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User Reviews for Ceftriaxone

Ceftriaxone has an average rating of 8.6 out of 10 from a total of 141 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 8% reported a negative effect.

Condition Avg. Rating Reviews Compare
Urinary Tract Infection  
9.1
49 reviews 189 medications
Bacterial Infection  
8.6
38 reviews 171 medications
Pneumonia  
8.9
18 reviews 188 medications
Gonococcal Infection, Uncomplicated  
8.8
6 reviews 62 medications
Otitis Media  
8.8
6 reviews 137 medications
Lyme Disease, Neurologic  
5.7
4 reviews 34 medications
Joint Infection  
6.7
3 reviews 47 medications
Bronchitis  
6.3
3 reviews 288 medications
Kidney Infections  
7.0
3 reviews 94 medications
Lyme Disease  
9.5
2 reviews 36 medications
Typhoid Fever  
9.0
1 reviews 11 medications
Pelvic Inflammatory Disease  
3.0
1 reviews 66 medications
STD Prophylaxis  
10.0
1 reviews 26 medications
Skin or Soft Tissue Infection  
8.0
1 reviews 162 medications
Gastroenteritis  
9.0
1 reviews 22 medications
Gonococcal Infection, Disseminated  
10.0
1 reviews 16 medications
Skin and Structure Infection  
10.0
1 reviews 76 medications
Intraabdominal Infection  
10.0
1 reviews 58 medications
Bone infection  
6.0
1 reviews 65 medications
Summary of Ceftriaxone reviews 8.6 141 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Ceftriaxone

Anonymous January 9, 2012

Rocephin (ceftriaxone) for Urinary Tract Infection: “Received Rocephin injection in left hip for urinary tract infection. The injection itself was not any worse than any other I've received, but as the medicine starts making its way into the body it becomes very uncomfortable. It feels very bruised and knotty at the injection site. However, I know this medicine works very well for this condition as I've had this twice previously, otherwise I would not put myself through the discomfort. It is only painful from about 2-3 minutes following the injection up to about 30 minutes following when the pain wears down to barely noticeable except when the area is touched. Its highly worth the brief pain and discomfort. I always feel much better within 24 hours following the shot.”

9 / 10
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Chronicbv · Taken for less than 1 month July 29, 2019

Rocephin (ceftriaxone) for Bacterial Infection: “I had suffered from bacterial vaginosis for 3 + years. I constantly was treated with metronidazole (pills & gel) and it would immediately creep on back within days of finishing my medicine. Finally when I went to the ER with terrible pains in my abdomen I was told I had PID. They treated me with a shot of rocephin and I haven’t had BV in over a year. It’s a miracle. Doctors should be treating patients with this instead of flagyl/metronidazole. That doesn’t work! This shot kills it once and for all.”

10 / 10
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Mandy · Taken for less than 1 month April 29, 2020

Rocephin (ceftriaxone) for Bacterial Infection: “I had my first sinus infection this year. I suffered from continuous low grade fevers, headaches, sore throat, ears and sinuses aching and lymph nodes all swollen for weeks. Finally went to urgent care. I was given Augmentin for 10 days with absolutely no improvement. I went back and was given a shot of rocephin and tordal. Within 2 days, almost 100% back to normal. Also started 7 days of Levaquin. Unfortunately infection came back within 2 weeks. I got another shot Rocephin today and within hours have started feeling better. It only burns a little. I did not have any side effects either time. Completely worth it!!!”

9 / 10
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betternow January 10, 2010

Rocephin (ceftriaxone) for Urinary Tract Infection: “Was given this after ER visit with severe testicular, urethra, and kidney pain. Tests for STD's were negative (ER did this anyway), so only conclusion was very bad UTI. Medicine (shot in buttocks) cleared up problem within 72 hrs, even though azithromycin (1 g dose) given for bronchitis 1 week earlier did not.”

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Amy September 30, 2019

Rocephin (ceftriaxone) for Urinary Tract Infection: “Second time posting hoping it might help someone. Had symptoms of UTI on Friday. Not happy all weekend. Got into doctor this morning and had shot. I still hate getting two shots in my bottom but my doctor also insists on giving me a B12 shot when I see him because I am slightly anemic. I am not sure if it is because I am skinny but Rocephin burns like heck and I am almost in tears getting it. Maybe I am just a wimp but I don’t like needles getting stuck in me and Rocephin is the worst! It it is now around 3:00 and I have no symptoms. It works and even though I dreaded the shot all weekend I am glad I got it.”

9 / 10
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being a woman isn't fun · Taken for less than 1 month May 27, 2015

Rocephin (ceftriaxone) for Urinary Tract Infection: “I've gotten uti's twice a year for over a decade. Azo doesn't even take a little of the pain away...mine are always terrible! Uti hit me hard yesterday and I went to the clinic I asked for this shot based on people on the Internet saying it helped so fast. It's true. The shot hurts but nothing is worse than the pain of the uti. I felt better within hours. It's usually a couple of days before I get to feeling better using antibiotic pills so I definitely recommend the shot!!”

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BityBom April 14, 2016

Rocephin (ceftriaxone) for Urinary Tract Infection: “42 year old female. 1 month ago I got went to urgent care for UTI. I was given Cipro. The burning never went away. I finished all the antibiotics and say by Gyn. Had another urine test along with a Pap. All were normal. This entire week I felt bad. Extremely tired, shakey, weak, irritable and of course the burning that never stopped. Went to urgent care tonight. I saw a young male physicians assistant. He suggested a rocephin shot. It hurt like heck but 3 hours after the shot, it's like I'm healed instantly. My whole body feels 100%better. I think the burning is finally gone. I hope I feel this great tomorrow. It's been one miserable month.”

10 / 10
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Frequently asked questions

worrying wife · Taken for less than 1 month December 13, 2016

Rocephin (ceftriaxone) for Bacterial Infection: “my husband was given a shot of rocephine within seconds he was in anaphylactic shock. He was given benedryll to reverse the medication. He was rushed to the hospital his blood pressure shot thru the roof he nearly died. From the shot he suffers from serum sickness, high blood pressure, irreg heart beat, extreme sweating, restless leg sydrom,, headaches, loss of appetite, PTSD, extreme panick attacks, hyperactivity, insomnia, flushing, jitters all the time, fear, depression, chest pain, feeling of discomfort. Loss of dignity, my husband is a different person and this drug did this to him. It is a daily struggle every moments to keep positive and hope for a cure to fix his neurological damage this shot has caused”

1 / 10
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Preggo · Taken for less than 1 month October 19, 2014

Rocephin (ceftriaxone) for Urinary Tract Infection: “Thank God for this shot! Doc had me on cephalaxin which only made it worse and then macro if which made me deathly sick. I couldn't take it anymore since I was pregnant and already miserable! OB gave me this shot in right hip and I couldn't feel more better. Turns out I don't have any pregnancy symptoms it was the urinary tract infection making me feel so awful! I felt better an hour after the shot and have been actually able to eat more than 2 bites of food since! Worth the burn and soreness afterwords.”

10 / 10
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Brenda Bean · Taken for less than 1 month March 30, 2013

Rocephin (ceftriaxone) for Pneumonia: “Sick for 4 weeks, went to Doctor. Ear infection, sinus infection and bronchitis prescriptions of Augmentin and Mucinex. Since 6 months earlier I had pneumonia that took me out of work for short term disability, when I heard the tell tale "rattling" on my left side 8 days later, went back to Doctor. So after 5 weeks of coughing, sneezing, headaches and overwhelming tiredness, I received a shot of this. I had not had a shot of anything for many years and it did hurt. I am not a wimpy, owy person. It did hurt. It hurt for 45 minutes. But the next morning, I woke without coughing up a lung, rested, and feeling better than I had for a month. The second day (now) I am headed out to cut the grass after vacuuming the house. Yeah.”

9 / 10
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Dibursian · Taken for less than 1 month December 22, 2014

Rocephin (ceftriaxone) for Urinary Tract Infection: “10 weeks pregnant and found out I had a bladder infection/urinary tract infection. Doctor first prescribed Macro. Those were the worst 3 days ever. I could not stop throwing up. The smell of food made me nauseous. I was weak and did not move from the bed for 3 day which is not like me at all. I am a very active person. I called the on-call doctor on Sunday night and she told me to stop taking Macro and to come in tomorrow to get the Rocephin shot. I have to say just from one day of being off Macro I already feel better but not 100%. I took the Rocephin shot and started to feel better little by little after 3 hours. I expected for the shot to hurt a lot. However, it only burned a little for a short period of time.”

9 / 10
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kwaggs January 21, 2017

Rocephin (ceftriaxone) for Urinary Tract Infection: “Had a severe UTI that didn't respond to Macrobid or Ceftin. My doctor ordered a shot of Rocephin, this is a miracle drug! The horrible pain I've had for over a week was gone in a few hours. I would definitely recommend this and would take it again even though the injection was a little painful!”

10 / 10
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RelievedMama January 26, 2017

Rocephin (ceftriaxone) for Urinary Tract Infection: “My 11 yr old had 102 temp for 2 days, achy all over. Day 3 104. Went to clinic. Negative for flu and strep and white count normal. Advised to push fluids and treat fever. Day 4 temp 105. Went back to clinic. Urinary Analysis shows raging UTI and now she's really dehydrated. Had 2 options, shot of rocephin, push fluids and start oral antibiotics but if not better by morning she'd be admitted to hospital. Or just admit her right then. We went with the shot. Within an hour I saw vast improvements. Fever has not been above 100.5, pain is better, drinking better and even managed to eat a little bit and work on 4 days of homework! Would definitely recommend rocephin!”

10 / 10
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Anomymous · Taken for less than 1 month November 18, 2019

Rocephin (ceftriaxone) for Bacterial Infection: “I have sick for 3 weeks! 21 days of coughing green phlegm and having the worse symptoms I have ever experienced. I get sick frequently so I decided to try to let my immune system work on its own. I've been dragging myself around trying to deal with symptoms while still taking care of my kids. I gave in and went to urgent care this morning. I received a rocephin injection and oral antibiotics. Within HOURS, I felt better.”

10 / 10
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Shanna2012 January 5, 2012

Rocephin (ceftriaxone) for Pneumonia: “I've been sick with what I thought was just a cold for the last 3 weeks and finally my cough got so bad the other day that it hurt in my back every time I coughed or took a deep breath. I went to the urgent care clinic and found out I have walking pneumonia. They gave me a shot of Rocephin and Dexatron. It didn't even take 30 mins. for it to begin working on my breathing and my lungs. I was already feeling halfway better when I left the doctors office and when I woke up today I feel almost back to normal. With the exception of my right buttock a little tender from the shots and I have a little leg pain. I am so thankful for this shot.I have been in misery for the last 3 weeks and it took less than 24 hours for this medicine to start healing.”

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gjubl August 23, 2016

Rocephin (ceftriaxone) for Urinary Tract Infection: “Have been in agony with uti after uti burning and sick and debilitated and no other antibiotics touched it. Had positive strep b culture. Finally feel relief after Rocefin injection. It also helped before quickly with sinus infection. Highly recommend. Antibiotics are awful with deadly side effects. Ciprofloxacin and Levaquin can kill you. Research those two on side effects.”

10 / 10
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#1 October 18, 2013

Rocephin (ceftriaxone) for Pneumonia: “Had a 102 degrees temp for 4 days, 101 degrees for 4 days. Felt like I was coughing up my lungs and could not catch my breath. Sounded like a gurgling sound in my lungs all the time. Was the worst I ever felt. Went to Dr. and got a shot and within 6 hrs I was ready to go cut the grass.”

10 / 10
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gtags November 14, 2019

For Gonococcal Infection, Uncomplicated: “I was treated by this med ceftriaxone because of gonorrhea and I had worst side effects, I felt weak and tired after 2 days taking the antibiotic and it last weeks. Did anyone experience the same side effects.!?”

7 / 10
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Skky · Taken for less than 1 month August 3, 2020

Rocephin (ceftriaxone) for Urinary Tract Infection: “This is my 3rd UTI in an annual year. One in Oct of 2019, May 2020 and Aug 2020. I woke up at 2 am 2 days ago feeling that all so familiar feeling. By 1pm Sunday I headed to the ER. I started urinating blood, passing clots and my pelvic area was killing me! A UTI causes INTENSE pain, I would birth my 4 children all over again! Doc did a phone call appt (due to covid) today and he said I am perimenopausal(sp) at 38 years old :/. My estrogen is funky so that could def be a culprit. I did have the rocephin shot last night, but it's taking a bit longer to COMPLETELY go away vs the last 2x. I am TERRIFIED of getting another UTI. My doc suggested a natural supplement call de mannose. Anyone taking this? I have to order it, drug store was out. Apparently it's a preventative supplement for UTI's. All I know is that the pain of a UTI is forever traumatizing! The shot hurts, yes, but SO worth the relief. I would recommend it to anyone.”

10 / 10
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Apolk · Taken for less than 1 month December 30, 2016

Rocephin (ceftriaxone) for Urinary Tract Infection: “Because of chronic UTIs in my past, I had developed resistance to almost all antibiotics for treatment. Including Cipro, Bactrim, Amoxicillin and macrobid. Either they made me sick with flu like aches and pains or just did not cure infection. Rocephin shot was prescribed and done last time in doctor's office, felt better within hours. And have to say until tonight, it had been 8 months since my last UTI. That is definitely a record for me! Given the shot again today, hoping for same results...”

8 / 10
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Feeling better September 9, 2018

Rocephin (ceftriaxone) for Urinary Tract Infection: “I have been getting UTIs for many years. Usually take Bactrim or Cipro. Had such a bad one, plus pain in my back and I felt like the Bactrim was making me feel awful too. I ended up going to ER because I have only 1 kidney and can’t allow a kidney infection to set it. I got a Rocephin IV and it is now 9 hrs later and I feel so much better! It's still soon to say it completely cured it, but I am actually having real relief for the first time in 5 days. Why didn’t I ever hear about this drug before?”

10 / 10
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QuietBloom · Taken for less than 1 month August 19, 2016

Rocephin (ceftriaxone) for Bacterial Infection: “I've had a persistent UTI and been through 2 rounds of oral antibiotics and it kept coming back despite having had a culture done to determine what would be effective. Once the pain got bad enough that the pyridium was no longer effective, I called the doctor and begged for help while still waiting for the second culture results. They gave me a shot of Rocephin. By morning I felt 85% better. The second day, I still feel a twinge of symptom here and there, but feel soooo much better. The shot hurts, yes. But it's not THAT bad, and there is was lidocaine in my injection to help with that. Powerful stuff - so glad they gave it to me!”

10 / 10
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Uncle Fred · Taken for less than 1 month December 22, 2013

Rocephin (ceftriaxone) for Pneumonia: “I'm a healthy 71 year old male with one weakness - my lungs. I've had bronchitis as a boy and had pneumonia twice before and this is the third time getting pneumonia. The Rocephin was added to an slow intravenous drip. Good relief the first day and today, the second day of treatment, I got my appetite back. I have one more day of intravenous and I think I may be back to near normal.”

10 / 10
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TamaraBeth December 2, 2015

Rocephin (ceftriaxone) for Pneumonia: “I have been so sick I had average of 104 temp. Couldn't breathe. I went to the dr. They ran tests and xrays turns out I had pneumonia. They fave me two shots a steroid and also this besides my butt feeling sore I feel so much better. I also was given antibiotics. But three hours after this shot I can breathe without mini painful short breathes.”

10 / 10
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Lynne June 16, 2018

Rocephin (ceftriaxone) for Urinary Tract Infection: “Recurrent UTI and bladder infections, Last year need hospitalization, turning to sepsis. Three days of UV Rocephin and ten months later, another UTI and after a shot of rocephin, started clearing up the symptoms immediately! Oral antibiotics never work! This is a miracle drug for this condition, with no side effects for me!”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.