Rituximab Alternatives Compared
| Rituximab Remove Rituximab from your drug comparison | Methotrexate Remove Methotrexate from your drug comparison | Enbrel Remove Enbrel from your drug comparison |
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| Rituximab Remove Rituximab from your drug comparison | Methotrexate Remove Methotrexate from your drug comparison | Enbrel etanercept Remove Enbrel from your drug comparison | ||||||||||||||||
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Prescribed for Diffuse Large B-Cell Lymphoma, Granulomatosis with Polyangiitis, Follicular Lymphoma, Chronic Lymphocytic Leukemia, Non-Hodgkin's Lymphoma, Microscopic polyangiitis, Pemphigus... View more |
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Enbrel is a subcutaneous injection that is usually self-administered once or twice a week for inflammatory conditions such as rheumatoid arthritis, psoriasis, psoriatic arthritis, or ankylosing... View more |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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See the full rituximab side effects document. |
Commonly reported side effects include: increased liver enzymes. See the full methotrexate side effects document. |
Common side effects include: infection, injection site reaction. See the full Enbrel side effects document. |
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Pricing and Coupons* Prices are without insurance |
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all methotrexate prices |
View all Enbrel prices |
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Generic Availability |
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No |
Yes (this medicine) |
No |
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Dosage Form(s) Available |
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Brand Names |
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| Riabni, Rituxan, Ruxience, Truxima | Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Trexall, Xatmep | Other etanercept brands include: Erelzi, Eticovo | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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59.8 hours |
12 hours |
300 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 127 drugs are known to interact with rituximab:
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A total of 597 drugs are known to interact with methotrexate:
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A total of 391 drugs are known to interact with Enbrel:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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November 26, 1997 |
December 07, 1953 |
November 02, 1998 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.