User Reviews for Rituximab to treat Rheumatoid Arthritis
Also known as: Rituxan, Truxima, Ruxience, Riabni
Rituximab has an average rating of 7.4 out of 10 from a total of 68 ratings for the treatment of Rheumatoid Arthritis. 66% of users who reviewed this medication reported a positive effect, while 19% reported a negative effect.
“I really think this is what finished of my Mum in 3 infusions by destroying her pancreas”
“Have only had 2 lots of rituximab, my first infusion was fine but the second one 2 weeks later has left me not being able to sleep. I go to bed and my body is tired and I want to rest but as soon as I lay down with in 10 mins I have to get back up it feel like ma whole body is restless and jittery this goes on for hours. I have tried reading but can't concentrate have got back up for a hot drinks then gone back to bed same thing, have had baths at 4 in morning as that seems to help but not all the time. Just wondering if this had happened to anyone else and how did they cope as I'm at the end of my tether and want to sleep.”
“I have RA and had my first round of Rituxan on 22June and going for second dose 8 July. Felt pretty great for the first few days with little side effects, thankfully, as so far I’ve been allergic to pretty much everything. Tried Actemera, Xeljanz, Methotrexate and prednisone with little to no relief and a lot of allergies. Woke up in a lot of pain today and am glad I found this page. It seems like it will take a while to start working so I’ll continue to hang in there and be hopeful. Good luck to everyone.”
Rituxan (rituximab): “I have had 2 infusions of Rituxan for rheumatoid arthritis. Within 4 days of the first infusion I was beginning to feel better. I am 5 days out from my second infusion and I can already move with little or no pain for the first time in over a year. For me, its been a life saver.”
Rituxan (rituximab): “After failing all other RA treatments, I was high-dose steroid dependent and running out of options. I'll admit, the PML risk had scared me off from trying Rituxan sooner; however the increasing (and very real) risk of becoming non-functional scared me more. I began infusions about 4 years ago. While most patients receive concomitant methotrexate therapy, I do not, due to liver damage from previous methotrexate use. Rituxan has improved my quality of life physically, mentally, emotionally. My advanced RA will never allow me to live "normally" but I am the best me I can be with this treatment. Side effects are minimal for me; nausea for a few days after each infusion. That's my story!”
Rituxan (rituximab): “In mid December of 2018 I had my first infusion after others like orencia no longer worked. I was scared of this drug because of the noted side effects. I had no pain in my joints after my first infusion. A day later I had a lot of energy and did not get tired like before. I went 2 weeks later for the second infusion & continue to feel no pain. No side effects so far. Finally got off steroids. I did feel very tired last night, a first. Perhaps it was because I was really tired. Woke up this morning feeling well rested and no pain. I hope this is a sign of things to come.”
Rituxan (rituximab): “Rituxan has completely changed my life for the better. I was in a clinical trial and tried several other medications with some success but my symptoms eventually returned. After four sessions of Rituxan over a two year period I stopped seeing my RA doctor because I had no symptoms. I am now going into my 4th year without pain. I am playing softball, tennis and golf without any pain. I highly recommend this drug to anyone dealing with RA.”
Frequently asked questions
- What are the new drugs for the treatment of rheumatoid arthritis (RA)?
- How many biosimilars have been approved in the United States?
- What causes infusion reactions to rituximab?
- What is the difference between Truxima and Rituxan?
“This is a follow up to a review I left on 18th July '12. It took 4 months for rituximab to start making a real difference and what a difference it has made to me. I can now walk and do most things that I couldn't do before I got it. I had another infusion yesterday and I will get another in 2 weeks and that will complete my 2nd course of it. That was 10 months between infusions although you can get it again after 6 months. I had Enbrel before starting rituximab but it didn't do a thing for me, in fact I think I got worse but rituximab has been fantastic. The infusion took around 6 hours but it was painless and I had no problems at all during it, although I would recommend taking a book to read as it is quite a long time sitting.”
Rituxan (rituximab): “This is the first day I've had ZERO pain in 6 years. I tried Enbrel - good but not strong enough after 2 years. Humira - allergic. I just finished my second infusion from Rituxan. And I am cautiously happy. Absolutely no pain anywhere.”
“I have been in Rituxan for 10 years. Almost wheel chair bound at 35. I prayed it would work. And it had put me in remission. It saved my life! I will be on this for the rest of my life if possible. I pray insurance will keep paying.”
Rituxan (rituximab): “Entering the 7th hour of the process during my 1st infusion; I experienced annoying itching deep within my ears, back of throat, head and face. Shortly after the "push", increasing the drip, I broke out into hives on my face, head and neck with red welts ironically appearing in the areas where I had historically given myself the Enbrel injections...front of both thighs and stomach. Enbrel had stopped its effectiveness after almost 2 yrs and it had been almost 1 month from my last injection prior to the infusion. My Dr made the decision to discontinue the infusion fearing that my allergic reaction may cause anaphylaxis.”
“My rheumatoid arthritis was so severe that I have had four joint replacements (both hips and both knees) within 4 years. I have tried Enbrel, Humira, and Remicade and none of them were effective. My joints were stiff and my flares were frequent, I was in so much pain and was very depressed because of my limitations. My Rhuematologist, who I feel is totally the best, told me about Rituxan (rituximab) and I agreed to try it in 2010. After my first infusion, I felt this was miracle pill because I had immediate positive results. I did not have ANY of the side effects that others have spoken about. I know that Rituxan gave me back my quality of life and my infusions can last up to a year. I'm still on it.”
“My first round of rituximab infusions (in Dec 2017) took 13 weeks to work, then was good for about 8 weeks then wore off. My consultant said it often worked better 2nd time around. So I had the second round of infusions June 2018. This time it worked after about 7 weeks and has continued to work really well - it's now Jan 2019 and I'm still fine... amazing..... my consultant was totally right! I'm due my third round of infusions this week and am no longer in fear of the med not working. It is really good - after 14 years of RA treatments I would say this is my best med. No methotrexate needed. I've not had any side effects - I haven't even caught any more colds than anybody else! If thinking of trying out this med be patient and good luck - it might give you your life back! Incidentally, it also cured my husband's lymphoma when he was given R- Chop (cyclophosphamide, doxorubicin, vincristine, and prednisone plus Rituxan) medication.... so we've a lot to thank the NHS and the scientists who developed this med for! x”
“Diagnosed with Rheumatoid Arthritis in 1997. Failed Enbrel and Humira with hives, itching. Tried Orencia but their patient program and delivering meds was a huge disappointment (IV med only available at the time). MTX caused my liver enzymes to go nuts. Started Rituxan in 2009. My results were atypical. Rituxan is my liquid gold with a platinum price tag! A few weeks after my 2nd infusion, I felt incredible. I started running and biking. I lost 83 lbs in 4 months. I went from 235lbs of prednisone, sedentary and having 3 kids increased weight to a healthy 152lbs. I wasnt fatigued. For the first time in 19 years I was in remission while not pregnant. Not for everybody, but great for me.”
Rituxan (rituximab): “I had my first round 6 months ago sitting here starting my 2nd round as we speak. No side effects and even though my joints are still swollen I feel so much better. My dr is hopeful that this round will help with the inflammation. I'll get my 2nd dose with this round in 2 weeks!! I'm hopeful and thankful”
Rituxan (rituximab): “I’ve been on Rituxan infusions two to three times a year for 10 years. My RA symptoms are virtually non-existent. Don’t want to change meds/therapies. Tried Enbrel with methotrexate, remicade with methotrexate. None of the above gave me relief until Rituxan!”
Rituxan (rituximab): “I’m sensitive & allergic to more meds than not. I was diagnosed with RA 10 years ago @ 35 years old. We tried everything, and decided on retuxin, which scared me, but I’m so grateful I tried it! First one was very uncomfortable, I can’t take any steroids (very allergic) so I rely on Benadryl IV. I had a mild reaction toward the end, felt bad for days. Went 2 weeks later, same thing. I thought, I’m not doing this if I’m going to feel rubbish for 2 weeks. Almost exactly 4 months later, I started feeling all the fun stuff that had gone with RA. I had forgotten how I typically felt. It worked very quickly on me, and has only gotten better. I went to my doc, she said, you’re a 4 month person. Personally, retuxin was the starting point of a complete life shift. I felt better, which gave me energy, which allowed me to slowly start going to the gym, which goes hand in hand with eating clean. It has been a life changing medication for me.”
- Are lung nodules common after Bendeka & Rituxan therapy?
- What is the difference between Rituxan and Rituxan Hycela?
“I’ve had RA since approximately 1986. Been on Riduara, Minocycline and Methotrexate (which I absolutely hated!). In 2000, I started infusions. Remicade for 14 years and then just stopped working. Tried Orencia for three months - never worked. Rheumatologist put me on Actrema - some success for about 18 months and then it quit working altogether. In 2016, my Rheumatologist put me on Rituxan. I’m on a 16-week/2 week cycle. It’s been a great. I sometimes have trouble sleeping the night of my infusion (due to Solumedrol I have to take with it) and then really fatigued for a couple of days after - but I’ll take it. My joints seldom hurt, never swell - I generally feel fine. As with any biologic - I have to be careful not to catch anything (even a simple cold can knock me on my butt) - but I’ve been dealing with that issue for many years. Overall - I’m happy with the results.”
Rituxan (rituximab): “I had first infusion with no problems during administration but 2 weeks after I had to go to the E.R. with a heart arrhythmia and had to have my heart shocked back into normal rhythm. Two days later had second infusion with no problems during administration. 2 weeks later same thing...back to the E.R....heart shocked back into rhythm . Heart rate was stuck at 150 bpm. Had to be put in hospital for 4 days to be given an anti - arrhythmic drug that can also cause a fatal arrhythmia. So I would be cautious if you have any type of heart problem prior to taking Rituxan. I will not ever take it again.”
Rituxan (rituximab): “I have Rheumatoid Arthritis for the last 26 years tried numerous drugs for it methotrexate hydrochloride gold injections enbrel but had really bad side effects then Consultant put me on Rituximab 10 years a go I feel much better have less joint pain. I get itchy skin especially after a shower have to take an Antihistamine tablet sometimes headaches but I cope with all that it’s worth it I am thankful for that drug it really does help”
“Having had 2 infusions within 2 weeks of each other twice a year for the last 4 yrs it has to be said that it took a while for it to work, along with methotrexate and prednisolone but once kicked in it has improved my condition lots. You do get a feeling of a cold coming on to begin with but without doubt it has been the best medication by far. Although having tried HJumira it gave me pneumonia, 11 yrs of medicine mixtures rituximab is by far the best.”
“I am sat having my 10th cycle, 1st infusion of rituximab. Sleepy while having infusions otherwise no side effects. Previously I could not walk or look after myself. I had no quality of life. Now enjoying life with a little help. My rheumatoid hasn't gone completely but is more manageable to deal with. Not pain, or inflammation free but much better than I was. I know the side effects can sound very scary but discuss this with your consultant or specialist nurse. They are very helpful, very informative and understanding. They do not know the long term side effects of this drug but more importantly I can now live a life as before I was just existing. Try not to be daunted, ask, ask, ask and don't be afraid to try new drugs they might help”
“I was previously on Remicade that put me into remission for a few years. I wanted to have a child so I had to discontinue all medicines. I was still in remission so all was fine until a year ago when my hip just gave out. Needless to say, I am too young for hip surgery so my RA doctor recommended Rituximaub. I had my first does 3 days ago. I had a bad reaction after the rate was increased but after another dose of Benadryl and slowing down the medicines, all was fine. I have had no pain in my hip and feel great besides the grogginess from the Benadryl. My second dose is in 2 weeks and I hope that my pain will be gone (for at least 6 months). To God be the Glory!”
“I had my very first infusion of Rituxan today, I feel like I have tried EVERYTHING. I've had Enbrel, Orencia, Humira, Xeljanz, Methotrexate, Remicade. All thumbs up so far. The infusion experience was great. I feel better but we also pushed Solumedrol steroids so that could be why. Crossing my fingers for no latent side effects and good results. Will try to check back in two weeks after second infusion.”
“Started Rituximab infusions 7th and 21st March 2019 no problems then. 6 weeks later massive skin infection scratching and itching. Tried self help with anti-histamine and skin cream. Could not contact anyone at Rheumatology, contacted own GP put on Anti-biotics and Steroid cream. On 11th June check up with Reumatology nurse now suspect Cellulitus, contact own GP as soon as possible. GP prescribed more Anti-biotics. Now it's 8 weeks on and still scratching. When will this nightmare end? I wish I had never got involved with Rituximab.”
“I'm not sure what to think of this drug. I had to stop working in Nov 2018 as the disease (which was in my hands and feet) had attacked my left hip and then knee leaving me unable to walk. This is my eighth drug in four years as NOTHING has worked at all and the side effects were a horror show. Do far I have used hydroxychloroquine, sulfasalazine, methotrexate, Arava, Inflectra, Xeljanz, Kevzara. After my first infusion with rituximab on Dec 12 I had three days of pure bliss. I was in remission...or so I thought. I was pain free for the first time in 4 years .The evening of the third day the pain in my left hip started back and got worse daily. After waiting 4 weeks for the second infusion, I had three hours of relief on the second day after treatment. Since then it has been straight downhill with the pain going back into my knee. I know that Rituxan can take a while to work but I am declining daily...and losing hope.”
“This is my second infusion and I am feeling quite nauseous and head aching but know this will pass had an extremely bad headache last night but the relief from the pain has been incredible. Have been on Enbrel cimzia sllalazapirin plaquenil arava am still on prednisone and methotrexate as well as Celebrex but the relief I have had since having my first infusion is like a dream come true I had results within the first few days so there is hope out there .... I can walk a lot easier can actually use my hands which was just so painful... My life is back...don't give up”
“Diagnosed with RA March 2014. Disease fast tracked through me and rendered me unable to walk by April 2015. Have had all oral DMRADs plus Enbrel which made no difference. I was suffering immense pain and could barely leave the house. Had first Rituximab infusion Sept 2015 second 2 weeks later. Zero side effects. It has taken 10 weeks for me to feel any effect but I am now walking unaided and feel so much better. I can drive, have a bath and live a normal life again. I live in Scotland and my drugs are paid for by our NHS. I have great support from the entire Rheumatology team since being diagnosed.”
This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.
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