Solodyn Dosage

Generic name: minocycline hydrochloride 45mg
Dosage form: tablet, film coated, extended release

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The recommended dosage of SOLODYN is approximately 1 mg/kg once daily for 12 weeks. Higher doses have not shown to be of additional benefit in the treatment of inflammatory lesions of acne, and may be associated with more acute vestibular side effects.

The following table shows tablet strength and body weight to achieve approximately 1 mg/kg.

Table 1: Dosing Table for SOLODYN
Patient's Weight (lbs)	Patient's Weight (kg)	Tablet Strength (mg)	Actual Dose mg/kg
* No longer distributed or sold by Valeant.
99 – 109	45 – 49	45*	1 – 0.92
110 – 131	50 – 59	55	1.10 – 0.93
132 – 157	60 – 71	65	1.08 – 0.92
158 – 186	72 – 84	80	1.11 – 0.95
187 – 212	85 – 96	90*	1.06 – 0.94
213 – 243	97 – 110	105	1.08 – 0.95
244 – 276	111 – 125	115	1.04 – 0.92
277 – 300	126 – 136	135*	1.07 – 0.99

SOLODYN Tablets may be taken with or without food [see Clinical Pharmacology (12.3)]. Ingestion of food along with SOLODYN may help reduce the risk of esophageal irritation and ulceration.

In patients with renal impairment, the total dosage should be decreased by either reducing the recommended individual doses and/or by extending the time intervals between doses [see Warnings and Precautions (5.4)].