Skip to Content

User Reviews for Hydroxychloroquine

Also known as: Plaquenil, Quineprox

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Hydroxychloroquine.

Filter by:
Condition DownUp Reviews Compare Avg. Ratings DownUp
Lyme Disease, Arthritis 4 reviews 35 medications
   
9.7
Dermatomyositis 4 reviews 15 medications
   
9.0
Systemic Lupus Erythematosus 35 reviews 97 medications
   
8.1
Sjogren's Syndrome 28 reviews 6 medications
   
7.6
Rheumatoid Arthritis 64 reviews 341 medications
   
6.7
Undifferentiated Con...e Tissue Disease 15 reviews 2 medications
   
6.4
Summary of Hydroxychloroquine reviews 150 reviews 7.9

Reviews for Hydroxychloroquine

Sort by:

Plaquenil (hydroxychloroquine) for Systemic Lupus Erythematosus: "I was eventually diagnosed with SLE in 2012, 3 months after my first (& worst) flare. I took prednisone for a week, & started taking 200mg plaquenil & 2400mg ibuprofen daily, & 50-150mg tramadol as needed for pain. In my experience, the prednisone helped to reduce the excruciating, debilitating joint pain by calming the inflammation, & plaqenil & ibuprofen keep it at bay...for the most part. My rheumatologist took me off plaquenil 2 years ago; I still take 400 mg of ibuprofen 2X/week. I still get flares once or twice a year, but they are not as bad...6, as opposed to a 10 , on the pain scale. Tinnitus started a few weeks after I started plaquenil & I still have it. It's vastly annoying, but at least it doesn't hurt! best of luck to all!"

   
7.0

emily towson (taken for 2 to 5 years) January 7, 2017

0 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "A wonder-drug to me when I first took it. Almost all the pain in hand joints stopped within a week - after 10-15 years of continuous pain which I had just ignored, but couldn't now face going back to. I'm still almost entirely pain-free in the joints - just a shadow of it in the evening when I'm tired. I do have side-effects though. Terrible constipation and trapped wind, getting worse at present and making me feel sore inside. Also headaches and irritability in the evening, though these are worth putting up with for the increased clarity of thought in the daytime. The 'horrible' feeling someone talked of - I had just a week of it. Like another body, full of pain, just behind the new one. alternating like an alternating current..."

   
7.0

alyth (taken for 1 to 6 months) January 5, 2017

0 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Undifferentiated Connective Tissue Disease: "I am 54 years old and female. I have taken Plaquenil only 10 days. Immediately on taking it my joints have felt like they have a burning sensation. I am tired and I ache more than I ever have. I am depressed and don't want to go anywhere because I hurt. The reason I went to the doctor was because I have tendinitis in more than one place, ankles, hip, knee and wrist. I felt better without this medicine. I have been reading it takes a few months to let it kick in. I have been in really good shape but since I started this I just lay around and hurt and feel depressed. I am afraid of eye damage and hair loss. I have had the potential for glaucoma for 15 years now because of my high eye pressure."

   
2.0

One who aches December 18, 2016

0 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Plaquenil (hydroxychloroquine) for Undifferentiated Connective Tissue Disease: "I took this for undiagnosed non specific mixed connective tissue myalgia type issues and it made the roof of my mouth and teeth ache. I stopped and the ache went away. I restarted and the ache came back after a couple of days. Went like this back and forth and it was definitely the medicine. Also I started to feel worse while taking it. It could be that the weather is getting colder and that always makes me feel worse. but we decided I couldn't tolerate an increase in dosage which was what would have been next on the treatment plan so we moved on to something else. Still searching."

   
3.0

Baco77 (taken for 1 to 6 months) December 11, 2016

0 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Undifferentiated Connective Tissue Disease: "Plaquenil changed my life. 90% improvement after about a month of 400mg daily. Without this med, I only function at 10% with several flares per year. With this med, I'm lucky enough to now have 0-1 flares per year. Thank you, rheumy, for saving my life. Side effects are all GI related for the first few weeks to a month, but are no longer a problem after your body adjusts to the med. I also grew my hair back quickly & fully within a year of starting Plaquenil. It is FANTASTIC for fatigue & pain. I am sick much less often than prior to starting Plaquenil (hydroxychloroquine is the generic name.)"

   
10

Cursed-80 (taken for 2 to 5 years) November 30, 2016

2 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Systemic Lupus Erythematosus: "Plaquenil changed my life. 90% improvement after about a month of 400mg daily. Without this med, I only function at 10% with several flares per year. With this med, I'm lucky enough to now have 0-1 flares per year. Thank you, rheumy, for saving my life. Side effects are all GI related for the first few weeks to a month, but are no longer a problem after your body adjusts to the med. I also grew my hair back quickly & fully within a year of starting Plaquenil. It is FANTASTIC for fatigue & pain. I am sick much less often than prior to starting Plaquenil (hydroxychloroquine is the generic name.)"

   
10

Cursed-80 (taken for 2 to 5 years) November 30, 2016

3 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "The first time I took Hydroxychloroquine is last year in March. I was swelling and after taking the drug 200 mg for a few days, my swelling subsided and I was feeling normal again. I found it best to take after lunch but had to take it everyday. I did try to skip a day or two a few months after that but I can see and feel the swelling come back. After that, I try not to skip taking the drug. I was only able to stop taking this medication last August of this year, when I was determined to be happy and accomplish in what I wanted to learn. I accomplished that and went on without the drug until end of October (2 months). I gave up hope learning that topic and feel RA coming back now. I will try not to give up that topic so can stop taking drug"

   
8.0

Khev (taken for 6 months to 1 year) November 3, 2016

6 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Sjogren's Syndrome: "I have sjogrens and subcutaneous lupus, i took this drug 10 years ago no side effects but really no effect, i tried it again 10 years later huge difference and not in a good way, severe nausea and dry heaves, no energy could stay in bed all day, complete weakness , now that I've gone off of it 4 days ago still extreme nausea , I've lost 35 pounds, and was told by pharmacist 2 months to no longer be nauseated. The other immune drugs have scary side effects almost worth waiting for a flare and dealing with steroids then the side effects of the immune suppressants and plaquinel name brand and generic not worth the constant feeling of vomiting there has to be something that works without major life threatening side effects."

   
1.0

Lala lana (taken for 1 to 2 years) October 25, 2016

8 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "I have Sjogren's and RA, put on Hydroxy 400mg a day. I been on them for 3 months and don't notice any difference at all. I do have intense Tinnitus which is now getting almost unbearable. At first I had stomach pains but Omeprazole helps this and also I now have terrible constipation. I don't rate this drug very well at all and am coming off it and will try natural methods to help my symptoms."

   
2.0

Scyl October 1, 2016

6 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "Better than the biologics or methotrexate that caused my lungs to burn up. However, after 7 years of 200 mg b.i.d. I think the time has come to quit this too, I have been experiencing nausea and liver pain for the last few weeks and just recently vomiting and hives followed by four hours of dry heaves. My liver (under and just beneath my right rib cage feels painful and swollen). The biologics are nasty too and my internist said 10 years is max on them as they are know to cause kidney/liver failure in his experience (42 years as an internist). I am not sure where to go from here. This is an awful disease. Diagnosed at 48. Only thing I know to keep the pain at bay is get up and move and don't stop until it's time for bed."

   
6.0

LisaStuDais September 19, 2016

11 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "I was diagnosed with JRA at the age of 2, lead a completely normal life until about 2+ years ago, went to see an RA doctor and she put me on plaquenil about 18 months ago. At first it was a amazing, zero side effects and everything was great. For the past 3 months my symptoms have gone worse. In fact I am having pain that I have never had before including joint popping and feeling as though my hip is going to give out sometimes when I walk. I see my doctor next week so hoping for something new. I have never taken any RA meds at all until now and now I feel like I am 90 years old and I am old 48. Exhausted and tired of being in pain."

   
7.0

LaraP September 15, 2016

11 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Plaquenil (hydroxychloroquine) for Sjogren's Syndrome: "I have been on Plaquenil for several years , first the generic Plaqenil has no coating to protect your stomach lining. If you have side affects first try brand . I know Dr. s Say there is no difference ."But" composition of the drug may not affect the effectiveness of drug but it will affect the way it is absorbed in your system. Which will affect your side affects."

   
2.0

Babycakes1949 (taken for 5 to 10 years) September 9, 2016

14 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Plaquenil (hydroxychloroquine) for Rheumatoid Arthritis: "I've been on this drug since 2003. Before meds, I was so sick with RA symptoms. Spent 19 hours a day in bed, couldn't dress or bath myself. Seldom ate. Doctor put me on 200 mg. plaquenil twice daily and 10 mg. prednisone and I got my life back. I've since drop prednisone and am down to 200 mg. once daily plaquenil. About to go on the generic form of plaquenil. A little concerned. Is the quality the same? My specialist said no. RA drugs are so scary. I've had friends die on biologics--and some go blind. My advice as geezergirl. When you find out what works for you, hold on tight to it."

   
10

geezergirl September 5, 2016

33 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Systemic Lupus Erythematosus: "I had been on Plaquenil for nearly 30 years for lupus. So long that I didn't remember any side effects. I saw my rheumatologist recently and he said that he felt that I was in remission so I decided to come off of it for awhile. Within a week or so I noticed that I had a new dimple in my cheek, then within the next week the shape of my face changed and the "apple" cheeks that I had assumed for all these years was from lupus, disappeared. I have lost about 10 lbs since I went off a month ago and no longer have ringing in my ears or crippling vertigo. I do have a lot more pain and swelling but I will never go back on this drug. I am so thankful that I chose to try to go without it."

   
8.0

Beeline (taken for 10 years or more) August 27, 2016

11 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "Plaquenil was the first RA medication I was put on. It did not go well. I was on it for a total of 3.5 weeks, and during that time I have never been so sick in my life. The nausea got worse the longer I was on it. I developed severe vomiting at about two weeks on it. I was debilitatingly exhausted all the time. I lost over 10 pounds in the this short time because I couldn't eat and was getting so violently ill. It also gave me a horrible headache that lasted from day 1 until my rheumatologist discontinued it. After I stopped taking it, the side effects cleared up in about a week. Now that I am off it, I CAN tell it was helping the RA pain and swelling however the side effects were just too much for me."

   
4.0

GCav (taken for less than 1 month) August 23, 2016

13 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Undifferentiated Connective Tissue Disease: "Not sure what I have. High Anti-ccps. Started with left hand finger & joint swelling that did not go away with some joint knuckle pain. Then having some knee and ankle joint pain in mornings that would go away by afternoon. Stiff neck below the skull area to neck spinal area.I would get occasional calf and foot spasms. Muscle weakness and strength gone. Once I started the durg I felt like drug was doing nothing but giving me undesirable side effects. The nausea lessened with time along with the feeling of loss of balance. I felt like my brain was in a fog for quite a while & my energy level is lower with some fatigue about 1/2 hour after taking drug and always with food. These side affects became more tolerable. 17 weeks before improvements"

   
8.0

Kiki100 August 16, 2016

5 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "I was diagnosed with RA when I was 30 years old. I'm 37 now. My rheumatologist started me out on Methotrexate which put me in the hospital for sever flu like symptoms for an extended period of time. I have just started Hydroxychloroquine, I am on 200mg once a day and have noticed it leaves me feeling out of sorts, and I often have headaches along with nausea despite taking it with meals. It has caused me to miss work on several occasions. I'm hoping that with time some of the side effects will subside and I'll be able to enjoy a better quality of life."

   
4.0

Chorty79 August 5, 2016

6 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Plaquenil (hydroxychloroquine) for Rheumatoid Arthritis: "I started on Plaquenil for RA about two months ago so my experiences are fresh. I'm a large male at 6'2 250 pnd 30 years old. When I was diagnosed with RA I didn't know what to expect. I was quickly referred to a Rheumatologist who recommended this drug. The first three weeks I was having some side effects. Nose bleeds, ringing in my ears. But after the fourth week they just disappeared. As well as the excruciating pain in my feet, knee's and hands. It just poof like it never happened. I'm optimistic about now my third month as it has now been three months since my last flare up. It was too late for my feet, which now have permanent damage, but I can now walk and wear shoes almost perfectly normally."

   
9.0

Enz (taken for 1 to 6 months) July 25, 2016

40 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Plaquenil (hydroxychloroquine) for Undifferentiated Connective Tissue Disease: "I did not have any adverse effects as such on starting this medication except mild skin rash, have been on it for about 4 years. Have been relatively okay but what produced a dramatic improvement was an antiinflammatory , antitoxic diet with no artificial,packaged or canned foods, no sodas etc. accompanied by yoga and especially breathing exercises pranayama dIly 30-45 minutes which produce miraculous results over time."

CharlotteA1979 (taken for 2 to 5 years) July 20, 2016

11 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Plaquenil (hydroxychloroquine) for Rheumatoid Arthritis: "I have been taking plaquenil for about 4 years 200 mg twice a day . I have been having severe stomach cramps and nausea and vomiting just now realized it's the plaquenil. Because I didn't take it for 3 days because of the n/v just took it again today and got so sick had to throw up. Now realized it's the plaquenil have been to gastro dr and have done all kind of test .will not be taking this med again my Ra is nothing as bad as n/v maybe this will help some one . Don't no what I will take for this Ra pain I feel so sorry for anyone who has this Ra was not diagnosed with this untill I was 65 years old."

Anonymous June 25, 2016

32 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "Tried Methotrexate twice and both times it caused Chronic Ulcerative Colitis so my consultant put me on Hydoxychloroquine. Started on 2 tablets a day but after 3 weeks I cut it down to 1 as it was upsetting my stomach. It halved my inflamation in about 5 weeks! BUT! After taking it for 3 months I began to get very constipated and after 4 months I had blood when I passed a stool so I stopped taking it, as I thought my UC was coming back. Now 6 weeks later I am suffering with chronic indigestion and have to drink several sachets of Macrogol per day to be able to go to the toilet. My doctor's not given me any indication as to how long this will last or if my stomach's been permanently damaged so I am going to make an appointment to find out!"

   
3.0

Nannysoo (taken for 1 to 6 months) June 25, 2016

12 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "I have been taking 200 mg of Plaquenil 2x/day for about 8 weeks. I notice stomach discomfort even though I take it with a meal. The one side effect I don't see mentioned anywhere is that it lowers my iNR and I've had to increase my warfarin dosage. I do see a great change in the amount of pain in my joints!! I actually have days that I feel good again!! Praise God!"

   
8.0

LindD June 22, 2016

15 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Rheumatoid Arthritis: "My RA Dr. Prescribed 200mg 2X P/Day - Approximately 1 month ago. I feel a great difference on improvement of pain relief! But, I do have to eat prior to taking or I get nauseous. Also, I get very sweaty - dripping sweaty, It's terrible! But the RA Pain is So Much Worse than being sweaty & nauseous, so I will continue to take this medicine! Aside from the 2 side effects I mentioned Plaqunil has relieved my pain substantially!"

   
8.0

Bans May 14, 2016

17 users found this comment helpful. Did you?   Yes   No Report as inappropriate

For Systemic Lupus Erythematosus: "I was diagnosed with Sjogrens and systemic lupus some 5 years ago after 3 years of tests etc. Initially was on 40mg plaquenil and 30 mg predisinole(steroids). After 2 year was weaned of the steroids, I gained so much weight and the moon face was terrible. Have had several flare ups when I take 10-15mg steroids for a couple of days. Plaquenil has helped me a lot, initially I had a job to get out of bed, so tired, every joint and muscle ached and hurt, but this has reduced over time, I still get terrible pains in my joints, suffer severe reaction if i don't use 50 sunscreeen all the time, but my quality of life has increased 65%, I am now on reduced plaquenil of 200mg per day, steroids as and when I get a flare up."

   
8.0

jude the prude April 25, 2016

12 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Plaquenil (hydroxychloroquine) for Undifferentiated Connective Tissue Disease: "I was on this medication for one day when I began to gave sereve vomiting 30 minutes after taking it and stomach bloating and uncontrollable gas. By day six I called my doctor to tell him I had bilateral muscle weakness in my legs and could hardly walk a straight line without feeling like I was going to fall down. My doctor stopped the medication after six days after I began to take it when I presented with a known severe adverse side effect of this medication " muscle weakness and loss of coordination""

   
1.0

Anonymous March 15, 2016

19 users found this comment helpful. Did you?   Yes   No Report as inappropriate
Page 1 2 3 4 5 6 Next
Hide