Macrolides
What are Macrolides
Macrolides are a class of antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), a type of soil-borne bacteria.
Macrolides inhibit protein synthesis in bacteria by reversibly binding to the P site of the 50S unit of the ribosome. Macrolides mainly affect gram-positive cocci and intracellular pathogens such as mycoplasma, chlamydia, and legionella. Erythromycin was the first macrolide discovered; other macrolides include azithromycin, clarithromycin, and roxithromycin.
Their action is primarily bacteriostatic but may be bactericidal at high concentrations, or depending on the type of microorganism.
List of Macrolides:
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Medical conditions associated with macrolides:
- Babesiosis
- Bacterial Endocarditis Prevention
- Bacterial Infection
- Bartonellosis
- Bowel Preparation
- Bronchitis
- Bullous Pemphigoid
- Campylobacter Gastroenteritis
- Cervicitis
- Chancroid
- Chlamydia Infection
- Clostridial Infection
- COPD, Acute
- Cystic Fibrosis
- Dental Abscess
- Follicular Lymphoma
- Gonococcal Infection, Uncomplicated
- Granuloma Inguinale
- Helicobacter Pylori Infection
- Legionella Pneumonia
- Lyme Disease
- Lyme Disease, Erythema Chronicum Migrans
- Lymphogranuloma Venereum
- Mycobacterium avium-intracellulare, Prophylaxis
- Mycobacterium avium-intracellulare, Treatment
- Mycoplasma Pneumonia
- Nongonococcal Urethritis
- Ocular Rosacea
- Otitis Media
- Pelvic Inflammatory Disease
- Pemphigoid
- Pertussis
- Pertussis Prophylaxis
- Pharyngitis
- Pneumonia
- Rheumatic Fever Prophylaxis
- Sinusitis
- Skin and Structure Infection
- Skin or Soft Tissue Infection
- STD Prophylaxis
- Strep Throat
- Streptococcal Infection
- Syphilis, Early
- Tonsillitis/Pharyngitis
- Toxoplasmosis
- Typhoid Fever
- Upper Respiratory Tract Infection
