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User Reviews for Sulfasalazine

Also known as: Azulfidine, Azulfidine EN-tabs, Sulfazine

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Sulfasalazine.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Inflammatory Bowel Disease 2 reviews 73 medications
   
10
Crohn's Disease 5 reviews 69 medications
   
9.5
Crohn's Disease, Maintenance 1 reviews 27 medications
   
8.0
Juvenile Rheumatoid Arthritis 2 reviews 162 medications
   
6.0
Rheumatoid Arthritis 24 reviews 345 medications
   
5.8
Psoriatic Arthritis 12 reviews 61 medications
   
5.8
Crohn's Disease, Acute 1 reviews 16 medications
   
4.5
Ulcerative Colitis 11 reviews 96 medications
   
4.5
Summary of Sulfasalazine reviews 58 reviews 6.8

Reviews for Sulfasalazine

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For Rheumatoid Arthritis: "Update from June. My husband has been improving in terms of his Anaemia of Chronic disease on Prednisone 15mg daily. However still on 2 gms of Sulfasalazine he has had Pleuritis for two months and now has Conjunctivitis and .? Scleritis. All of which are listed as side effects of Sulfasalazine. These are his only symptoms associated with RA. While reluctant to reduce the Sulfasalazine we will do so. We increased the Minocycline to 200mg alt days. a few days ago."

DrG2 (taken for 1 to 2 years) August 8, 2017

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For Ulcerative Colitis: "This medicine has completely turned my life around! Just when I was losing hope I started this medication 1000mg 4 times a day. I went from having severe gas pain, blood, mucas, a lot of BM, and uncomfortable distended stomach after I ate to EVERY symptom GONE after the first month of taking this medication! The only side effect I've experienced is the first few days of starting the medicine I had really bad stomach upset but after day 4 my body started to adjust and I had my first normal BM in almost a year! I also get headaches randomly but ibuprofen always knocks it out. Totally worth giving it a shot!"

   
9.0

Anonymous (taken for 1 to 6 months) August 3, 2017

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For Rheumatoid Arthritis: "Was put on sulfasalazine 2 weeks ago! I've had methotrexate...plus injectable meteject...leflunamide & now this traumatizing horrible stuff. Every single DMARD has had horrendous effects on me. Started sulfasalazine 2 weeks ago & have had continual non stop pressure, headaches and sweats, nausea & feel bloody awful.. so so so bad.. I went away for a week on holiday and I've never felt so ill! It completely ruined my family holiday. These headaches are ruining my life! It feels like someone's got a clamp around my head and has turned the heating up to full blast in my bones and body! Not happy at all. :"("

   
1.0

db68 July 23, 2017

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For Crohn's Disease, Maintenance: "I was on sulfasalazine for 25 years until my kidney function decreased, and I had bone marrow suppression. In other words, I became pretty ill. I already had third stage kidney disease from another medication, bipolar. I take Topamax for the migraines.I have gastroparesis and take 5 other medications. I originally started with acute crohn's olitis but have been in remission since taking prednisone & then sulfasalazine"

Anonymous (taken for 10 years or more) July 3, 2017

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For Rheumatoid Arthritis: "I'm a late 50s male recently diagnosed with RA. Thus far, it has not worked at all for me (have "ramped up" over the past two months). To be fair, I was told it could take months before it "kicked in." I'm fairly miserable every day - hands, feet, and jaw, alternating or at the same time. Had no idea how nasty RA is until getting first-hand experience. Fatigue is an issue for me as well, RA or the sulfasalazine? This has been tough as I have always been very active."

   
3.0

Humbled Man June 22, 2017

5 users found this comment helpful.

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For Rheumatoid Arthritis: "My husband has been on Sulfasalazine 2 gms a day since November 2016 for his severe RA. He developed RA in January of last year and was on Methorexate for 8 months when it was discontinued due to severe Bacteriaemia. He is also taking Minocycline. He had a probable flare at the beginning of May this year, six months after starting both drugs. At that time he also developed Atrial Fib that reverted on drugs. He was prescribed Flecainide which he took for two weeks but discontinued it due to side effects. We blamed that for his loss of appetite and weight loss - 36 lbs in six weeks. It's now three weeks since he stopped the heart drug. I'm now thinking it might be the Sulfasalazine. His RA symptoms are gone apart from a little stiffness."

DrG2 June 12, 2017

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For Rheumatoid Arthritis: "I started on 0.5g/day (1 tab) and increased the dose weekly until I reached a max dose of 3g/day (6 tabs). At first I thought it wasn't working at all because my pain never improved, but eventually I realised that brand new symptoms were presenting in new joints and that I was now also experiencing awful muscle spasm (in my calves, fingers and toes) - I had never had this problem before. My fatigue also became more and more severe... Eventually, nearly 4 months after starting treatment, I stopped this awful drug.... Sadly, 1 month later, I am still struggling with the after effects. What a terrible terrible drug this is."

   
1.0

IssyB (taken for 1 to 6 months) May 25, 2017

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For Ulcerative Colitis: "It wasn't helpful at all very useful."

   
3.0

Rita Moore April 30, 2017

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For Crohn's Disease: "Have been on several medications over the years. This being one of them. Was taken off about 9 years ago. Went to many others over next 6 years. Was put on lialda 2 years ago with worsening symptoms. More pain and distended belly. Went to emergency room for 4 the time in three months. Asked my doctor about putting me back on this. I shouldn't be having this many issues. Its been 2 days on salfasazine cypro, flagyl and zofran. Stomach is half its size. Way less pain and eating chicken and stars soup. Yeah."

   
9.0

Amrhymer March 25, 2017

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For Psoriatic Arthritis: "Been a psoriatic arthritis sufferer these last twenty years. My flare ups are dreadful. After taking them for just two weeks symptoms are abated; it really works for me despite convincing my new GP I knew what I was on about! Methotrexate was awful. No side effects with SULFASALAZINE with me. After three months no pain at all....but one needs to drink lots of water. I've had periods on and off this drug, all due to flare ups..."

   
9.0

Mumswallet (taken for 10 years or more) March 20, 2017

9 users found this comment helpful.

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Sulfazine (sulfasalazine) for Rheumatoid Arthritis: "Nasty stuff. First had extreme tiredness, then stomach pain, diarrhea, headache, fever, chills, rash. Went to emergency. Was on it total of 3-1/2 wks. Stopped it two days ago, still not well. Maybe go back to methotrexate."

   
1.0

Tdcime February 26, 2017

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For Psoriatic Arthritis: "Trialled this medicine for Psoriatic arthritis for approx 6 months in combination with Methotrexate and Hydroxychloroquinine. While no major side effects there was no clinical efficacy either so therapy was discontinued."

   
1.0

Aussie Beau (taken for 1 to 6 months) February 5, 2017

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For Ulcerative Colitis: "I have taken sulfasalazine for 40 yrs. It worked OK on my u.c. until I had a flair up. I would have to take 8 pills a day for months. My urine was always orange and Medicaid only paid for a limited number of pills per month. After much research this year, I tried a probiotic for my gut. I found that one probiotic (45 billion active cultures) a day did a better job of keeping the u.c. at bay. I can eat vegetables I couldn't before. I have less gas and more normal bowel movements. I quit taking the sulfasalazine because it interfered with the probiotic. I haven't had a problem these last 6 months even with excessive stress."

   
6.0

K.D.L. February 1, 2017

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For Crohn's Disease: "My doc said, "let's try sulfafalazine ".So we did, and I've been on 1000mg three times a day. Don't even realize I have Crohns disease most of the time. (Recommended). There is that other part where everyone gets a different reaction thoe..... ."

   
10

Mike $321 February 1, 2017

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For Ulcerative Colitis: "It helped a little for a couple months but didn't have as much effect as me and my GI specialist had hoped. After the couple months it became completely uneffective."

   
1.0

Anonymous (taken for 1 to 6 months) January 20, 2017

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For Psoriatic Arthritis: "Was diagnosed with psoriatic arthritis at 28 years old. In a span of about 8 weeks I had 3 joint flare ups. At first I just thought I jammed a few few fingers, but after having the same issue in my toe (and the fact they weren't healing) I finally saw a doctor who recommended a rheumatologist and I was diagnosed. Took a while to take effect, but I started noticing a difference at 10 weeks. After 10 weeks, sulfasalazine plus 660 mg naproxen sodium was enough for my fingers to feel 85% normal. After 4 months my joints felt 85% on sulfasalazine alone. By 6 months it's as if I don't have arthritis at all. Truly miracle drug."

   
10

Shed987 (taken for 6 months to 1 year) January 13, 2017

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For Rheumatoid Arthritis: "Initially caused severe headaches upon waking. The headaches responded well to Tylenol. Took months to become effective at all and after that my rheumy doubled my dose which took even more months. Total time to achieve a tolerable level of inflammation was 7 months. I finally feel like a more "normal" person again. It is not 100% effective but I am satisfied as I do not need to take anything else like an NSAID or other pain meds. any more. I'm glad I didn't give up on it as it is working and is considered one of the more benign DMARDs available. I suffer from inflammatory arthritis (nonspecific/not RA). Check into turmeric (golden paste) to help with inflammation. Praying for a cure for all!"

Pusheen (taken for 6 months to 1 year) December 17, 2016

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For Rheumatoid Arthritis: "I was diagnosed with RA when I was 10 years old. I was prescribed methotrexate originally and that worked well. But when I reached 21, I wanted to come off of it because I wanted to be able to consume alcohol. I was then prescribed sulfasalazine and found that this worked just as well as methotrexate. The only downfall was how long it took to kick in and relieve my symptoms. After taking sulfasalazine for a little over a year, I went into remission for 3 years. But this week my jaw is very stiff and hurts pretty bad so I started back up on sulfasalazine (2 pills in the morning, 2 pills at night). I have no side effects. For those who get nausea from sulfasalazine-folic acid really helps with that. I highly recommend this medication."

   
10

caseey14 December 11, 2016

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For Juvenile Rheumatoid Arthritis: "Sulfasalazine initially caused extreme headaches upon waking, extra strength acetametaphine worked for those. It took months to begin to work and I eventually got to 4 pills per day. It took an extra six months for it to work well. I still have low grade inflammation but at least I am not miserable anymore, can sleep through the night and get up fairly well. So it did work but for me it took a super long time to do so. My CRP dropped to normal (2 from 16.5) well before I felt close to normal."

   
7.0

Pusheen (taken for 6 months to 1 year) December 11, 2016

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For Rheumatoid Arthritis: "I've been on sulfasalazine for just about 8 months. I started it as they advise--increasing dose each week until up to 4 per day. (for RA) It began working fairly well after a few weeks, however, by the time I got up to the full dose, I began to have a feeling of something stuck in throat-almost unable croak out a sound.I'm a professional singer/musician, so this was impossible. I immediately cut back, and it got better. I really wanted this to work, it's cheap and one of the safest RA meds. Anyway, I was able to totally control my RA with 1 sulfasalazine and 2 plaquenil daily.Still hoarse/throat problems, and now fingers are peeling and sore. Time to switch to methotrexate to see if it gets better. :("

   
9.0

rebbie55 September 27, 2016

18 users found this comment helpful.

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For Rheumatoid Arthritis: "I have been on these meds for 6 weeks now. Started with one pill a day, then increased weekly to four pills a day. It has greatly helped with my pain. I'm sleeping better at night and especially within the last week, have been able to go about life almost how I did prediagnosis. So for that part - I would recommend giving it a go. As for side effects, I've been fortunate enough to not experience any type of stomach upset or headaches or anything like that. I have however been losing alot of hair. I can run my hand through very lightly, no tugging whatsoever, and end up with about 20 strands. I can run my hand through continually like this and the same thing happens. No pain from pulling, just falling out :( Choosing to tough it out for now"

   
6.0

australiankitten June 9, 2016

34 users found this comment helpful.

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For Rheumatoid Arthritis: "I don't recommend this med... Just two days of taking this and a severe headache every time. Gonna see my rhumy to change this med.."

   
2.0

BAD MED (taken for less than 1 month) May 1, 2016

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For Rheumatoid Arthritis: "I have only been on this med for 4 months. It has helped with my stiffness. My body would become so stiff, felt like I had pre death rigormortis... especially after sitting for any length of time. Getting up from a sitting position was extremely painful and awkward. My only complaint about the med is that it is to large for me to swallow. I take 3 per day, and I am fearful that I will choke on them. They scrape my throat and esophagus when I take them. Wish they would change the shape and coat them to make them easier to take."

   
8.0

mygoldens April 25, 2016

42 users found this comment helpful.

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For Psoriatic Arthritis: "I was on sulfasalazine after being diagnosed with PSA. My first arthritis medication. I was also experiencing reactive arthritis when first diagnosed. I started at 1 tablet 2 times a day. I had some quite adverse reactions to start, trouble sleeping and nausea. Rheumatologist suggested humeria. After reading up on humeria I decided it was worth trying to soldier through a longer trial period with sulfasalazine before switching, eating plain food etc. to minimise impacts of side effects. So glad I did. Now at 4 tabs/day. All the side effects are now gone and I can eat normally. Sulfasalazine has reduced joint inflammation to the point that I can exercise. I recommend giving sulfasalazine side effects a bit of time to equalize."

   
8.0

Hilara April 7, 2016

34 users found this comment helpful.

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For Rheumatoid Arthritis: "Started on sulfasalazine three months ago. First four weeks difficult as experienced headache, palpitations and felt exhausted. I also had severe mouth ulcers and required antibiotic therapy. Found increasing tabs weekly too intense so reduced increase to four weekly and found my body tolerated increase better. Now on two am and one pm and starting to see improvement in swelling and flare. Noted once flare starts it was time to increase dose. Started feeling aches all over this weekend so plan to increase to two am and two pm. Will update on progress. Nb in uk"

   
5.0

Toli (taken for 1 to 6 months) February 28, 2016

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