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Medications for Crohn's Disease

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Humira 4.8 62 reviews for Humira to treat Crohn's Disease Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Stelara 6.5 67 reviews for Stelara to treat Crohn's Disease Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
budesonide 6.6 19 reviews for budesonide to treat Crohn's Disease Rx C N
Generic name:
budesonide systemic
Brand name:
Entocort EC
Drug class:
inhaled corticosteroids, glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Entyvio 6.3 63 reviews for Entyvio to treat Crohn's Disease Rx B N
Generic name:
vedolizumab systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Remicade 5.2 21 reviews for Remicade to treat Crohn's Disease Rx B N
Generic name:
infliximab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mesalamine Off-label 6.7 33 reviews for mesalamine to treat Crohn's Disease Rx B N
Generic name:
mesalamine systemic
Drug class:
5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
azathioprine 5.0 15 reviews for azathioprine to treat Crohn's Disease Rx D N
Generic name:
azathioprine systemic
Brand names:
Imuran, Azasan
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Skyrizi 7.7 10 reviews for Skyrizi to treat Crohn's Disease Rx N
Generic name:
risankizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
adalimumab 4.8 64 reviews for adalimumab to treat Crohn's Disease Rx B N
Generic name:
adalimumab systemic
Brand names:
Humira, Amjevita, Cyltezo, Hadlima, Hyrimoz, Abrilada, Hulio, Idacio, Yuflyma, Yusimry, Simlandi
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Rinvoq 8.2 14 reviews for Rinvoq to treat Crohn's Disease Rx N
Generic name:
upadacitinib systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
sulfasalazine Off-label 8.3 15 reviews for sulfasalazine to treat Crohn's Disease Rx B N
Generic name:
sulfasalazine systemic
Drug class:
antirheumatics, 5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
vedolizumab 6.2 75 reviews for vedolizumab to treat Crohn's Disease Rx B N
Generic name:
vedolizumab systemic
Brand name:
Entyvio
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ustekinumab 6.5 74 reviews for ustekinumab to treat Crohn's Disease Rx B N
Generic name:
ustekinumab systemic
Brand names:
Stelara, Wezlana, Imuldosa, Otulfi, Pyzchiva, Selarsdi, Steqeyma, Yesintek
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
hyoscyamine Off-label 9.3 4 reviews for hyoscyamine to treat Crohn's Disease Rx C N X
Generic name:
hyoscyamine systemic
Drug class:
anticholinergics/antispasmodics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Entocort EC 7.8 6 reviews for Entocort EC to treat Crohn's Disease Rx C N
Generic name:
budesonide systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
risankizumab 7.4 11 reviews for risankizumab to treat Crohn's Disease Rx N
Generic name:
risankizumab systemic
Brand name:
Skyrizi
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
upadacitinib 8.2 15 reviews for upadacitinib to treat Crohn's Disease Rx N
Generic name:
upadacitinib systemic
Brand name:
Rinvoq
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
mirikizumab Rate Add review Rx N
Generic name:
mirikizumab systemic
Brand name:
Omvoh
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Omvoh Rate Add review Rx N
Generic name:
mirikizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tremfya Rate Add review Rx N
Generic name:
guselkumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Imuran 3.3 6 reviews for Imuran to treat Crohn's Disease Rx D N
Generic name:
azathioprine systemic
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cholestyramine Off-label 8.8 17 reviews for cholestyramine to treat Crohn's Disease Rx C N
Generic name:
cholestyramine systemic
Drug class:
bile acid sequestrants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Cimzia 6.5 4 reviews for Cimzia to treat Crohn's Disease Rx B N
Generic name:
certolizumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
infliximab 5.1 45 reviews for infliximab to treat Crohn's Disease Rx B N
Generic name:
infliximab systemic
Brand names:
Remicade, Inflectra, Renflexis, Avsola, Ixifi, Zymfentra
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
rifaximin Off-label 9.3 7 reviews for rifaximin to treat Crohn's Disease Rx C N
Generic name:
rifaximin systemic
Drug class:
miscellaneous antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Off-label:
Yes
Azasan 10 1 review for Azasan to treat Crohn's Disease Rx D N
Generic name:
azathioprine systemic
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tacrolimus Off-label 6.0 3 reviews for tacrolimus to treat Crohn's Disease Rx C N X
Generic name:
tacrolimus systemic
Drug class:
calcineurin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
cyclosporine Off-label Rate Add review Rx C N
Generic name:
cyclosporine systemic
Drug class:
calcineurin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Inflectra 3.2 13 reviews for Inflectra to treat Crohn's Disease Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Renflexis 5.0 2 reviews for Renflexis to treat Crohn's Disease Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
certolizumab 6.5 4 reviews for certolizumab to treat Crohn's Disease Rx B N
Generic name:
certolizumab systemic
Brand name:
Cimzia
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Amjevita Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Avsola 8.0 3 reviews for Avsola to treat Crohn's Disease Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cyltezo Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Hadlima 6.0 1 review for Hadlima to treat Crohn's Disease Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Hyrimoz Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mycophenolate mofetil Off-label Rate Add review Rx D N
Generic name:
mycophenolate mofetil systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Abrilada Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Hulio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Idacio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ixifi Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
Yuflyma Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yusimry Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Simlandi Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Wezlana Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zymfentra Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
guselkumab Rate Add review Rx N
Generic name:
guselkumab systemic
Brand name:
Tremfya
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Imuldosa Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Otulfi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Pyzchiva Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Selarsdi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Steqeyma Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Yesintek Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Topics under Crohn's Disease

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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