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Rayos

Generic name: prednisonePRED-ni-sone ]
Drug class: Glucocorticoids

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 3, 2023.

What is Rayos?

Rayos is a corticosteroid that reduces inflammation in the body, and also suppresses your immune system.

Rayos is used to treat many different conditions such as hormonal disorders, skin diseases, arthritis, lupus, psoriasis, allergic conditions, ulcerative colitis, Crohn's disease, eye diseases, lung diseases, asthma, tuberculosis, blood cell disorders, kidney disorders, leukemia, lymphoma, multiple sclerosis, organ transplant rejection, swelling from a brain tumor or injury.

Rayos may also be used for purposes not listed in this medication guide.

Warnings

You should avoid taking Rayos if you have a fungal infection that requires oral antifungals. Topical antifungals may not be an issue, but always let your doctor know what medicines you’re taking before starting Rayos.

Corticosteroid medication can weaken your immune system, making it easier for you to get an infection. Avoid being near people who are sick or have infections. Do not receive a "live" vaccine while using prednisone.

Call your doctor at once if you have shortness of breath, severe pain in your upper stomach, bloody or tarry stools, severe depression, changes in personality or behavior, vision problems, or eye pain.

You should not stop using Rayos suddenly. Follow your doctor's instructions about tapering your dose.

Before taking this medicine

You should not use Rayos if you are allergic to prednisone, or if you have a fungal infection anywhere in your body.

Corticosteroid medication can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have. Tell your doctor about any illness or infection you've had within the past several weeks.

To make sure Rayos is safe for you, tell your doctor if you have ever had:

Long-term use of corticosteroids may lead to bone loss (osteoporosis), especially if you smoke or drink alcohol, if you do not exercise, or if you do not get enough vitamin D or calcium in your diet.

It is not known whether prednisone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using Rayos.

How should I take Rayos?

Take Rayos exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Rayos is taken daily or every other day, depending on the condition being treated. You may need to take the medicine at a certain time of day. Follow your doctor's instructions about when and how often to take this medicine.

Take with food if Rayos upsets your stomach.

Swallow the Rayos delayed-release tablet whole and do not crush, chew, or break it.

Prednisone can weaken (suppress) your immune system, and you may get an infection more easily. Call your doctor if you have signs of infection (fever, weakness, cold or flu symptoms, skin sores, diarrhea, frequent or recurring illness).

If you have major surgery or a severe injury or infection, your prednisone dose needs may change. Make sure any doctor caring for you knows you are using this medicine.

If you use this medicine long-term, you may need medical tests and vision exams.

In case of emergency, wear or carry medical identification to let others know you use a steroid.

You should not stop using Rayos suddenly. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

High doses or long-term use of Rayos can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What to avoid

Do not receive a "live" vaccine while using Rayos. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using steroid medicine.

Avoid drinking alcohol.

Rayos side effects

Get emergency medical help if you have signs of an allergic reaction to Rayos: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

Prednisone can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common Rayos side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rayos?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines. Many drugs can interact with prednisone, especially:

This list is not complete and many other drugs may interact with prednisone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Popular FAQ

The starting dose of prednisone may be between 5 mg to 60 mg per day. A dose above 40 mg per day may be considered a high dose. However, everybody responds differently to prednisone, so what might be a high dose depends on the person and the condition. Continue reading

Although there is no direct drug interaction between prednisone and alcohol, mixing them together is not a good idea because some of the effects of alcohol and the side effects of prednisone are similar, so taking both at the same time can increase the risk of these side effects occurring. Continue reading

There is no set limit on how long you can safely take prednisone. It depends on the dose of prednisone and the condition being treated. It may be prescribed short term or long term. The dosage will be adjusted or stopped based on your response or lack of response to the medication. Continue reading

Prednisone first came onto the market over sixty years ago and is still going strong. But did you know that this common drug used for a variety of different conditions also has some pretty serious side effects as well? Continue reading

The best prednisone taper will depend upon how long you have been taking the medicine, your dose, and why you are being treated. If you've been treated with a high dose of prednisone, or taken it for more than a few weeks, you will need to slowly stop your medicine, usually over a period of days, weeks or months. Your healthcare provider will determine your prednisone tapering schedule. Continue reading

Prednisone usually works very quickly, within a few hours to days of taking the first dose depending on the condition you are treating. If the prescribed dose of prednisone is effective at reducing your inflammation, then you may notice an effect within hours. Continue reading

It's best to take prednisone as a single dose once a day straight after breakfast. For example if your dose is 30mg daily, it's usual to take 6 tablets (6 x 5mg) all at the same time after breakfast. Continue reading

In general, you could expect a dose or prednisone to stay in your system for 16.5 to 22 hours based on a half life of 3 to 4 hours. It usually takes around 5.5 half lives for a drug to be completely eliminated from your system. Continue reading

Common antidepressants used for orthopedic pain relief may include SSRIs like fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft), SNRIs such as duloxetine (Cymbalta), or tricyclic antidepressants (TCAs) like amitriptyline (Elavil) or nortriptyline (Pamelor). Continue reading

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Rayos only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.