxime Rx B N 1 review
1.0

Generic name: cefuroxime systemic

Brand names:  Ceftin, Zinacef

Drug class: second generation cephalosporins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Cipro Rx C N Add review Add

Generic name: ciprofloxacin systemic

Drug class: quinolones

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
ciprofloxacin Rx C N Add review Add

Generic name: ciprofloxacin systemic

Brand names:  Cipro, Cipro I.V., Cipro XR, Proquin XR

Drug class: quinolones

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Cipro I.V. Rx C N Add review Add

Generic name: ciprofloxacin systemic

Drug class: quinolones

For consumers: dosage, interactions, side effects

 
Cipro XR Rx C N Add review Add

Generic name: ciprofloxacin systemic

Drug class: quinolones

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Cubicin Rx B N 1 review
10

Generic name: daptomycin systemic

Drug class: miscellaneous antibiotics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
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Topics under Skin and Structure Infection

Alternative treatments for Skin and Structure Infection

The following products are considered to be alternative treatments or natural remedies for Skin and Structure Infection. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Skin and Structure Infection.

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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