Sulfasalazine Drug Interactions
A total of 294 drugs (1431 brand and generic names) are known to interact with sulfasalazine.
- 50 major drug interactions (249 brand and generic names)
- 223 moderate drug interactions (1089 brand and generic names)
- 21 minor drug interactions (93 brand and generic names)
Check for interactions with sulfasalazine
Common medications checked in combination with sulfasalazine
- Aspirin Low Strength (aspirin)
- Celebrex (celecoxib)
- Cymbalta (duloxetine)
- Enbrel (etanercept)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Humira (adalimumab)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Plaquenil (hydroxychloroquine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
sulfasalazine disease Interactions
There are 11 disease interactions with sulfasalazine which include:
- Intestinal Obstruction
- Urinary Obstruction
- Hematologic Toxicity
- Hypersensitivity Reactions
- Liver Disease
- Porphyria
- Renal Dysfunction
- Colitis
- Renal Dysfunction
- Folate Deficiency
- Crystalluria
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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