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Sulfamethoxazole / trimethoprim User Reviews & Ratings (Page 2)

Brand names: Bactrim, Bactrim DS, SMZ-TMP DS, Septra, Co-trimoxazole, Septra DS, Bactrim Pediatric, Bactrim IV Sulfatrim Pediatric Bethaprim Bethaprim Pediatric …show all brand names

Sulfamethoxazole / trimethoprim has an average rating of 4.9 out of 10 from a total of 1,720 reviews on Drugs.com. 34% of reviewers reported a positive experience, while 47% reported a negative experience.

Reviews for Sulfamethoxazole / trimethoprim

Commonly mentioned side effects
  • Kd0...
  • Taken for less than 1 month
  • June 27, 2020

Sulfamethoxazole / trimethoprim for Bacterial Infection "I took Bactrim for 4 days. On the 4th day, I started having leg pain. The day after I quit the meds, I had all-over body aches, a low-grade temp off and on, and just a feeling of being sick. The next day, my aches went away but held on to the low-grade temp, headache, and weakness for two more days. During the course of the medication, I also had a pounding heart and no appetite. It did clear the infection though. I think I had a bad reaction and only wanted to report these so that others might know if they have the same thing happening to them. It took about 5 days from my last pill that I feel better."

2 / 10
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  • ira...
  • June 3, 2016

Sulfamethoxazole / trimethoprim for Bacterial Skin Infection "Day 3 on BACTRIM due to MRSA. Abscess was lanced and drained 5 days ago. Swelling/pain of the abscess has finally begun remission. I did suffer from the reported migraine headache all day yesterday, and it was quite debilitating, but no such headache today, and I'm finally back at work. Also suffered from some seriously painful abdominal cramps that produced very loose/watery stool. Not much of an appetite today and feeling a little shaky, so make sure you eat even if you don't want to. This drug is definitely very effective for the treatment of MRSA. If the migraines were constant as others described, I wouldn't not be back at work today. All my best wishes to everyone reading this."

10 / 10
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117 Report
  • Amy...
  • August 23, 2014

Sulfamethoxazole / trimethoprim for Acne "I love this. It is the ONLY thing that has ever cleared up my acne (face and body) completely. I've tried Proactiv, Retin-A, salicylic acid products, benzoyl peroxide products, the sun, avoiding the sun, only skin-healthy foods, enough sleep, etc., etc. and nothing works long term consistently. Life is just miserable when you have to show a pimply face - you are perceived as ugly and not clean. I'll take the risks of too much antibiotic use over being treated poorly for my appearance."

10 / 10
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Frequently asked questions

  • Anonymous
  • August 5, 2011

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "I'm very obsessive. Somewhere around a few years ago, I started obsessing and being paranoid about medications. So, as I'm sure you are all doing right now, you're looking up reviews on this medication to determine if you'll take it. Just like I did. I almost gave myself a panic attack thinking about possibly taking this medicine and then having a serious allergic reaction. Luckily though, while speaking with my pharmacist, he let me know I took this medicine last year and I remembered I was fine. The point is, every medicine has adverse effects. Chances are, you won't have major side effects."

10 / 10
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  • Jae...
  • Taken for less than 1 month
  • December 23, 2020

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "Honestly, not terrible. I was prescribed Bactrim, 2 doses/day for 7 days after they prescribed Keflex (which didn’t work). A little nausea after the first couple of doses, some indigestion, some lower back pain. As long as you drink lots of water with the pill and throughout the day, the side effects are pretty mild. I had ginger chews and Pepto for stomach issues that worked well. Eat a big meal before you take the pill too. Kombucha, yogurt, and probiotics during and after the course will help your stomach heal. I would much prefer this over a kidney infection. If you’re having major side effects from day one, perhaps try something different. Everyone reacts differently!"

7 / 10
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  • Cel...
  • Taken for less than 1 month
  • November 2, 2019

Sulfamethoxazole / trimethoprim for Bacterial Infection "3 days into the course, and I am experiencing: 1. Very bad dizzy spells. 2. Feelings of great weakness. 3. Feelings of great anxiety. 4. Feelings like I am dying. 5. My head & stomach are aching up a storm. 6. I am nauseated & vomiting. 7. Vagina burning, that started on the second day. I HAVE had Bactrim before for UTIs but have NEVER experienced what I am with this darn one. My question is what have they put/added into the drug to make me react in such a horrid nasty way?"

4 / 10
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  • Lau...
  • January 8, 2020

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "I was prescribed Bactrim for a UTI. I felt fine the first day. By day 2, I experienced horrible symptoms or side effects. I was having severe anxiety, nausea, increased heart rate, and shaking in my body. I called my doctor, and she said to continue taking it, but after reading all of these reviews, I've decided to stop taking the antibiotics. It's so scary to see so many other women going through the same thing!"

1 / 10
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  • LaC...
  • October 7, 2014

Sulfamethoxazole / trimethoprim for Bacterial Skin Infection "I took Bactrim for a while now for bacteria of the hair follicles, and it has helped a lot, plus using dial soap. But every time I get boils, it heals them. I don't have any side effects to the medicine. Every time I get this infection, I have to take Bactrim because I can't take penicillin."

10 / 10
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  • lol...
  • Taken for less than 1 month
  • August 9, 2013

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "Bactrim did a great job! My whole lower part of the body hurt and burned, it was awful. I couldn't even walk for a while without feeling strong pain. Going to the toilet was a nightmare, and it happened every five minutes. I took Bactrim, and the symptoms got worse, but then in two days, I was cured. No pain, no nothing. Bactrim is perfect."

10 / 10
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  • Mat...
  • Taken for less than 1 month
  • April 25, 2020

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "I feel like it saved my life. I got my first UTI, and it was the most painful thing I've ever experienced. I didn't sleep for two days and was not only peeing blood but peeing clots of blood. My back ached, my hips ached, and I was completely exhausted. The morning after I took my first pill, all symptoms were gone. ALL SYMPTOMS WERE GONE. I, of course, was still exhausted, but that was from little sleep the previous days. I had zero side effects. Now I'm back to normal, loving life."

10 / 10
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  • Pat...
  • Taken for less than 1 month
  • May 6, 2016

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "I am the type of person who is sensitive to chemicals, smells, sounds, etc. I rarely need meds and recently had to take Bactrim DS for five days due to a UTI. I was sooo nervous about taking it. I was convinced I would be allergic to it, or at least have side effects. Well, all that worrying was for nothing. I took it as prescribed for five days with no problem at all! I hope you do well on it too if you need it!"

10 / 10
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  • The...
  • April 12, 2020

Sulfamethoxazole / trimethoprim for Bacterial Infection "Took Bactrim for 10 days... felt okay... a week after completing the Bactrim, I felt like I had the flu. Major insomnia and feeling the sweats and increased heart rate. Would never take it again... hoping to feel normal again!... drinking a ton of water... but will never take it again..."

9 / 10
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  • sti...
  • Taken for less than 1 month
  • October 17, 2019

For Bacterial Infection "Worst antibiotic ever. Felt like I was losing my mind for the 5 out of 10 prescribed days I took it. I thought about death constantly, and had severe anxiety/panic attacks. I felt high, like I was out of body. Weird, awful dreams. I am usually able to calm myself and just zen out, but not on this stuff. I literally asked God to take care of my son and husband when I die due to death-obsessed thoughts. Please ask for a different medicine if you can. Scary stuff."

1 / 10
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  • Aim...
  • Taken for less than 1 month
  • July 5, 2021

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "After reading about possible side effects and reading all of the negative reviews for Bactrim, I was scared to take it after the Macrobid failed to cure my UTI. After 7 days of taking Augmentin, which also failed to work and gave me diarrhea, I braced myself and took the Bactrim. I want to report that I had no side effects at all, and it cleared up my infection. I would advise anyone prescribed this drug for a UTI to go ahead and take it, and don’t drive yourself crazy with worry like I did."

10 / 10
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  • Anonymous
  • May 11, 2010

Sulfamethoxazole / trimethoprim for Diverticulitis "I have frequent episodes of diverticulitis. My doctor prescribed a 10-day supply of Bactrim DS. Many times, 10 days is not enough to completely clear up the problem, so I end up needing an additional 10 days' worth of medicine. I have not had any bad side effects from this drug. I wish someone would create a drug to prevent diverticulitis."

8 / 10
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  • Apr...
  • January 31, 2021

Sulfamethoxazole / trimethoprim for Bacterial Skin Infection "I went to dermatologists for five years because of cysts/boils that were on my butt. I'd get one, it would go away, and I'd get another one. Doctors would put me on expensive medication that did nothing. Then I found the best dermatologist in the city and waited for four months to see him. The doctor said I would take Bactrim/sulfa 500 mg 2x a day for 30 days. I did that, and they disappeared. He said some people have to take them for life, others would take them for 10 days when you have any little sign or a boil or cyst. I started taking the medication, and the cyst or boil disappears. What a miracle treatment it's been to me as a person prone to cysts and boils!!!"

10 / 10
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  • Anonymous
  • September 29, 2012

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "I asked my doctor for a different type of antibiotic to take for this urinary tract infection instead of Cipro. This is my second day taking Bactrim for my UTI, and I can already see improvement! It feels like the infection is almost gone. I do, however, get a little bit of an upset stomach, so eat something substantial just before taking it and drink a few more bottles of water than normal, and you will be golden!"

10 / 10
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101 Report
  • Liz...
  • Taken for less than 1 month
  • March 22, 2016

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "Take a breath. If you're speeding through all of these experiences, you're probably looking for potential side effects and reactions of other people. I know because I'm just like you. I can tell you the first day I took Bactrim, I had a horrible migraine. The worst I've had in months. But guess what? I also didn't drink coffee that day after having a constant intake for weeks. I had other problems like chills, but wait, I got this medicine for an infection! So many symptoms people experience are likely a result of other things. My UTI went away. I drank lots of water and milk with it. Other than experiencing a few more headaches and a bit of tiredness, I was fine."

8 / 10
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  • Acl...
  • Taken for less than 1 month
  • July 17, 2016

Sulfamethoxazole / trimethoprim for Bacterial Skin Infection "Currently on day 3 of a 10-day antibiotic blast of Bactrim after 2 days on Keflex. What I had originally thought was a pimple on my septum just inside my right nostril turned out to be a staph infection. I had lanced the 'pimple' when it came to a head, thinking it would provide relief, however, the infection spread across my nares and over the tip of my nose overnight. Went to urgent care as I instantly suspected staph as the culprit and was prescribed Keflex and Bactroban topical until my follow-up with my PCP. Infection showed moderate improvement at my follow-up, but was then prescribed Bactrim. Within 24 hours, the itch and swelling had completely subsided. By 48 hours, the sores were cluster-scabbing, and today they're falling off!"

10 / 10
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  • Vga...
  • Taken for less than 1 month
  • December 18, 2019

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "Had not read side effects, so did not realize what I felt was caused by the med. My first day on Bactrim, I had side effects of feeling achy and depressed. By day 3, I was shaking, shivering, anxious, and insomnia. By day 5, nausea, dizziness, 100 heart rate, very low blood pressure, extreme anxiety. Pain everywhere, pain in my kidneys, very dehydrated, painful muscle spasms. Day 6, was going to go to the emergency room when I realized it could be the Bactrim and read side effects. Find it difficult to believe a doctor would give this to anyone. It was horrible."

1 / 10
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  • Kas...
  • September 7, 2014

Sulfamethoxazole / trimethoprim for Acne "I'm 27 and struggle with hormonal cystic acne. I have been on this medication for about 3 months now. Prior to Bactrim, I was taking minocycline. Minocycline worked great but I developed a resistance to it in July 2013. From July 2013, I tried doxycycline, then erythromycin. I struggled trying to find a solution with my Kaiser dermatologist until I went to another dermatologist in June 2014. In June 2014, I tried Bactrim and it started clearing up my skin 3 days after using it. I was prescribed to take 1 pill twice daily. I take 1 in the morning and 1 at night. This medicine has saved me from depression, feeling dirty, and ugly. I hope I don't develop a resistance to it. My skin is completely clear."

9 / 10
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  • Tex...
  • January 20, 2013

Sulfamethoxazole / trimethoprim for Bacterial Skin Infection "If you are prescribed Bactrim, take a probiotic with each pill and the side effects usually go away. Probiotics are over the counter. Before I could not take Bactrim or Keflex. Now, no problem. I am on Bactrim for boils and taking the probiotic."

10 / 10
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  • myb...
  • February 28, 2014

Sulfamethoxazole / trimethoprim for Acne "I am 41 years old and have struggled all my life with acne. Having done Roaccutane, Minocycline and every other medication and topical ointment. At 41, I was over acne. This is a miracle medicine. Skin cleared up in about 7 days and is absolutely flawless. Can't speak highly enough of this medicine. I am acne-free for the first time in my life. Ask your doctor about this."

10 / 10
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  • Len...
  • September 2, 2021

For Bacterial Infection "This antibiotic is very effective at clearing most bacterial infections quickly. You'll usually feel improvements within 48 hours. But, as a bunch of other reviews have stated, Bactrim gave me terrible anxiety and had my heart pounding out of my chest for 10 hours straight. Sleeping is nearly impossible. So, 10/10 efficacy but 1/10 for side effects. I wouldn't take it again unless my life depended on it."

5 / 10
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  • Dan...
  • Taken for less than 1 month
  • June 11, 2014

Sulfamethoxazole / trimethoprim for Urinary Tract Infection "I used to get recurrent urinary tract infections but hadn't had one in 7 years. Just got one and they tried nitrofurantoin but it did nothing. I got Bactrim and the urgency and burning was gone within hours. I don't like taking antibiotics but UTIs are no joke. Bactrim worked for me and thank goodness. I get a little stomach ache but it beats the UTI symptoms!"

10 / 10
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