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User Reviews for Azathioprine

Also known as: Imuran, Azasan

Azathioprine has an average rating of 6.0 out of 10 from a total of 106 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 34% reported a negative effect.

Condition Avg. Rating Reviews Compare
Ulcerative Colitis  
6.7
22 reviews 75 medications
Systemic Lupus Erythematosus  
5.4
22 reviews 101 medications
Crohn's Disease, Maintenance  
6.1
18 reviews 26 medications
Crohn's Disease  
5.1
12 reviews 19 medications
Rheumatoid Arthritis  
3.3
8 reviews 362 medications
Autoimmune Hepatitis  
9.0
6 reviews 2 medications
Crohn's Disease, Acute  
4.3
4 reviews 32 medications
Myasthenia Gravis  Off-label
7.7
3 reviews 8 medications
Multiple Sclerosis  
4.5
2 reviews 98 medications
Inflammatory Bowel Disease  
5.0
2 reviews 69 medications
Renal Transplant  
10.0
2 reviews 7 medications
Pemphigus  Off-label
7.0
1 reviews 17 medications
Atopic Dermatitis  
7.0
1 reviews 244 medications
Granulomatosis with Polyangiitis  
6.0
1 reviews 5 medications
Behcet's Disease  Off-label
8.0
1 reviews 1 medications
Eczema  Off-label
9.0
1 reviews 248 medications
Summary of Azathioprine reviews 6.0 106 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Azathioprine

Anonymous February 2, 2012

Imuran (azathioprine) for Autoimmune Hepatitis: “I have chronic autoimmune hepatitis and have been taking Imuran for four years. It has prevented further flare ups (which I have taken as much as a year to recover from) it enables me to live my life feeling well with mild side effects (some nausea).”

8 / 10
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Karagg February 26, 2020

Imuran (azathioprine) for Systemic Lupus Erythematosus: “I was prescribed imuran for systemic lupus. I took the medicine for about one month. I had a terrible “allergic” reaction- I was hospitalized for several days. High fever, liver, joint pain. It is my understanding that Imuran can cause an allergic reaction (it was not a unique reaction to me). I have since learned (from a doctor at the John Hopkins Lupus Center) that there is a test to determine if you will tolerate Imuran. The test checks the level/presence of an enzyme necessary for the body to “process” or tolerate Imuran. I would ask your doctor about the test for Imuran tolerance before starting Imuran - my allergic reaction was very bad. I am not an alarmist and I understand that Imuran is an effective medicine for many people. However, I wish I had known that a test was available to determine if a patient will tolerate Imuran as this would have been extremely helpful and I could have avoided a very serious allergic reaction to Imuran.”

1 / 10
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Living in the Bathroom August 19, 2011

Imuran (azathioprine) for Ulcerative Colitis: “Have had ulcerative colitis for 26 years. Started Imuran after a flare up and within 1 week I thought it was a miracle and still am going to the bathroom 2 x a day and sleep all night. I worry about the side effects but I have a life again for now. Thanks to Imuran.”

9 / 10
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preocupada · Taken for 1 to 6 months May 6, 2012

Imuran (azathioprine) for Systemic Lupus Erythematosus: “Imuran greatly improved my systemic lupus erthematous (SLE) symptoms. I have neurological involvement and before this medicine my right foot was paralyzed. I can now walk thanks to this. I had blood work and all my values are normal now which was not the case before. I do not have any side effects either. It has been a lifesaver for me.”

10 / 10
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Tttttttt 100 · Taken for 6 months to 1 year January 13, 2016

For Ulcerative Colitis: “I was extremely sick for over 2 years and refused to take this medication due to how scared I was of the side effects. I decided it was worth the risk and started taking it. I was tired a lot the first month but after one month I felt so good! I have been on it now for about 6 months and I am doing wonderful. I think we hear a lot of the bad things online because the people who these drugs work for are out enjoying life. I hope I give some of you peace of mind.”

9 / 10
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Anonymous January 28, 2011

Imuran (azathioprine) for Ulcerative Colitis: “Have been using for over two years after several episodes of prednisone. Have been almost completely free of symptoms and have no obvious side effects. I only use the bathroom once a day and stools are generally well formed. No diarrhea at all. Can eat and drink normally (including roughage) but did have some pain after eating too much corn on the cob.”

10 / 10
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Mary · Taken for 6 months to 1 year December 24, 2018

Imuran (azathioprine) for Systemic Lupus Erythematosus: “I've been on Imuran for 6 months and it hasn't helped at all. In fact, I'm sicker now on it. The biggest side effects for me are loss of appetite, nausea and diarrhea. The diarrhea is horrible. I go at least 10 times a day and nothing helps. I'm exhausted from being so dehydrated and malnourished. When I see my rheumatologist in a week, I'm begging him to try anything else but Imuran. I can't handle it anymore.”

1 / 10
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Ccm · Taken for 10 years or more December 6, 2020

Imuran (azathioprine) for Autoimmune Hepatitis: “I have been on Azathioprine for over 20 years, along with Prednisone when I have a flare of Autoimmune Hepatitis. A couple times the Dr tried to lower my doses and each time I flared. Azathioprine has been a life saver.”

10 / 10
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Mara · Taken for 10 years or more May 21, 2020

Imuran (azathioprine) for Systemic Lupus Erythematosus: “I have been taking Imuran for over 40 years since I was diagnosed with Lupus. My Lupus have been in remission for over 40 years. I have had a kidney transplant for over 30 years ( failure due to my Lupus). I am strong believer by taking the Imuran my Lupus being in remission and having my transplant for so many years is part of the reason for taking Imuran.”

10 / 10
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Anonymous August 13, 2008

Imuran (azathioprine) for Eczema: “Before taking imuran, I was riddled with ezcema from top to toe, bleeding open sores, constantly on antibiotics and cortizone tablets and tablets for depression. It was a vicious cycle that lasted for approximately 3 years. Before this I only had mild ezcema, which I had for 15 years, treated with cortizone creams. Imuran was prescribed by an allergist and immunoligist. At first I took it with cortizone tablets and then after about 2 - 3 months I was only taking Imuran. I have never felt better. I only have a problem with my eyelids now, but this I can handle. I have been on Imuran now for just over a year and fortunately have had very few side effects. ”

9 / 10
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BB1217 March 27, 2014

Imuran (azathioprine) for Systemic Lupus Erythematosus: “I'm a women age 39. I've been on Imuran for over 4 yrs. Before taking Imuran I was on methotrexate and Lyrica which I had EVERY SIDE EFFECT to. But when I switched medicines and began the Imuran it was very helpful! I could tell a big difference in how I felt. I also have fibromyalgia and rheumatoid arthritis as well. Over time and up to this point I'm feeling I need something stronger or even different. I can't tell that I have any known side effects from Imuran. Doctor suggested I try Benlysta. I'm scheduled to start that in two weeks! I'm very nervous because of some of the side effects but you never know until you try! Hope this was helpful! Best of luck!”

6 / 10
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fluffy · Taken for 10 years or more March 2, 2019

Imuran (azathioprine) for Ulcerative Colitis: “I have been on Imuran for over 10 years now. I am now going through my first flareup. I still take it along with a diarrhea med. The imuran has been a life saver for me. Fatigue is normal, have not had to stop any activity. We ride 4 wheelers, drag race, etc. I love the medicine.”

8 / 10
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Ruby · Taken for less than 1 month January 14, 2020

Imuran (azathioprine) for Systemic Lupus Erythematosus: “So, I’m on a few days on Imuran for SLE. The first day, was okay for me.. but, then the days after that, I started getting headache, feeling nausea and on and off diarrhoea. I also don’t feel hungry nor full. Just average basically, all the time. I also noticed I started losing some weight. Not, sure what will happen in the future. Just hoping for the best. ”

6 / 10
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Southern Girl May 27, 2011

Imuran (azathioprine) for Ulcerative Colitis: “Wonderful medicine. I was extremely sick, went 20 times to the bathroom in 8 to 9 hours, was really sick, finally gave in to start this medicine with the rest I had been taking. Within 5 hours everything slowed down. I felt like a new person. But sad to say it was short lived. I started reacting 2 to three days in and the reactions got worse. Had to stop taking it.”

9 / 10
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SueQ · Taken for less than 1 month August 16, 2019

Imuran (azathioprine) for Crohn's Disease: “Was prescribed Imuran as part of combination therapy with Inflectra after a bad flare of Crohn's that landed me in hospital for 2 weeks. I started taking 1 tablet a day, increased to 2 after a week then 2 1/2 after another week. Once I got to the full dose I started to notice some stomach upset and after a week I started vomiting profusely and was bed ridden for 3 days. Also experienced hair loss. My GI told me to stop taking it for now. Sure hope he has another idea as clearly I can’t tolerate Imuran. I felt immediately better after stopping the drug. Good luck to anyone battling this horrible disease!”

1 / 10
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Braeden2748 December 24, 2015

Imuran (azathioprine) for Ulcerative Colitis: “It is a miracle drug! After about 2 months my stools were becoming well formed but not back to the usual stool! I only go once a day and it really is amazing! Although the risks seem huge I just look at it as though without imuran I could be a lot worse!”

9 / 10
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small town mom · Taken for less than 1 month May 28, 2014

Imuran (azathioprine) for Systemic Lupus Erythematosus: “After about 2 weeks into the medicine, I started vomiting severely whenever I took this medication. Ended up in the hospital. I tried this medication again several years later and immediately started vomiting severely. I had to go by ambulance to the emergency room because I could not go by car. I would use extreme caution when first starting this medication because apparently it can cause severe side effects.”

1 / 10
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RjS30 · Taken for 10 years or more September 27, 2017

Imuran (azathioprine) for Crohn's Disease, Maintenance: “I was diagnosed with Crohn's 28 years ago and have been on multiple medications over the years. I had a flare up in January of 2000 after being admitted to the hospital for a failing appendix. That is where I met my current Gastro Doctor. I was put on Imuran with a side of Asacol, but was taken off the Asacol around 7 years ago. I have been taking 100mg of Imuran for 16 years with virtually no side effects and haven't had one flare up to speak of since 2000. I know everyone is different, but Imuran has been super good to me!”

9 / 10
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MySonhasCrohnsDisease · Taken for 6 months to 1 year January 8, 2016

Imuran (azathioprine) for Crohn's Disease, Maintenance: “Our son was very sick for a year before being diagnosed with Crohns Disease, at his worst he was 62 lbs and 12 years old! The poor sweet thing was withering away to nothing! Every bone in his body stuck out It was a terrible time for the entire family to see such a sweet soul struggle so badly. Once we got the diagnosis of Crohns via biopsy and scope his Dr put him on Imuran. 7 months later he now weighs 78lbs and grew almost an inch! He is in remission!!!!!!!!!!!! We are so thankful for this prescription!”

9 / 10
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MI mom February 18, 2016

Imuran (azathioprine) for Rheumatoid Arthritis: “The first two-three weeks were fine. Then I started experiencing a bad headache, the next two days fever and chills. The next evening, severe chills, weakness, dizziness, raging fever (up to 104.3) and began throwing up. It was the worst I've ever felt in my life (and that includes a hospitalization in ICU when first diagnosed). I was on the verge of calling 911. However, it eventually passed (as the medicine worked its way out of my system) and the fever subsided. My Rheumatologist ran a complete series of blood work and she said that I had an allergic reaction. Prior to starting Imuran, I had been tested for liver compatibility and the results showed that I would have no issues so I proceeded. Proceed w/extreme caution.”

1 / 10
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TEP August 27, 2009

Imuran (azathioprine) for Myasthenia Gravis: “Been on Imuran 6 months and find it very helpful for my ocular symptoms and moderately helpful for my generalized Myasthenia Gravis symptoms (fatigue and weakness). So far normal hemograms, hepatic function tests and renal/chem-7 results.”

8 / 10
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christie07 April 29, 2019

Imuran (azathioprine) for Inflammatory Bowel Disease: “Shortly after commencing Imuran at a low dose (50mg/day) I developed a severe & persistent headache and also felt very tired and listless. One week later everything got a lot worse: within 24 hours of commencing the higher dosage (100mg/day) I began to feel extremely nauseous, and about a hour later non-stop vomiting commenced. I couldn't even swallow a mouthful of water without bringing it up almost immediately. That night all the joints in my body began to swell up and become very painful. By 3am I could barely walk, and by 7am my husband had to call in emergency services: my BP had dropped to 56/40, so I was immediately taken to hospital where I was treated with copious amounts of IV fluids, anti-emetics and high doses of corticosteroids. Over the next few days I very gradually began to improve & was discharged from hospital 6 days later, but it took many weeks before I was anywhere near back to normal.”

1 / 10
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Anonymous · Taken for 6 months to 1 year May 2, 2013

Imuran (azathioprine) for Ulcerative Colitis: “Imuran seemed to help for a few months but after prolonged use it weakened my immune system too much. I started getting colds about every three weeks. Which made me feel run down and tired more so than just having colitis alone, but it did at least calm my symptoms for a while.”

5 / 10
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Anonymous · Taken for 1 to 2 years November 7, 2012

Imuran (azathioprine) for Rheumatoid Arthritis: “I was on a steroid previously however due to the fact that I was constantly getting bacterial & viral infections and putting on a lot of weight, the doctor took me off the steroid and prescribed Imuran. So far it is working out better than the steroid.”

8 / 10
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Tomh219 · Taken for 1 to 2 years February 23, 2014

Imuran (azathioprine) for Ulcerative Colitis: “Azathioprine worked well to reduce my ulcerative colitis symptoms and had zero noticeable side effects. The required frequent blood tests were a hassle and it did lower my white count significantly. In the end, the medicine was not sufficient to manage my condition and we added an anti-TNF to it. Once that was ramped up I discontinued azathioprine since it added nothing to the anti-TNF.”

8 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.