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Dalbavancin Dosage

Medically reviewed by Last updated on Sep 22, 2021.

Applies to the following strengths: 500 mg

Usual Adult Dose for Skin and Structure Infection

1000 mg IV, followed one week later by 500 mg IV

Comments: Infuse over 30 minutes.

Uses: Treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of the following Gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), Streptococcus pyogenes, Streptococcus agalactiae and Streptococcus anginosus group (including S. anginosus, S. intermedius, S. constellatus).

Renal Dose Adjustments

Mild to moderate renal impairment (CrCl 30 to 79 mL/min): No adjustment recommended
Severe renal impairment (CrCl less than 30 mL/min): 750 mg IV, followed one week later by 375 mg IV.

Liver Dose Adjustments

Mild hepatic impairment (Child-Pugh Class A): No adjustment recommended
Moderate to severe hepatic impairment (Child-Pugh Class B or C): Data not available; use with caution


Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.


Hemodialysis: No adjustment recommended. Dalbavancin can be administered without regard to the timing of hemodialysis.
Peritoneal dialysis: Data not available

Other Comments

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

IV compatibility:
-Do not co-infuse with other medications or electrolytes.
-Saline-based infusion solutions may cause precipitation and should not be used.
-If the IV line is used to administer other drugs, flush the line with 5% Dextrose injection before and after each dalbavancin infusion.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.