Azathioprine for Inflammatory Bowel Disease User Reviews
Brand names: Imuran, Azasan
- Jun...
- Taken for 6 months to 1 year
- February 15, 2018
"I have Crohn's, but it is in my small intestine (not terminal ileum this time) and worse in my mouth. Most of the drugs used (except steroids, which can only be used for a short period of time) are mainly for the terminal ileum and colon and therefore do nothing for my problem. Worse, Entyvio didn't help and made the mouth ulcers significantly worse to the point of being unable to brush my teeth, eat almost anything, and was eating away at my gums and cheeks. Azathioprine has been the solution that has kept the mouth ulcers at bay."
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Azathioprine "Shortly after commencing Imuran at a low dose (50 mg/day), I developed a severe and persistent headache and also felt very tired and listless. One week later, everything got a lot worse: within 24 hours of commencing the higher dosage (100 mg/day), I began to feel extremely nauseous, and about an hour later, non-stop vomiting commenced. I couldn't even swallow a mouthful of water without bringing it up almost immediately. That night, all the joints in my body began to swell up and become very painful. By 3 a.m., I could barely walk, and by 7 a.m., my husband had to call in emergency services: my BP had dropped to 56/40, so I was immediately taken to the hospital, where I was treated with copious amounts of IV fluids, antiemetics, and high doses of corticosteroids. Over the next few days, I very gradually began to improve and was discharged from the hospital 6 days later, but it took many weeks before I was anywhere near back to normal."