Generic name: Infliximab-dyyb [ in-FLIKS-e-mab ]
Drug classes: Antirheumatics, TNF alfa inhibitors

Medically reviewed by Drugs.com. Last updated on Mar 30, 2024.

Uses of Infliximab-dyyb:

• It is used to treat Crohn's disease.
• It is used to treat some types of arthritis.
• It is used to treat plaque psoriasis.
• It is used to treat ankylosing spondylitis.
• It is used to treat ulcerative colitis.
• It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Infliximab-dyyb?

• If you are allergic to infliximab-dyyb; any part of infliximab-dyyb; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you are allergic to mouse proteins, talk with the doctor.
• If you have heart failure (weak heart).
• If you are taking any of these drugs: Abatacept or anakinra.
• If you are using another drug like this one. If you are not sure, ask your doctor or pharmacist.

This is not a list of all drugs or health problems that interact with infliximab-dyyb.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take infliximab-dyyb with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Infliximab-dyyb?

• Tell all of your health care providers that you take infliximab-dyyb. This includes your doctors, nurses, pharmacists, and dentists.
• Have blood work checked as you have been told by the doctor. Talk with the doctor.
• Low blood cell counts have happened with infliximab-dyyb. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Sometimes, these have been deadly. If you have questions, talk with the doctor.
• You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
• Talk with your doctor before getting any vaccines. Use of some vaccines with infliximab-dyyb may raise the chance of an infection.
• Do not get a weakened bacteria like BCG for bladder cancer while you use infliximab-dyyb. Talk with your doctor.
• Have your skin checked. Tell your doctor if you have any skin changes like a new wart, skin sore or reddish bump that bleeds or does not heal, or a change in the color or size of a mole.
• If you have had hepatitis B before or carry the virus, infliximab-dyyb can cause the virus to become active. This can lead to very bad and sometimes deadly liver problems. You will be tested for hepatitis B before starting infliximab-dyyb. You will need to watch for signs of hepatitis while taking infliximab-dyyb and for several months after stopping it. Talk with your doctor.
• Rarely, people using drugs like this one have had nervous system problems. Sometimes, these problems have not gone away. Call your doctor right away if you have a burning, numbness, or tingling feeling that is not normal; change in eyesight; dizziness; seizures; or weakness in your arms or legs.
• Liver problems have rarely happened with infliximab-dyyb. Sometimes, this has been deadly. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
• Abnormal heartbeats, heart attacks, high or low blood pressure, and strokes have happened during and within 24 hours after the infusion. Sometimes, heart attacks have been deadly. Loss of eyesight has also happened during and within 2 hours after the infusion. Talk with the doctor.
• If you are 60 or older, use infliximab-dyyb with care. You could have more side effects.
• Use with care in children. Talk with the doctor.
• If using in a child, make sure your child is up to date with all vaccines.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
• If you used infliximab-dyyb during pregnancy, tell your baby's doctor. You will need to discuss the safety and timing of certain vaccines with the doctor.

How is this medicine (Infliximab-dyyb) best taken?

Use infliximab-dyyb as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• It is given as an infusion into a vein over a period of time.
• This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take infliximab-dyyb.

What do I do if I miss a dose?

• Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
• Signs of lupus like a rash on the cheeks or other body parts, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs.
• Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
• Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
• Redness or swelling where the shot is given.
• Any unexplained bruising or bleeding.
• Pale skin.
• Loss of eyesight.
• A skin lump or growth.
• Vaginal bleeding that is not normal.
• Fast or slow heartbeat.
• Red scaly patches or bumps that are pus filled.
• Fever, chills, itching, hives, chest pain or pressure, or shortness of breath when drug is given. Other drugs may be given to avoid these.
• Call your doctor right away if you have a swollen gland, night sweats, shortness of breath, or weight loss without trying.
• Heart failure has happened with infliximab-dyyb, as well as heart failure that has gotten worse in people who already have it. Tell your doctor if you have heart disease. Call your doctor right away if you have shortness of breath, a big weight gain, a heartbeat that is not normal, or swelling in the arms or legs that is new or worse.

Related/similar drugs

Entyvio, Otezla, Sotyktu, Cimzia, prednisone, naproxen, methotrexate, dexamethasone, hydrocortisone, hydroxychloroquine

What are some other side effects of Infliximab-dyyb?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Headache.
• Upset stomach or throwing up.
• Stomach pain or diarrhea.
• Feeling tired or weak.
• Flushing.
• Signs of a common cold.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Infliximab-dyyb?

• If you need to store infliximab-dyyb at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
• This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time infliximab-dyyb is refilled. If you have any questions about infliximab-dyyb, please talk with the doctor, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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