Medically reviewed by Drugs.com. Last updated on Oct 2, 2018.
Applies to the following strengths: 500 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Skin and Structure Infection
1000 mg IV, followed one week later by 500 mg IV
Comments: Infuse over 30 minutes.
Uses: Treatment of adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of the following Gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), Streptococcus pyogenes, Streptococcus agalactiae and Streptococcus anginosus group (including S. anginosus, S. intermedius, S. constellatus).
Renal Dose Adjustments
Mild to moderate renal impairment (CrCl 30 to 79 mL/min): No adjustment recommended
Severe renal impairment (CrCl less than 30 mL/min): 750 mg IV, followed one week later by 375 mg IV.
Liver Dose Adjustments
Mild hepatic impairment (Child-Pugh Class A): No adjustment recommended
Moderate to severe hepatic impairment (Child-Pugh Class B or C): Data not available; use with caution
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Hemodialysis: No adjustment recommended. Dalbavancin can be administered without regard to the timing of hemodialysis.
Peritoneal dialysis: Data not available
Reconstitution/preparation techniques: The manufacturer product information should be consulted.
-Do not co-infuse with other medications or electrolytes.
-Saline-based infusion solutions may cause precipitation and should not be used.
-If the IV line is used to administer other drugs, flush the line with 5% Dextrose injection before and after each dalbavancin infusion.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about dalbavancin
Other brands: Dalvance