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Retin-A (tretinoin topical) Drug Interactions

A total of 34 drugs are known to interact with Retin-A (tretinoin topical).

  • 34 moderate drug interactions

Show all medications in the database that may interact with Retin-A (tretinoin topical).

Check for interactions

Type in a drug name to check for interactions with Retin-A (tretinoin topical).

Most frequently checked interactions

View interaction reports for Retin-A (tretinoin topical) and the medicines listed below.

  • Accutane (isotretinoin)
  • albuterol (Ventolin, Ventolin HFA, ProAir HFA, Proventil, Proventil HFA, ProAir RespiClick, AccuNeb, Respirol, Vospire ER, Volmax, ProAir Digihaler, Airet)
  • aspirin (Aspir 81, Ecotrin, Aspirin Low Strength, Acetylsalicylic Acid, Bayer Aspirin, Aspir-Low, Bufferin, Ascriptin, Arthritis Pain, Aspiritab, Aspergum, Fasprin, Halfprin, Easprin, Ecotrin Adult Low Strength, Empirin, Migralex, Aspi-Cor, St. Joseph 81 mg Chewable Aspirin, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Ecotrin Maximum Strength, Entercote, Bufferin Extra Strength, Ascriptin Enteric, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspirtab, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, St. Joseph Aspirin, Stanback Analgesic, Norwich Aspirin, Acuprin 81, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Aspirin Lite Coat, Heartline, Bayer Advanced Aspirin, Buffasal)
  • clindamycin topical (Cleocin T, Clindagel, Clindesse, Cleocin Vaginal, Clindamax, Cleocin Ovules, ClindaReach Pledget, Clindacin P, Evoclin, Clindets, C/T/S, Clinda-Derm, Clindets Pledget, Pledgaclin, Clindacin ETZ, Clindacin PAC)
  • cyclobenzaprine (Flexeril, Amrix, Fexmid, Comfort Pac with Cyclobenzaprine)
  • doxycycline (Vibramycin, Oracea, Monodox, Doxy 100, Doryx, Adoxa, Targadox, Morgidox, Acticlate, Vibra-Tabs, Doxy-Caps, Periostat, Doxy 200, Oraxyl, Doryx MPC, Doxy-D, Alodox, Adoxa Pak, Avidoxy, Adoxa TT, Adoxa CK, Ocudox, LymePak, Uracil, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • Flonase (fluticasone nasal)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • Klonopin (clonazepam)
  • melatonin (Melatonin Time Release, SGard, Bio-Melatonin, Health Aid Melatonin, VesPro Melatonin)
  • meloxicam (Mobic, Vivlodex, Qmiiz ODT)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Sterapred DS, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • spironolactone (Aldactone, CaroSpir)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)
  • Zyrtec (cetirizine)

Retin-A (tretinoin topical) disease interactions

There are 2 disease interactions with Retin-A (tretinoin topical) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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