Medically reviewed on August 22, 2018.
Applies to the following strengths: 200 mg/mL; 120 mg; 400 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Systemic Lupus Erythematosus
10 mg/kg IV at 2-week intervals for the first 3 doses and at 4-week intervals thereafter.
-Infuse over a 1-hour period.
-Consider premedication including an antihistamine, with or without an antipyretic, before the infusion.
Use: Treatment of adult patients with active, autoantibody-positive, systemic lupus erythematosus (SLE) who are receiving standard therapy.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Data not available
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Data not available
-Do not administer intravenous push or bolus.
-Refrigerate, protect from light.
-Do not freeze.
-Avoid exposure to heat.
-The total time from reconstitution to completion of infusion should not exceed 8 hours
-After reconstitution, if not used immediately, protect from direct sunlight, and refrigerate.
-After final dilution in sodium chloride 0.9% solution, may store refrigerated or at room temperature.
Reconstitution/preparation techniques: The manufacturer product information should be consulted.
-Not compatible with 5% dextrose
-Do not infuse concomitantly in the same intravenous line with other agents.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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