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What type of drug is Nuzyra (omadacycline)?

Medically reviewed by Drugs.com Last updated on Nov 7, 2018.

Official Answer

by Drugs.com

Nuzyra (omadacycline) is an antibacterial tetracycline antibiotic.

Nuzyra is given either as an intravenous (IV) infusion or as a once-daily tablet taken by mouth.

  • Nuzyra is used to treat adult patients with community-acquired bacterial pneumonia (CABP) caused by susceptible microorganisms such as Streptococcus pneumoniae, Staphylococcus aureus, or Haemophilus influenzae.
  • It is also approved for treatment of acute bacterial skin and skin structure infections (ABSSSI).

How do Nuzyra side effects differ from other tetracyclines?
Nuzyra has similar warnings to other tetracycline-class antibacterial drugs such as:

  • permanent tooth discoloration (yellow-gray-brown) if used in the last half of pregnancy, infancy, and childhood up to the age of 8 years.
  • reversible inhibition of bone growth if used in the last half of pregnancy, infancy, and childhood up to the age of 8 years.
  • serious allergic reactions
  • development of C. difficile diarrhea
  • photosensitivity (sun allergy)
  • pseudotumor cerebri (pressure inside the skull increases)
  • anti-anabolic action (inhibits cell division and new tissue growth) which has led to increased blood urea nitrogen (BUN), azotemia, acidosis, hyperphosphatemia, pancreatitis, and abnormal liver function tests
  • discontinue Nuzyra and call your doctor if any of these side effects are suspected.

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