Generic Name: dalbavancin (DAL ba VAN sin)
Brand Name: Dalvance
What is dalbavancin?
Dalbavancin is an antibiotic that fights bacteria.
Dalbavancin is used to treat severe skin infections caused by bacteria.
Dalbavancin may also be used for purposes not listed in this medication guide.
What is the most important information I should know about dalbavancin?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my healthcare provider before using dalbavancin?
You should not use dalbavancin if you are allergic to it.
To make sure dalbavancin is safe for you, tell your doctor if you have:
liver disease; or
an allergy to other antibiotics such as vancomycin or telavancin.
FDA pregnancy category C. It is not known whether dalbavancin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether dalbavancin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How is dalbavancin given?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Dalbavancin is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Dalbavancin is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Do not shake the mixed medicine or it may foam. The mixture should appear clear or slightly yellow. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.
After mixing, store in the refrigerator or at room temperature. Do not freeze. Use the medicine within 48 hours after mixing.
Dalbavancin is usually given in two doses, one week apart. Each IV infusion will take at least 30 minutes to complete.
Injecting this medicine too quickly can cause you to feel warm, itchy, anxious, or light-headed.
Each single-use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left over after injecting your dose.
Use a disposable needle only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Dalbavancin will not treat a viral infection such as the flu or a common cold.
Store unmixed dalbavancin powder at room temperature away from moisture and heat.
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose of dalbavancin.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving dalbavancin?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using dalbavancin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Dalbavancin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
diarrhea that is watery or bloody.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Dalbavancin dosing information
Usual Adult Dose for Skin and Structure Infection:
1000 mg IV, followed one week later by 500 mg IV
Comments: Infuse over 30 minutes.
Uses: Treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of the following Gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), Streptococcus pyogenes, Streptococcus agalactiae and Streptococcus anginosus group (including S. anginosus, S. intermedius, S. constellatus).
What other drugs will affect dalbavancin?
Other drugs may interact with dalbavancin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about dalbavancin
- Other brands: Dalvance
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about dalbavancin.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 1.01.
Date modified: November 30, 2016
Last reviewed: July 22, 2014