Aminosalicylates are anti-inflammatory agents used to treat inflammatory bowel disease and some forms of arthritis. They work by inhibiting the production of cyclo-oxygenase and prostaglandin, thromboxane synthetase, platelet activating factor synthetase, and interleukin-1 by macrophages so reduces the acute inflammatory response in inflammatory bowel disease.
Production of immunoglobulin by plasma cells is also decreased.
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