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Medications for Prostatitis

Other names: Chronic Pelvic Pain Syndrome; Chronic Prostate Pain; Chronic Prostatitis; CP; CPPS

Prostatitis is a swelling and inflammation of the prostate gland. The prostate gland is a small walnut-shaped gland that sits just below the bladder and surrounds the urethra in men. It secretes prostate fluid, one of the main components of semen.

Prostatitis can develop in men of all ages, but more commonly affects men between the ages of 30 and 50. There are 2 main types:

  • chronic prostatitis:  most common, not usually infection-related, symptoms come and go over several months
  • acute prostatitis: rare, symptoms come on suddenly and require immediate treatment, usually caused by an infection

What are the Symptoms of Prostatitis?

Symptoms differ depending on whether the prostatitis is acute or chronic.

Symptoms of acute prostatitis may include:

  • Pain around the penis, testicles, anus, lower abdomen or lower back. May be severe
  • Pain when defecating (passing poo)
  • Pain when urinating (peeing), frequent urination (especially at night, urgent urination, problems starting or "stop-start" peeing, or blood in the urine
  • Complete inability to urinate (this is a medical emergency)
  • Feeling unwell, with aches, pains and possibly a fever
  • Thick discharge from the penis

Symptoms of chronic prostatitis generally last for at least 3 months and may include:

  • Pain around the penis, testicles, anus, lower abdomen or lower back. May be severe
  • Pain when urinating (peeing), frequent urination (especially at night, urgent urination, problems starting or "stop-start" peeing, or blood in the urine
  • An enlarged or tender prostate on rectal examination, although in some cases it may be normal
  • Erectile dysfunction, pain when ejaculating or pelvic pain after sex.

How is Prostatitis Treated?

See your doctor straight away if develop sudden and severe symptoms of prostatitis. Acute prostatitis is usually treated with painkillers and a two to four-week course of antibiotics. Hospital treatment may be necessary if you are unable to pass urine.
If you have symptoms of chronic prostatitis, you may be referred to a urologist who specializes in genitourinary problems and management.  Treatment may include:

  • Painkillers
  • Alpha-blockers – these help relax the muscles in the prostate gland and at the base of the bladder
  • Antibiotics.

Drugs used to treat Prostatitis

The medications listed below are related to or used in the treatment of this condition.

Filter
Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
ciprofloxacin 4.0 84 reviews for ciprofloxacin to treat Prostatitis
Rx C N
Generic name:
ciprofloxacin systemic
Brand names:
Cipro, Cipro XR, Cipro I.V.
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Cipro 5.4 22 reviews for Cipro to treat Prostatitis
Rx C N
Generic name:
ciprofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
doxycycline 5.6 17 reviews for doxycycline to treat Prostatitis
Rx D N X
Generic name:
doxycycline systemic
Brand names:
Doxy 100, Vibramycin, Doryx, Monodox, Oraxyl, Doryx MPC
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
oxybutynin Off-label 8.0 1 review for oxybutynin to treat Prostatitis
Rx/OTC B N X
Generic name:
oxybutynin systemic
Drug class:
urinary antispasmodics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
sulfamethoxazole / trimethoprim 4.5 52 reviews for sulfamethoxazole / trimethoprim to treat Prostatitis
Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Brand names:
Bactrim, Co-trimoxazole, Septra DS, Septra, Sulfatrim Pediatric
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
levofloxacin 4.7 24 reviews for levofloxacin to treat Prostatitis
Rx C N
Generic name:
levofloxacin systemic
Brand name:
Levaquin
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cephalexin 10 2 reviews for cephalexin to treat Prostatitis
Rx B N
Generic name:
cephalexin systemic
Brand name:
Keflex
Drug class:
first generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Levaquin 4.6 13 reviews for Levaquin to treat Prostatitis
Rx C N
Generic name:
levofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Bactrim 2.8 16 reviews for Bactrim to treat Prostatitis
Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Doxy 100 10 1 review for Doxy 100 to treat Prostatitis
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Keflex Rate Add review
Rx B N
Generic name:
cephalexin systemic
Drug class:
first generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
moxifloxacin Off-label 6.2 7 reviews for moxifloxacin to treat Prostatitis
Rx C N
Generic name:
moxifloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Vibramycin Rate Add review
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Doryx Rate Add review
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Monodox Rate Add review
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ofloxacin 5.5 4 reviews for ofloxacin to treat Prostatitis
Rx C N
Generic name:
ofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Oraxyl Rate Add review
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
ceftriaxone Rate Add review
Rx B N
Generic name:
ceftriaxone systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Cipro XR 0.0 1 review for Cipro XR to treat Prostatitis
Rx C N
Generic name:
ciprofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Co-trimoxazole Rate Add review
Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Doryx MPC Rate Add review
Rx D N X
Generic name:
doxycycline systemic
For consumers:
dosage, interactions, side effects
Septra DS 1.0 1 review for Septra DS to treat Prostatitis
Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
Cipro I.V. Rate Add review
Rx C N
Generic name:
ciprofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
Septra 1.0 1 review for Septra to treat Prostatitis
Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sulfatrim Pediatric Rate Add review
Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects

Frequently asked questions

Learn more about Prostatitis

Care guides

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.