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Medications for Clostridioides difficile Infection

Other names: C. diff; C. difficile; CDAD; CDI; Clostridial Infection; Clostridium difficile Infection; Clostridium difficile-Associated Diarrhea; Clostridium Infection

Infections with bacteria of the genus Clostridium, a group of anaerobic bacteria. They include, Clostridium difficile, Clostridium perfringens and Clostridium botulinum.

Drugs used to treat Clostridioides difficile Infection

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
vancomycin 6.4 13 reviews for vancomycin to treat Clostridioides difficile Infection
Rx C N
Generic name:
vancomycin systemic
Brand names:
Vancocin, Firvanq, Vancocin HCl, Vancocin HCl Pulvules
Drug class:
glycopeptide antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Flagyl 7.0 6 reviews for Flagyl to treat Clostridioides difficile Infection
Rx B N X
Generic name:
metronidazole systemic
Drug class:
amebicides, miscellaneous antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
metronidazole 4.5 49 reviews for metronidazole to treat Clostridioides difficile Infection
Rx B N X
Generic name:
metronidazole systemic
Brand names:
Flagyl, Flagyl IV, Flagyl 375, Likmez
Drug class:
amebicides, miscellaneous antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dificid 7.1 15 reviews for Dificid to treat Clostridioides difficile Infection
Rx B N
Generic name:
fidaxomicin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
fidaxomicin 7.4 18 reviews for fidaxomicin to treat Clostridioides difficile Infection
Rx B N
Generic name:
fidaxomicin systemic
Brand name:
Dificid
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Vancocin Rate Add review
Rx C N
Generic name:
vancomycin systemic
Drug class:
glycopeptide antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Firvanq Rate Add review
Rx C N
Generic name:
vancomycin systemic
Drug class:
glycopeptide antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Flagyl IV Rate Add review
Rx B N X
Generic name:
metronidazole systemic
Drug class:
amebicides, miscellaneous antibiotics
For consumers:
dosage, interactions, side effects
Flagyl 375 Rate Add review
Rx B N X
Generic name:
metronidazole systemic
Drug class:
amebicides, miscellaneous antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vancocin HCl Rate Add review
Rx C N
Generic name:
vancomycin systemic
Drug class:
glycopeptide antibiotics
For consumers:
dosage, interactions, side effects
Likmez Rate Add review
Rx B N X
Generic name:
metronidazole systemic
Drug class:
amebicides, miscellaneous antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Penicillin VK Rate Add review
Rx B N
Generic name:
penicillin v potassium systemic
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Pfizerpen Rate Add review
Rx B N
Generic name:
penicillin g potassium systemic
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vancocin HCl Pulvules Rate Add review
Rx C N
Generic name:
vancomycin systemic
Drug class:
glycopeptide antibiotics
For consumers:
dosage, interactions, side effects
penicillin g potassium Rate Add review
Rx B N
Generic name:
penicillin g potassium systemic
Brand name:
Pfizerpen
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
penicillin g sodium Rate Add review
Rx B N
Generic name:
penicillin g sodium systemic
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
penicillin v potassium Rate Add review
Rx B N
Generic name:
penicillin v potassium systemic
Brand name:
Penicillin VK
Drug class:
natural penicillins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information

Frequently asked questions

View more FAQ

Topics under Clostridioides difficile Infection

Alternative treatments for Clostridioides difficile Infection

The following products are considered to be alternative treatments or natural remedies for Clostridioides difficile Infection. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Clostridioides difficile Infection.

Learn more about Clostridioides difficile Infection

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.