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Spironolactone Drug Interactions

Currently displaying a list of 656 drugs known to interact with spironolactone.

See also: The most common drugs checked in combination with this medicine.

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Type in a drug name to check for interactions with spironolactone.

Medications known to interact with spironolactone

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    • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Children's Motrin, Proprinal, Motrin IB, Childrens Ibuprofen Berry, Advil Children's, Ibuprofen PMR, Ibu-8, Rufen, IBU-200, Motrin Childrens, Advil Migraine, Caldolor, Ibu-Tab, Menadol, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Pediatric, Genpril, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, NeoProfen, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
    • ibuprofen / oxycodone (Combunox)
    • ibuprofen / phenylephrine (Advil Congestion Relief, Advil Sinus Congestion & Pain)
    • ibuprofen / pseudoephedrine (Advil Cold and Sinus, Advil Cold and Sinus Liqui-Gels, Dristan Sinus, Motrin IB Sinus, Sine-Aid IB, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Advil Children's Cold)
    • idarubicin (Idamycin PFS, Idamycin)
    • iloperidone (Fanapt)
    • iloprost (Ventavis)
    • imipramine (Tofranil, Tofranil-PM)
    • indomethacin (Indocin, Indocin SR, Tivorbex, Indocin IV)
    • iodamide (Renovue-Dip, Renovue-65)
    • iodipamide (Cholografin Meglumine)
    • iodixanol (Visipaque)
    • iohexol (Omnipaque 300, Omnipaque 12, Omnipaque 240, Omnipaque 180 Redi-Unit, Omnipaque 9, Omnipaque 350, Myelo-Kit, Omnipaque 140, Omnipaque 180, Omnipaque 210, Omnipaque 240 Redi-Unit, Omnipaque Flexipak, Oraltag)
    • iopamidol (Isovue-200, Isovue-370, Iopamidol-370, Isovue-128, Isovue-M-200, Isovue-250, Isovue-300, Isovue-M-300)
    • iopromide (Ultravist)
    • iothalamate (Conray, Cysto-Conray II, Cysto-Conray, Conray-30, Conray-43, Conray-400)
    • ioversol (Optiray 320, Optiray 240, Optiray 160, Optiray 350, Optiray 300)
    • ioxaglate (Hexabrix)
    • ioxilan (Oxilan)
    • irbesartan (Avapro)
    • irinotecan (Camptosar)
    • irinotecan liposomal (Onivyde)
    • isocarboxazid (Marplan)
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    Spironolactone alcohol/food interactions

    There is 1 alcohol/food interaction with spironolactone

    Spironolactone disease interactions

    There are 7 disease interactions with spironolactone which include:

    Drug Interaction Classification

    These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No interaction information available.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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