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Zyvox (linezolid) Drug Interactions

A total of 1009 drugs are known to interact with Zyvox (linezolid).

  • 434 major drug interactions
  • 572 moderate drug interactions
  • 3 minor drug interactions

Show all medications in the database that may interact with Zyvox (linezolid).

Check for interactions

Type in a drug name to check for interactions with Zyvox (linezolid).

Most frequently checked interactions

View interaction reports for Zyvox (linezolid) and the medicines listed below.

  • Adderall (amphetamine / dextroamphetamine)
  • albuterol (Ventolin HFA, Ventolin, ProAir HFA, Proventil, Proventil HFA, ProAir RespiClick, AccuNeb, Respirol, Volmax, Vospire ER, ProAir Digihaler, Airet)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Bufferin, Fasprin, Arthritis Pain, Easprin, Aspergum, Aspiritab, Halfprin, Empirin, Ascriptin Enteric, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Entercote, St. Joseph Aspirin, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Benadryl (diphenhydramine)
  • Cipro (ciprofloxacin)
  • clindamycin (Cleocin, Cleocin Phosphate, Cleocin Pediatric, Cleocin HCl, Cleocin Phosphate ADD-Vantage)
  • Coumadin (warfarin)
  • Cymbalta (duloxetine)
  • Dextrose (glucose)
  • fentanyl (Fentanyl Transdermal System, Duragesic, Actiq, Sublimaze, Fentora, Subsys, Abstral, Lazanda, Onsolis, Ionsys)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • Lasix (furosemide)
  • Levaquin (levofloxacin)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • meropenem (Merrem, Merrem Novaplus)
  • metoprolol (Metoprolol Succinate ER, Metoprolol Tartrate, Lopressor, Toprol-XL, Kapspargo Sprinkle)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Oxyfast, Oxecta, RoxyBond, Percolone, Dazidox, Oxydose, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • Protonix (pantoprazole)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, ConZip, Ultram ER, Zydol, Tramahexal, Zamadol, Ryzolt, Tramal SR, Larapam SR, GenRx Tramadol, Tramahexal SR, Tramedo, Zydol XL, Rybix ODT, Ultram ODT)
  • Tylenol (acetaminophen)
  • vancomycin (Vancocin, Firvanq, Vancocin HCl, Lyphocin, Vancocin HCl Pulvules)
  • Vitamin D3 (cholecalciferol)
  • Zofran (ondansetron)
  • Zoloft (sertraline)
  • Zosyn (piperacillin / tazobactam)

Zyvox (linezolid) alcohol/food interactions

There are 2 alcohol/food interactions with Zyvox (linezolid)

Zyvox (linezolid) disease interactions

There are 12 disease interactions with Zyvox (linezolid) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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