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User Reviews for Plaquenil

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Lyme Disease, Arthritis
9.7
   
3 reviews 35 medications
Dermatomyositis
9.0
   
3 reviews 15 medications
Systemic Lupus Erythematosus
8.1
   
22 reviews 97 medications
Sjogren's Syndrome
7.3
   
19 reviews 5 medications
Rheumatoid Arthritis
6.7
   
46 reviews 349 medications
Undifferentiated Con...e Tissue Disease
4.7
   
10 reviews 2 medications
Summary of Plaquenil reviews 7.1 103 reviews

Reviews for Plaquenil

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For Rheumatoid Arthritis "I tried this med for mild to moderate rhuematoid arthritis and after a few days of stomach aches I started getting severe stomach pain that had me doubled over. I realized it had begun when I started taking the Plaquenil. I called my dr and we agreed I should not be taking it. Less than 24 hours later my pain was gone. Not for me! Never again... it was a terrible experience!"

   
1.0

kat (taken for less than 1 month) October 1, 2018

1 users found this comment helpful.
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For Sjogren's Syndrome "Did not help me. It gave me nightmares."

Godfrey (taken for 10 years or more) September 1, 2018

0 users found this comment helpful.
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"I have been on plaquenil for two years for psoriatic arthritis. I have severe sacroiliac disease and wrist and fingers involved. It has been miraculous. Maybe I am a rare guy but it worked within days. Whenever I came off it travelling to a sunny destination or to try only an anti inflammatory for a flare or even a steroid injection things were bad until I restarted plaquenil. Then it was like a switch boom. Better. Each day ten per cent better. I read there are anti inflammatory properties. I must have lucked out. This is too good an improvement to put it on placebo effect. Plus that's not me - I am a sceptical family doctor !!! Definitely worth a first try before methotrexate or biologics."

   
10

Gattisdoc August 17, 2018

1 users found this comment helpful.
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For Rheumatoid Arthritis "It is working for me."

   
9.0

Anonymous (taken for 1 to 6 months) August 13, 2018

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For Rheumatoid Arthritis "I started on plaquenil for Psoriatic Arthritis in 2015. (200mg twice daily). I didn’t feel too bad but a huge bout of stress made my symptoms worse. I then started methotrexate in addition to plaquenil. My rheumatologist suggested once daily Plaquenil and that seemed okay. After a while he said I coujd stop it as he was not sure if it was working. I tapered off the dose and I slowly began feeling dreadful. The fatigue was awful and I had weird signs akin to severe fibro. I then started back on twice daily plaquenil. Within two weeks I began to feel more human and six months later the fatigue is greatly improved. The small joints in my hand and my wrists are less sore: still painful but improved. I can do more now and feel like doing more. I still have some bad fatigue days and the rheumatologist is still talking about biologicals but for the moment I’m happy to see how I go. None of these drugs are perfect but at this stage plaquenil is really helping me."

   
9.0

Amber2 (taken for 2 to 5 years) March 23, 2018

8 users found this comment helpful.
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For Rheumatoid Arthritis "Well I posted once before, figured I would give another update for anyone who cares. It's been around 2 years now and I'm glad to say all side effects are long gone. So is my pain for the most part. Sometimes I forget I was even diagnosed with RA (Palindromic Rheumatism). Every once in awhile I will have a flare, my last one was in October of last year 2017, it is now Feb 2018 and still flare free. I've been seeing gaps of 6+ months without any pain. You can see why it's easy to forget lol. Again, this drug is worth it. It seems almost like a dream waking up and not being able to move, a horrible dream."

   
10

Enz (taken for 2 to 5 years) February 15, 2018

16 users found this comment helpful.
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For Rheumatoid Arthritis "I've been using Plaquenil 3 months. It has helped my RA pain subside a lot. While my Rheumatologist says I'm in the beginning stages of RA, she nonetheless put me on the Plaquenil. However, my hair is falling out rapidly so I have weened myself off of it and will never use it again."

   
9.0

Diane Schumacher (taken for 1 to 6 months) February 13, 2018

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For Undifferentiated Connective Tissue Disease "I've been on and off Plaquenil for 13 years for Undifferentiated connective tissue disease (UCTD). I have NEVER had a flare while on plaq. The only times I've had flares was when I stupidly stopped taking plaq. That is a mistake I will never make again, after a life threatening flare in 2015. Now I am on plaquenil for life, and 100 % in remission. This drug has been absolutely amazing for me. I guess it just depends on individual body chemistry, but I love this drug so very, very much. Now, honestly, you have to give it 3-6 months to fully take effect, and it can cause GI upset and other side effects at first. You just have to tough it out and be strong-minded. Plaq is a game changer for many UCTD patients but you need to be tough and patient!! Don't skip doses."

   
10

LGFr (taken for 10 years or more) December 24, 2017

7 users found this comment helpful.
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For Rheumatoid Arthritis "I have been on Plaquenil for about 15 years without apparent side effects until this year. But this year I have developed severe swelling of the face and red rash on the upper half of my face. This also includes very difficult itching in odd places on my body, my eyebrows and eyelashes, my earlobes, my lower legs and lower arms, my scalp and of course where the red rash was. This was twice cleared up with heavy doses of antibiotics and Cortisone. However my rheumatologist took me off all arthritis drugs and we added them back little by little. When plaquenil was finally included with the other drugs again, it took about three days and my My face started swelling and the rash and and itching. I can only assume that this was the cause of my allergic reaction, even after all the years of use."

   
7.0

C Wife December 9, 2017

9 users found this comment helpful.
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For Rheumatoid Arthritis "I am a 72 year old female, diagnosed with RA 6 years ago. I took Plaquenil (200x2) from 2012-2016, along with Prednisone to start. Due to the fact, I could not use my hands because of the swelling, I risked the possible vision problems. By 2012, symptom free and still fearful of vision loss, I stopped the drug. I was pain and symptom free for one year, but now symptoms have returned, and I have been told to restart the drug(no prednisone.) In the 4 years taking it, I went from 95 lbs. to 85 lbs., lost a significant amount of hair, had cataract surgery and, now, macular degeneration. The decision to restart is extremely emotionally stressful, weighing the benefits against the risk. (Dr. says neither eye problem was caused by the drug"

   
10

Backside of 70 November 4, 2017

14 users found this comment helpful.
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For Rheumatoid Arthritis "I primarily treat my RA with CBD paste. While it does pretty good alone, my doctor suggested that Plaquenil might zero out the rest of my symptoms. Even though I have a fairly severe case of RA, the CBD Paste manages about 80% of the disease. But I've been taking the Plaquenil about 3 weeks, and honestly, I think I have more swelling. I've decided to stop for now and am wondering if Plaquenil can actually make the symptoms worse?"

   
4.0

RA treatment October 6, 2017

20 users found this comment helpful.
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For Systemic Lupus Erythematosus "I've been taking this medicine for 4 days. I have not experienced any negative side effects yet. No nausea or jittery feelings like others I've read about. Since starting this medicine I've noticed I've slept like a rock. No waking up at all and no problems falling asleep. I just felt I should share this observation since I was terrified to start after reading all these horror stories. Not everyone is negatively affected."

   
10

ShellyBeans333 (taken for less than 1 month) September 3, 2017

24 users found this comment helpful.
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For Rheumatoid Arthritis "I am still trying to figure out what this drug is suppose to do cause I still get the soreness in the joints and the swelling especially in the shoulders and hands some nites its hard to sleep unless I take something for the pain in both"

spunkies (taken for 1 to 6 months) August 27, 2017

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For Systemic Lupus Erythematosus "I'm in Australia , only just started this medication a week ago but I feel a less fatigued already. I was stuck in bed most days, but now I can go longer without needing to go to bed or feeling like I'm going to collapse. I haven't noticed any bad side effects yet either which is good! As I get nauseated and dizzy on meds easily and haven't found that to be the case! I just wanted to point out that some people hear a lot of bad things that aren't necessarily reported or true. Like I noticed a woman on here said she needs to stop taking it because of the tinnitus side effect means she might go deaf. But deafness hasn't been reported, just tinnitus as a side effect whilst taking it. Don't be so afraid if it's going to give u your life back"

   
8.0

Cass888 (taken for less than 1 month) August 27, 2017

13 users found this comment helpful.
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For Undifferentiated Connective Tissue Disease "I took this medication for only 3 weeks for Mixed Connective Tissue Disease. (Diagnosed 15 years ago, medication free for the last 11years). My only active symptom at the time was Raynaud's. I really did not want to take any medication, and felt that improving my lifestyle/keeping warm was worth a try, but my (new) rheumatologist pushed it and said he would discharge me if I didn't take it. All my other tests (lung function, heart scan, bloods) were fine. What a mistake. It did not help my Raynaud's, but did cause huge hives from my neck to my ankle. My last dose was May 25th, it is now August 9th and these unsightly hives continue to come and go. With such a long half life (up to 50 days) it will take over 18 months to fully eliminate it"

   
1.0

LucyDJ (taken for less than 1 month) August 9, 2017

10 users found this comment helpful.
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For Rheumatoid Arthritis "Haven't taken this. Just wanted to read some feedback. I was on methotrexate, but stopped, because it gave me chills, fatigue and shortness of breath, I even fainted at work. The doctor suggested Plaquenil as a possible alternative, but after reading some of the comments, I don't think so. This is really frustrating and sad. The FDA should NOT be approving these crappy drugs which can cause worse problems than the one you have. I honestly don't know what to do, let the RA turn me into a cripple or take my chances with one of these death drugs?"

Darkchief99 June 6, 2017

42 users found this comment helpful.
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For Rheumatoid Arthritis "Love this drug, compared to the others. I am 55 now, and first took it 30 years ago. My RA then came on lightening fast, nodules and all. I went from totally normal to almost wheel chair in weeks. The weight of a bed sheet on my toes was too much. Two plaquenil a day and 2400 mg of ibuprofen a day ( that's 12 regular dose!) and I went into total remission. Of course my stomach is crap now. After 25 years of remission, the RA returned. Different now that I'm older (55), more subtle. Chose plaquenil again, and working wonders, but for my permanent damage. Get your eyes checked, a must. Some hair will fall out, but hey, I'm glad I still have some to fall out. WEIRD dreams. Irritability. Will lose weight! TAKE WITH FOOD to avoid cramps."

RichEsq April 13, 2017

70 users found this comment helpful.
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For Rheumatoid Arthritis "I've been on Plaquenil for over 3 months now. It works wonderfully! I combine my treatment with Curcumin & Magnesium baths and I feel like a new woman :-) Side effects I experienced: Nausea & dizziness for the first week or two (I found I needed to take it after a full meal to prevent the nausea). I have also noticed since starting the Plaquenil I seem to sweat profusely. It's annoying, but the benefits far outweigh this little problem. I just wear my gym gear about now... which I did mostly beforehand anyhow :-) Also, it take take a couple months for the Plaquenil to kick in & for me to feel the effects! Don't give up, just give it some time."

   
7.0

KittensAussiePrincess March 26, 2017

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For Rheumatoid Arthritis "I began taking Plaquenil for RA 1 month ago. Despite information from my doctor that it would be at least 3 months before I see an appreciable effect, I am feeling better than I have in the last year. Prior to Plaquenil, I tried Mobic & Medrol, both with limited improvement. But over the last few weeks I have been able to play basketball with my son again, move without thinking or a 'warm up period', return to the gym, begin Pilates & I've lost 12 pounds! I did have some GI upset over the last month, but nothing I would consider stopping this medication for. I am able to enjoy things again & live life without discomfort."

   
9.0

Kat019 (taken for 1 to 6 months) March 3, 2017

81 users found this comment helpful.
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For Sjogren's Syndrome "This was not the answer for me, I developed a bad rash and itching over my entire body and now my ears ring and that will never go away. Just from taking it for under a month."

   
1.0

Stacey333 February 10, 2017

25 users found this comment helpful.
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For Systemic Lupus Erythematosus "I was eventually diagnosed with SLE in 2012, 3 months after my first (& worst) flare. I took prednisone for a week, & started taking 200mg plaquenil & 2400mg ibuprofen daily, & 50-150mg tramadol as needed for pain. In my experience, the prednisone helped to reduce the excruciating, debilitating joint pain by calming the inflammation, & plaqenil & ibuprofen keep it at bay...for the most part. My rheumatologist took me off plaquenil 2 years ago; I still take 400 mg of ibuprofen 2X/week. I still get flares once or twice a year, but they are not as bad...6, as opposed to a 10 , on the pain scale. Tinnitus started a few weeks after I started plaquenil & I still have it. It's vastly annoying, but at least it doesn't hurt! best of luck to all!"

   
7.0

emily towson (taken for 2 to 5 years) January 7, 2017

20 users found this comment helpful.
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For Undifferentiated Connective Tissue Disease "I took this for undiagnosed non specific mixed connective tissue myalgia type issues and it made the roof of my mouth and teeth ache. I stopped and the ache went away. I restarted and the ache came back after a couple of days. Went like this back and forth and it was definitely the medicine. Also I started to feel worse while taking it. It could be that the weather is getting colder and that always makes me feel worse. but we decided I couldn't tolerate an increase in dosage which was what would have been next on the treatment plan so we moved on to something else. Still searching."

   
3.0

Baco77 (taken for 1 to 6 months) December 11, 2016

6 users found this comment helpful.
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For Sjogren's Syndrome "I have been on Plaquenil for several years , first the generic Plaqenil has no coating to protect your stomach lining. If you have side affects first try brand . I know Dr. s Say there is no difference ."But" composition of the drug may not affect the effectiveness of drug but it will affect the way it is absorbed in your system. Which will affect your side affects."

   
2.0

Babycakes1949 (taken for 5 to 10 years) September 9, 2016

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For Rheumatoid Arthritis "I've been on this drug since 2003. Before meds, I was so sick with RA symptoms. Spent 19 hours a day in bed, couldn't dress or bath myself. Seldom ate. Doctor put me on 200 mg. plaquenil twice daily and 10 mg. prednisone and I got my life back. I've since drop prednisone and am down to 200 mg. once daily plaquenil. About to go on the generic form of plaquenil. A little concerned. Is the quality the same? My specialist said no. RA drugs are so scary. I've had friends die on biologics--and some go blind. My advice as geezergirl. When you find out what works for you, hold on tight to it."

   
10

geezergirl September 5, 2016

93 users found this comment helpful.
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For Rheumatoid Arthritis "I started on Plaquenil for RA about two months ago so my experiences are fresh. I'm a large male at 6'2 250 pnd 30 years old. When I was diagnosed with RA I didn't know what to expect. I was quickly referred to a Rheumatologist who recommended this drug. The first three weeks I was having some side effects. Nose bleeds, ringing in my ears. But after the fourth week they just disappeared. As well as the excruciating pain in my feet, knee's and hands. It just poof like it never happened. I'm optimistic about now my third month as it has now been three months since my last flare up. It was too late for my feet, which now have permanent damage, but I can now walk and wear shoes almost perfectly normally."

   
9.0

Enz (taken for 1 to 6 months) July 25, 2016

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