Omvoh Side Effects

Generic name: mirikizumab

Medically reviewed by Drugs.com. Last updated on Feb 6, 2025.

Note: This document provides detailed information about Omvoh.

Applies to mirikizumab: solution Side Effects associated with mirikizumab. Some dosage forms listed on this page may not apply specifically to the brand name Omvoh.

Applies to mirikizumab: solution.

Precautions

It is very important that the doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

This medicine may cause serious allergic reactions including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

Your body's ability to fight infection may be reduced while you are being treated with mirikizumab-mkr. It is very important that you call your doctor at the first signs of any infection. Check with your doctor right away if you have any of the following symptoms while using this medicine: fever, chills, cough or hoarseness, flu-like symptoms, lower back or side pain, painful or difficult urination, or unusual tiredness or weakness.

You will need to have a skin test for tuberculosis before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis test or been exposed to tuberculosis.

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.

While you are being treated with mirikizumab-mkrz and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Mirikizumab-mkrz may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get close to them and do not stay in the same room with them for very long. If you have questions about this, talk to your doctor.

Serious side effects of Omvoh

Along with its needed effects, mirikizumab (the active ingredient contained in Omvoh) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mirikizumab:

Other side effects of Omvoh

Some side effects of mirikizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to mirikizumab: intravenous solution, subcutaneous solution.

General adverse events

The most common adverse reactions reported are upper respiratory tract infection, headache, rash, and injection site reactions.^[Ref]

Cardiovascular

• Common (1% to 10%): Hypertension^[Ref]

Dermatologic

• Common (1% to 10%): Rash^[Ref]

Rash included macular rash, maculopapular rash, pruritic rash, and popular rash.^[Ref]

Gastrointestinal

• Common (1% to 10%): Ulcerative colitis, abdominal pain, diarrhea, gastroesophageal reflux disease
• Frequency not reported: Intestinal sepsis^[Ref]

Hematologic

• Common (1% to 10%): Anemia^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Increased AST, increased ALT^[Ref]

Immunologic

• Very common (10% or more): Anti-drug antibodies (up to 23%)^[Ref]

Local

• Common (1% to 10%): Injection site reactions^[Ref]

Injection site reactions included erythema, hypersensitivity, pain, reaction, and urticaria at the injection site.^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia^[Ref]

Nervous system

• Common (1% to 10%): Headache^[Ref]

Other

• Common (1% to 10%): Herpes viral infection, pyrexia, increased blood creatine phosphokinase, fatigue
• Frequency not reported: Listeria sepsis^[Ref]

Herpes viral infection included herpes zoster, herpes simplex, and oral herpes.^[Ref]

Respiratory

• Very common (10% or more): Upper respiratory tract infections (up to 14%)
• Frequency not reported: Pneumonia^[Ref]

Upper respiratory tract infections included COVID-19, nasopharyngitis, pharyngitis, rhinitis, oropharyngeal discomfort, oropharyngeal pain, tonsillitis, viral upper respiratory tract infection, acute sinusitis, and sinusitis.^[Ref]

See also:

Further information

Omvoh side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer