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Carbapenems

What are Carbapenems

Carbapenems are a class of beta-lactam antibiotic that are active against many aerobic and anaerobic gram-positive and gram-negative organisms. Thienamycin was the first carbapenem to be discovered in 1976. Carbapenems are notable for their ability to inhibit beta-lactamase enzymes (also called penicillinase) - a type of enzyme that greatly reduces the activity of antibiotics such as penicillins and cephamycins. Of all the beta-lactam antibiotics, carbapenems possess the broadest spectrum of activity and the greatest potency against bacteria. Because of this, they are often reserved for more severe infections or used as "last-line" agents.

Carbapenems inhibit bacterial cell wall synthesis by binding to the penicillin-binding proteins and interfering with cell wall formation.

List of Carbapenems:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
Doribax (Pro, More...)
generic name: doripenem
1 review
   
10
Merrem (Pro, More...)
generic name: meropenem
0 reviews
   
6.0
Invanz (Pro, More...)
generic name: ertapenem
0 reviewsAdd rating
Primaxin IM (Pro, More...)
generic name: cilastatin/imipenem
0 reviewsAdd rating
Primaxin IV (Pro, More...)
generic name: cilastatin/imipenem
0 reviewsAdd rating
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