Sulfasalazine and Ringing In Ears: What Users Say

• kar...
• April 11, 2010

Sulfasalazine for Rheumatoid Arthritis "I have had a small improvement with sulfasalazine, but unfortunately, I started having severe ringing in the ears after 6 months. Also, it gave me pain in my Achilles tendon and calves at night. Keep in mind that I had the pain side effect also with cholesterol medications, but not the ringing in the ears."

• Mar...
• Taken for 1 to 6 months
• August 26, 2021

For Rheumatoid Arthritis "I have been dealing with RA (ankylosing spondylitis) for about 30 years. My medications have run the gamut from A to Z. The last medicine was Humira, which ended up giving me Hodgkin's lymphoma and 6 months of chemotherapy to put it in remission. I am now back to square one and was prescribed sulfasalazine. A few weeks after taking it, I noticed constant nausea, ringing in my ears, hair loss, and constipation with no relief for my swollen knees. I am done being a guinea pig for these pharmaceutical companies and am looking at a natural approach using a strict diet, turmeric, and other natural compounds to manage this. No more science experiments for me."

• Hur...
• Taken for 1 to 6 months
• January 6, 2019

For Rheumatoid Arthritis "I started taking sulfasalazine (SZS) with Plaquenil 2 months ago for RA. Immediately felt dizzy, confused, nosebleed, and depression, and also severe vision changes. Bi-weekly blood draws were a total painful waste of time. Then began a very intense ringing in my ears. Discontinued Plaquenil twice a day, and dropped the SZS from 4 per day to 3. I did get some relief from RA, but far from worth the suffering of the severe side effects. Ringing in my ears continued, especially bad in the mornings. Stopped SZS 2 days ago, and ears still ringing like crazy. I hope this stops soon as I am almost crazy with it. Both drugs are very nasty, and I will never again take either of these drugs. Appointment with rheumatologist as soon as the ringing stops. She suggested an appointment with an audiologist to address the tinnitus. I know it is the SZS causing it. Going to try a different treatment, might as well go all the way at this point. Not ruling out Humira or another biologic."

• Ven...
• Taken for less than 1 month
• June 6, 2024

For Rheumatoid Arthritis "In the beginning, I had ringing in ears, numbness and tingling in lower extremities, headaches while taking 2 tabs daily - but the swelling and pain of RA decreased significantly. My doctor said he had never heard of this. Well, it's clearly stated in the side effects. I wanted to try again, so I am on 1 tab daily. I sometimes have upper epigastric pain. We will see if I'm able to progress to 2 tabs daily."

• toc...
• Taken for 2 to 5 years
• August 7, 2012

For Psoriatic Arthritis "I too am using sulfasalazine for psoriatic arthritis, and it has helped somewhat, and I too have ringing in my ears. Suffice to say, it has helped, so I do recommend it."

• Nan...
• Taken for 10 years or more
• May 25, 2023

For Rheumatoid Arthritis "I experienced dizziness, nausea, and tinnitus. It has helped my arthritis, but the side effects are making me want to discontinue taking it."

• Anonymous
• Taken for 2 to 5 years
• June 22, 2024

For Rheumatoid Arthritis "After taking this med for four years I’m having: digestive distress, itchy skin and rashes, cough and tightness in my chest, losing hair, weakness and extremely tired, tinnitus."

• Pam...
• Taken for 6 months to 1 year
• July 23, 2023

For Rheumatoid Arthritis "Dizziness, ringing in ears, insomnia from time to time."