Skip to Content

Flagyl (metronidazole) Drug Interactions

A total of 403 drugs are known to interact with Flagyl (metronidazole).

  • 8 major drug interactions
  • 189 moderate drug interactions
  • 206 minor drug interactions

Show all medications in the database that may interact with Flagyl (metronidazole).

Check for interactions

Type in a drug name to check for interactions with Flagyl (metronidazole).

Most frequently checked interactions

View interaction reports for Flagyl (metronidazole) and the medicines listed below.

  • amoxicillin (Amoxil, Trimox, Apo-Amoxi, Amoxicot, Moxatag, DisperMox, Moxilin, Wymox, Biomox)
  • aspirin (Aspir 81, Ecotrin, Aspirin Low Strength, Acetylsalicylic Acid, Bayer Aspirin, Aspir-Low, Bufferin, Ascriptin, Arthritis Pain, Aspiritab, Aspergum, Fasprin, Halfprin, Easprin, Ecotrin Adult Low Strength, Empirin, Migralex, Aspi-Cor, St. Joseph 81 mg Chewable Aspirin, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Ecotrin Maximum Strength, Entercote, Bufferin Extra Strength, Ascriptin Enteric, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspirtab, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, St. Joseph Aspirin, Stanback Analgesic, Norwich Aspirin, Acuprin 81, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Aspirin Lite Coat, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Augmentin (amoxicillin / clavulanate)
  • Bactrim (sulfamethoxazole / trimethoprim)
  • cephalexin (Keflex, Keftab, Daxbia, Biocef, Zartan, Panixine)
  • Cipro (ciprofloxacin)
  • ciprofloxacin (Cipro, Cipro XR, Cipro I.V., Cipro Cystitis Pack, Proquin XR)
  • Diflucan (fluconazole)
  • doxycycline (Vibramycin, Oracea, Monodox, Doxy 100, Doryx, Adoxa, Targadox, Morgidox, Acticlate, Vibra-Tabs, Doxy-Caps, Periostat, Doxy 200, Oraxyl, Doryx MPC, Doxy-D, Alodox, Adoxa Pak, Avidoxy, Adoxa TT, Adoxa CK, Ocudox, LymePak, Uracil, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Lasix (furosemide)
  • Levaquin (levofloxacin)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Macrobid (nitrofurantoin)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, RoxyBond, Percolone, Oxecta, Oxydose, Oxyfast, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol, Dazidox)
  • Percocet (acetaminophen / oxycodone)
  • phentermine (Adipex-P, Lomaira, Fastin, Ionamin, T-Diet, Suprenza, Oby-Cap, Teramine, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Phentride, Obephen, Panshape M, Pro-Fast SR, Zantryl, Oby-Trim, Pro-Fast SA, Teramine ER)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Sterapred DS, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • Tylenol (acetaminophen)
  • Valtrex (valacyclovir)
  • Vitamin D3 (cholecalciferol)
  • wine
  • Xanax (alprazolam)
  • Zofran (ondansetron)
  • Zyrtec (cetirizine)

Flagyl (metronidazole) alcohol/food interactions

There are 2 alcohol/food interactions with Flagyl (metronidazole)

Flagyl (metronidazole) disease interactions

There are 7 disease interactions with Flagyl (metronidazole) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide