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Hyaluronan Dosage

Medically reviewed by Last updated on Dec 7, 2018.

Applies to the following strengths: 30 mg/2 mL; 88 mg/4 mL; 24 mg/3 mL

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Osteoarthritis

2 mL intraarticularly into the knee once a week for 3 to 4 weeks.

If joint effusion is present, it should be removed before injection. A new syringe should be used for the injection.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


Hyaluronan is contraindicated in patients who are allergic to avian products, feathers, and egg products.

Intraarticular injections are contraindicated in patients with skin diseases and a history of, or existing, infections at the injection site.

Disinfectants containing quaternary ammonium salts will cause precipitation and should not be used for skin preparation.

The effectiveness of a single treatment cycle of less than 3 injections has not been established.

The safety and effectiveness of repeat treatment cycles have not been established.

The safety and effectives of hyaluronan in joints other than the knee, or with concurrent other intraarticular injections has not been established.

Patients should be advised to avoid any strenuous or prolonged (greater than 1 hour) weightbearing activities for 48 hours after the injection.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).


Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.