Skip to main content

User Reviews for Rituximab

Also known as: Rituxan, Ruxience, Truxima, Riabni

Rituximab has an average rating of 7.6 out of 10 from a total of 112 ratings on Drugs.com. 69% of reviewers reported a positive experience, while 15% reported a negative experience.

Condition Avg. Rating Reviews Compare
Rheumatoid Arthritis  
7.4
77 reviews 363 medications
Non-Hodgkin's Lymphoma  
8.5
15 reviews 36 medications
Chronic Lymphocytic Leukemia  
9.4
6 reviews 23 medications
Granulomatosis with Polyangiitis  
9.5
4 reviews 5 medications
Focal Segmental Glomerulosclerosis  Off-label
6.7
3 reviews 3 medications
Bullous Pemphigoid  Off-label
5.0
2 reviews 77 medications
Idiopathic Thrombocytopenic Purpura  Off-label
7.5
2 reviews 75 medications
Microscopic Polyangiitis  
6.0
2 reviews 5 medications
Follicular Lymphoma  
7.0
1 reviews 13 medications
Summary of Rituximab reviews 7.6 112 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Rituximab

peggy6537 · March 6, 2009

Rituxan (rituximab) for Rheumatoid Arthritis: “I have had 2 infusions of Rituxan for rheumatoid arthritis. Within 4 days of the first infusion I was beginning to feel better. I am 5 days out from my second infusion and I can already move with little or no pain for the first time in over a year. For me, its been a life saver.”

9 / 10
Was this helpful?YesNo
MsAnna · Taken for 2 to 5 years · June 30, 2017

Rituxan (rituximab) for Rheumatoid Arthritis: “After failing all other RA treatments, I was high-dose steroid dependent and running out of options. I'll admit, the PML risk had scared me off from trying Rituxan sooner; however the increasing (and very real) risk of becoming non-functional scared me more. I began infusions about 4 years ago. While most patients receive concomitant methotrexate therapy, I do not, due to liver damage from previous methotrexate use. Rituxan has improved my quality of life physically, mentally, emotionally. My advanced RA will never allow me to live "normally" but I am the best me I can be with this treatment. Side effects are minimal for me; nausea for a few days after each infusion. That's my story!”

9 / 10
Was this helpful?YesNo
Nosymptoms · Taken for 1 to 2 years · September 27, 2015

Rituxan (rituximab) for Rheumatoid Arthritis: “Rituxan has completely changed my life for the better. I was in a clinical trial and tried several other medications with some success but my symptoms eventually returned. After four sessions of Rituxan over a two year period I stopped seeing my RA doctor because I had no symptoms. I am now going into my 4th year without pain. I am playing softball, tennis and golf without any pain. I highly recommend this drug to anyone dealing with RA.”

10 / 10
Was this helpful?YesNo
Anonymous · Taken for 6 months to 1 year · April 13, 2013

For Rheumatoid Arthritis: “This is a follow up to a review I left on 18th July '12. It took 4 months for rituximab to start making a real difference and what a difference it has made to me. I can now walk and do most things that I couldn't do before I got it. I had another infusion yesterday and I will get another in 2 weeks and that will complete my 2nd course of it. That was 10 months between infusions although you can get it again after 6 months. I had Enbrel before starting rituximab but it didn't do a thing for me, in fact I think I got worse but rituximab has been fantastic. The infusion took around 6 hours but it was painless and I had no problems at all during it, although I would recommend taking a book to read as it is quite a long time sitting.”

9 / 10
Was this helpful?YesNo
myra · Taken for less than 1 month · January 4, 2019

Rituxan (rituximab) for Rheumatoid Arthritis: “In mid December of 2018 I had my first infusion after others like orencia no longer worked. I was scared of this drug because of the noted side effects. I had no pain in my joints after my first infusion. A day later I had a lot of energy and did not get tired like before. I went 2 weeks later for the second infusion & continue to feel no pain. No side effects so far. Finally got off steroids. I did feel very tired last night, a first. Perhaps it was because I was really tired. Woke up this morning feeling well rested and no pain. I hope this is a sign of things to come.”

10 / 10
Was this helpful?YesNo
Buffytulsa · December 15, 2014

For Rheumatoid Arthritis: “I have been in Rituxan for 10 years. Almost wheel chair bound at 35. I prayed it would work. And it had put me in remission. It saved my life! I will be on this for the rest of my life if possible. I pray insurance will keep paying.”

10 / 10
Was this helpful?YesNo
Nicoco · Taken for less than 1 month · February 7, 2017

Rituxan (rituximab) for Rheumatoid Arthritis: “This is the first day I've had ZERO pain in 6 years. I tried Enbrel - good but not strong enough after 2 years. Humira - allergic. I just finished my second infusion from Rituxan. And I am cautiously happy. Absolutely no pain anywhere.”

10 / 10
Was this helpful?YesNo

Frequently asked questions

RobGee · June 15, 2014

Rituxan (rituximab) for Rheumatoid Arthritis: “Entering the 7th hour of the process during my 1st infusion; I experienced annoying itching deep within my ears, back of throat, head and face. Shortly after the "push", increasing the drip, I broke out into hives on my face, head and neck with red welts ironically appearing in the areas where I had historically given myself the Enbrel injections...front of both thighs and stomach. Enbrel had stopped its effectiveness after almost 2 yrs and it had been almost 1 month from my last injection prior to the infusion. My Dr made the decision to discontinue the infusion fearing that my allergic reaction may cause anaphylaxis.”

1 / 10
Was this helpful?YesNo
Baby Girl Chris · October 3, 2014

For Rheumatoid Arthritis: “My rheumatoid arthritis was so severe that I have had four joint replacements (both hips and both knees) within 4 years. I have tried Enbrel, Humira, and Remicade and none of them were effective. My joints were stiff and my flares were frequent, I was in so much pain and was very depressed because of my limitations. My Rhuematologist, who I feel is totally the best, told me about Rituxan (rituximab) and I agreed to try it in 2010. After my first infusion, I felt this was miracle pill because I had immediate positive results. I did not have ANY of the side effects that others have spoken about. I know that Rituxan gave me back my quality of life and my infusions can last up to a year. I'm still on it.”

10 / 10
Was this helpful?YesNo
Anonymous · October 3, 2011

Rituxan (rituximab) for Non-Hodgkin's Lymphoma: “After first round of chemo with Rituxan...my lymphoma lump was completely gone to the touch. Yes...I did have a mild reaction the first time Rituxan was administered, but it was easily resolved with a little Benadryl and a slow down of the Rituxan drip. I did not have any allergic reaction of the subsequent two rounds of chemo. After only three rounds of chemo, I had another PET/CT scan...and was deemed in total remission. Almost a year later....and still no return of the lymphoma and I feel great. It is amazing what medical science can do today to treat and cure people of cancer.”

10 / 10
Was this helpful?YesNo
Minagarie · June 4, 2016

For Rheumatoid Arthritis: “Diagnosed with Rheumatoid Arthritis in 1997. Failed Enbrel and Humira with hives, itching. Tried Orencia but their patient program and delivering meds was a huge disappointment (IV med only available at the time). MTX caused my liver enzymes to go nuts. Started Rituxan in 2009. My results were atypical. Rituxan is my liquid gold with a platinum price tag! A few weeks after my 2nd infusion, I felt incredible. I started running and biking. I lost 83 lbs in 4 months. I went from 235lbs of prednisone, sedentary and having 3 kids increased weight to a healthy 152lbs. I wasnt fatigued. For the first time in 19 years I was in remission while not pregnant. Not for everybody, but great for me.”

10 / 10
Was this helpful?YesNo
Linz · Taken for 1 to 2 years · January 20, 2019

For Rheumatoid Arthritis: “My first round of rituximab infusions (in Dec 2017) took 13 weeks to work, then was good for about 8 weeks then wore off. My consultant said it often worked better 2nd time around. So I had the second round of infusions June 2018. This time it worked after about 7 weeks and has continued to work really well - it's now Jan 2019 and I'm still fine... amazing..... my consultant was totally right! I'm due my third round of infusions this week and am no longer in fear of the med not working. It is really good - after 14 years of RA treatments I would say this is my best med. No methotrexate needed. I've not had any side effects - I haven't even caught any more colds than anybody else! If thinking of trying out this med be patient and good luck - it might give you your life back! Incidentally, it also cured my husband's lymphoma when he was given R- Chop (cyclophosphamide, doxorubicin, vincristine, and prednisone plus Rituxan) medication.... so we've a lot to thank the NHS and the scientists who developed this med for! x”

9 / 10
Was this helpful?YesNo
Beck beck · November 14, 2016

Rituxan (rituximab) for Rheumatoid Arthritis: “I had my first round 6 months ago sitting here starting my 2nd round as we speak. No side effects and even though my joints are still swollen I feel so much better. My dr is hopeful that this round will help with the inflammation. I'll get my 2nd dose with this round in 2 weeks!! I'm hopeful and thankful”

8 / 10
Was this helpful?YesNo
Judi in Bon Air, Va. · Taken for 1 to 2 years · July 2, 2013

Rituxan (rituximab) for Chronic Lymphocytic Leukemia: “I was diagnosed with CLL 10/2005. I began Rituxan 5/2012 once the lymph nodes began to enlarge and my counts were doubling. Initially I was infused once per week for a month; I have continued with this infusion but moved to a monthly visit. It is now July/2013 and my numbers have dropped significantly and my doctor has moved to a maintenance program....infusion every other month. I have never had any side effects from the infusions and doctor is pleased that I've not required chemotherapy medicines added to get same results. Prior to each infusion, I take two 25mg Benadryl and a Tylenol. Perhaps these medicines beforehand have aided me. I have no complaints!”

10 / 10
Was this helpful?YesNo
SRR · Taken for 2 to 5 years · June 7, 2018

Rituxan (rituximab) for Rheumatoid Arthritis: “I’m sensitive & allergic to more meds than not. I was diagnosed with RA 10 years ago @ 35 years old. We tried everything, and decided on retuxin, which scared me, but I’m so grateful I tried it! First one was very uncomfortable, I can’t take any steroids (very allergic) so I rely on Benadryl IV. I had a mild reaction toward the end, felt bad for days. Went 2 weeks later, same thing. I thought, I’m not doing this if I’m going to feel rubbish for 2 weeks. Almost exactly 4 months later, I started feeling all the fun stuff that had gone with RA. I had forgotten how I typically felt. It worked very quickly on me, and has only gotten better. I went to my doc, she said, you’re a 4 month person. Personally, retuxin was the starting point of a complete life shift. I felt better, which gave me energy, which allowed me to slowly start going to the gym, which goes hand in hand with eating clean. It has been a life changing medication for me.”

10 / 10
Was this helpful?YesNo
shaunh · January 6, 2012

For Rheumatoid Arthritis: “Having had 2 infusions within 2 weeks of each other twice a year for the last 4 yrs it has to be said that it took a while for it to work, along with methotrexate and prednisolone but once kicked in it has improved my condition lots. You do get a feeling of a cold coming on to begin with but without doubt it has been the best medication by far. Although having tried HJumira it gave me pneumonia, 11 yrs of medicine mixtures rituximab is by far the best.”

9 / 10
Was this helpful?YesNo
BigPoppy · April 16, 2017

Rituxan (rituximab) for Rheumatoid Arthritis: “I had first infusion with no problems during administration but 2 weeks after I had to go to the E.R. with a heart arrhythmia and had to have my heart shocked back into normal rhythm. Two days later had second infusion with no problems during administration. 2 weeks later same thing...back to the E.R....heart shocked back into rhythm . Heart rate was stuck at 150 bpm. Had to be put in hospital for 4 days to be given an anti - arrhythmic drug that can also cause a fatal arrhythmia. So I would be cautious if you have any type of heart problem prior to taking Rituxan. I will not ever take it again.”

3 / 10
Was this helpful?YesNo

More FAQ

Anonymous · October 14, 2011

For Rheumatoid Arthritis: “I was previously on Remicade that put me into remission for a few years. I wanted to have a child so I had to discontinue all medicines. I was still in remission so all was fine until a year ago when my hip just gave out. Needless to say, I am too young for hip surgery so my RA doctor recommended Rituximaub. I had my first does 3 days ago. I had a bad reaction after the rate was increased but after another dose of Benadryl and slowing down the medicines, all was fine. I have had no pain in my hip and feel great besides the grogginess from the Benadryl. My second dose is in 2 weeks and I hope that my pain will be gone (for at least 6 months). To God be the Glory!”

9 / 10
Was this helpful?YesNo
Donna · Taken for 5 to 10 years · December 28, 2019

Rituxan (rituximab) for Rheumatoid Arthritis: “I’ve been on Rituxan infusions two to three times a year for 10 years. My RA symptoms are virtually non-existent. Don’t want to change meds/therapies. Tried Enbrel with methotrexate, remicade with methotrexate. None of the above gave me relief until Rituxan!”

10 / 10
Was this helpful?YesNo
Creaky joints · Taken for 5 to 10 years · May 20, 2016

For Rheumatoid Arthritis: “I am sat having my 10th cycle, 1st infusion of rituximab. Sleepy while having infusions otherwise no side effects. Previously I could not walk or look after myself. I had no quality of life. Now enjoying life with a little help. My rheumatoid hasn't gone completely but is more manageable to deal with. Not pain, or inflammation free but much better than I was. I know the side effects can sound very scary but discuss this with your consultant or specialist nurse. They are very helpful, very informative and understanding. They do not know the long term side effects of this drug but more importantly I can now live a life as before I was just existing. Try not to be daunted, ask, ask, ask and don't be afraid to try new drugs they might help”

8 / 10
Was this helpful?YesNo
marybrnrd · Taken for less than 1 month · December 12, 2014

For Rheumatoid Arthritis: “I had my very first infusion of Rituxan today, I feel like I have tried EVERYTHING. I've had Enbrel, Orencia, Humira, Xeljanz, Methotrexate, Remicade. All thumbs up so far. The infusion experience was great. I feel better but we also pushed Solumedrol steroids so that could be why. Crossing my fingers for no latent side effects and good results. Will try to check back in two weeks after second infusion.”

10 / 10
Was this helpful?YesNo
jmbwholesale · Taken for 5 to 10 years · May 14, 2013

Rituxan (rituximab) for Non-Hodgkin's Lymphoma: “In 2009 after 6 rounds of RCHOP chemo, then BCNU chemo in the hospital, a bone marrow transplant, I had 3 years of remission. In Oct. 2012, rediagnosed out of remission, started on 6 rounds of bendamustine and Rituxan. The 6th month was skipped due to a low WBC of 2.4. I will continue on Rituxan for maintenance. I began my journey at stage 4E. I was rediagnosed after a fall in May, and was back to stage 4 by October 2012, so the combination of bendamustine and Rituxan have done good. I will receive Rituxan every 3 months or sooner as a precautionary measure.”

9 / 10
Was this helpful?YesNo
Duarte · March 30, 2011

Rituxan (rituximab) for Non-Hodgkin's Lymphoma: “Extremely important medicine for me with Lymphoma low grade stage 1 under my right eyelid. Very rare location for lymphoma. The first time I did 4 sessions with Rituxan in Jun/2010 and now March/2011 the second time. The pictures show my eyes before and after and big different this medicine made. Thanks doctors and nurses for brilliant work. Itchy was my first side effect and second time no side effects at all. Highly recommended.”

9 / 10
Was this helpful?YesNo
Dorko · January 25, 2019

For Rheumatoid Arthritis: “I'm not sure what to think of this drug. I had to stop working in Nov 2018 as the disease (which was in my hands and feet) had attacked my left hip and then knee leaving me unable to walk. This is my eighth drug in four years as NOTHING has worked at all and the side effects were a horror show. Do far I have used hydroxychloroquine, sulfasalazine, methotrexate, Arava, Inflectra, Xeljanz, Kevzara. After my first infusion with rituximab on Dec 12 I had three days of pure bliss. I was in remission...or so I thought. I was pain free for the first time in 4 years .The evening of the third day the pain in my left hip started back and got worse daily. After waiting 4 weeks for the second infusion, I had three hours of relief on the second day after treatment. Since then it has been straight downhill with the pain going back into my knee. I know that Rituxan can take a while to work but I am declining daily...and losing hope.”

1 / 10
Was this helpful?YesNo
Bundy girl · September 10, 2016

For Rheumatoid Arthritis: “This is my second infusion and I am feeling quite nauseous and head aching but know this will pass had an extremely bad headache last night but the relief from the pain has been incredible. Have been on Enbrel cimzia sllalazapirin plaquenil arava am still on prednisone and methotrexate as well as Celebrex but the relief I have had since having my first infusion is like a dream come true I had results within the first few days so there is hope out there .... I can walk a lot easier can actually use my hands which was just so painful... My life is back...don't give up”

10 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.