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Medications for Osteoarthritis

Other names: Arthritis, Osteoarthritis; Degenerative Arthritis; Degenerative joint disease; DJD; Gonarthrosis; Hypertrophic Osteoarthritis; Joint Pain; OA; Osteoarthrosis; Sacroiliac Arthritis

What is Osteoarthritis:  Osteoarthritis is a chronic disease causing deterioration of the joint cartilage (the softer parts of bones, which cushion their connections to each other) and the formation of new bone (bone spurs) at the margins of the joints.

Medications to treat Osteoarthritis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Celebrex C N 57 reviews
7.0

Generic name: celecoxib systemic

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
meloxicam C N X 123 reviews
7.0

Generic name: meloxicam systemic

Brand names:  Mobic, Vivlodex

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Mobic C N X 45 reviews
7.0

Generic name: meloxicam systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Voltaren D N X 27 reviews
9.0

Generic name: diclofenac systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Voltaren Gel C N 49 reviews
8.0

Generic name: diclofenac topical

Drug class: topical non-steroidal anti-inflammatories

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
diclofenac D N X 70 reviews
8.0

Generic name: diclofenac systemic

Brand names:  Voltaren, Cataflam, Zorvolex, Voltaren-XR

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
naproxen C N X 35 reviews
7.0

Generic name: naproxen systemic

Brand names:  Aleve, Naprosyn, Anaprox, Naprelan, Aflaxen, All Day Pain Relief, All Day Relief, Anaprox-DS, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Cymbalta C N X 22 reviews
7.0

Generic name: duloxetine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
ibuprofen C N X 3 reviews
7.0

Generic name: ibuprofen systemic

Brand names:  Advil, Motrin, IBU, A-G Profen, Actiprofen, Addaprin, Advil Liqui-Gels, Genpril, Haltran, Ibu-4, Ibu-6, Ibu-8, IBU-200, Ibu-Tab, Midol IB, Motrin IB, Nuprin, Proprinal, Q-Profen

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Arthrotec X N X 19 reviews
8.0

Generic name: diclofenac / misoprostol systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
chondroitin / glucosamine N N 4 reviews
6.0

Generic name: chondroitin / glucosamine systemic

Brand names:  Osteo Bi-Flex, Cosamin DS, Schiff Move Free, Cidaflex, Glucoten, OptiFlex Complete, Pryflex, Relamine

Drug class: nutraceutical products

For consumers: interactions, side effects

 
Aleve C N X 5 reviews
6.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

 
Vimovo C N X 9 reviews
8.0

Generic name: esomeprazole / naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Cataflam D N X 2 reviews
9.0

Generic name: diclofenac systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
celecoxib C N 61 reviews
7.0

Generic name: celecoxib systemic

Brand name:  Celebrex

Drug class: cox-2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Lodine C N X 6 reviews
9.0

Generic name: etodolac systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Medrol Dosepak C N 2 reviews
9.0

Generic name: methylprednisolone systemic

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

 
Tylenol with Codeine #3 C M X 3 reviews
8.0

Generic name: acetaminophen / codeine systemic

Drug class: narcotic analgesic combinations

For consumers: dosage, interactions, side effects

 
Advil C N X Add review
5.0

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Naprosyn C N X 5 reviews
6.0

Generic name: naproxen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
nabumetone C N X 11 reviews
6.0

Generic name: nabumetone systemic

Brand name:  Relafen

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Relafen C N X 5 reviews
7.0

Generic name: nabumetone systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
aspirin N N X 1 review
6.0

Generic name: aspirin systemic

Brand names:  Ecotrin, Arthritis Pain, Aspergum, Aspiritab, Aspirtab, Bayer Aspirin, Bufferin Low Dose, Easprin, Ecpirin, Entercote, Fasprin, Genacote, Halfprin, Norwich Aspirin

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
etodolac C N X 14 reviews
7.0

Generic name: etodolac systemic

Brand names:  Lodine, Lodine XL

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Motrin C N X 1 review
8.0

Generic name: ibuprofen systemic

Drug class: nonsteroidal anti-inflammatory agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
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Alternative treatments for Osteoarthritis

The following products are considered to be alternative treatments or natural remedies for Osteoarthritis. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Osteoarthritis.

Learn more about Osteoarthritis

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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