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5-aminosalicylates

What are 5-aminosalicylates?

Aminosalicylates are anti-inflammatory agents used to treat inflammatory bowel disease and some forms of arthritis. They work by inhibiting the production of cyclo-oxygenase and prostaglandin, thromboxane synthetase, platelet activating factor synthetase, and interleukin-1 by macrophages so reduces the acute inflammatory response in inflammatory bowel disease.

Production of immunoglobulin by plasma cells is also decreased.

Aminosalicylates are used to treat ulcerative colitis, proctitis and Crohn's disease.

List of 5-aminosalicylates

View by  Generic | Brand
Drug Name Avg. Rating Reviews
mesalamine systemic (Pro)
Brand names: Apriso, Asacol, Asacol HD, Canasa, Canasa Pac, Delzicol, Lialda, Pentasa, Rowasa, Zaldyon
7.1
 425 reviews
sulfasalazine systemic (Pro)
Brand names: Azulfidine, Azulfidine EN-tabs
6.0
 197 reviews
balsalazide systemic (Pro)
Brand name: Colazal
6.5
 37 reviews
olsalazine systemic (Pro)
Brand name: Dipentum
9.7
 4 reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions treated or associated with 5-aminosalicylates:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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