Skip to Content

Meloxicam Side Effects

In Summary

More frequently reported side effects include: abdominal pain, edema, and anemia. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to meloxicam: oral suspension, oral tablet

In addition to its needed effects, some unwanted effects may be caused by meloxicam. In the event that any of these side effects do occur, they may require medical attention.

Severity: Major

You should check with your doctor immediately if any of these side effects occur when taking meloxicam:

Less common:
  • Arm, back, or jaw pain
  • bleeding gums
  • bloating
  • blood in the urine
  • blurred vision
  • burning upper abdominal or stomach pain
  • canker sores
  • chest tightness or heaviness
  • chills
  • cloudy urine
  • cough
  • cramping
  • dark urine
  • decreased frequency or amount of urine
  • difficult or labored breathing
  • dilated neck veins
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • general tiredness and weakness
  • headache
  • hives or welts
  • increased blood pressure
  • increased sensitivity of the skin to sunlight
  • increased thirst
  • irregular breathing
  • itching, redness, or other discoloration of the skin
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • loss of appetite
  • lower side or back pain
  • noisy breathing
  • pain or discomfort in the arms, jaw, back, or neck
  • painful or difficult urination
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pinpoint red or purple spots on the skin
  • pounding in the ears
  • redness, soreness, or itching skin
  • seizures
  • severe and continuing nausea
  • severe sunburn
  • shakiness in the legs, arms, hands, or feet
  • skin blisters
  • sore throat
  • sores, ulcers, or white spots on the lips or tongue or inside the mouth
  • sores, welting, or blisters
  • stomach bloating, burning, cramping, tenderness, or pain
  • sweating
  • swelling or puffiness of the face
  • swollen glands
  • trembling or shaking of the hands or feet
  • trouble with breathing
  • unusual bleeding or bruising
  • upper right abdominal or stomach pain
  • watery or bloody diarrhea
  • weight gain or loss
  • yellow eyes or skin
Rare:
  • Area rash
  • blistering, peeling, or loosening of the skin
  • bloody or black, tarry stools
  • clay-colored stools
  • cold, clammy skin
  • continuing vomiting
  • cough or hoarseness
  • cracks in the skin
  • difficulty with swallowing
  • fast, weak pulse
  • fever with or without chills
  • greatly decreased frequency of urination or amount of urine
  • joint or muscle pain
  • lightheadedness
  • loss of heat from the body
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • red, swollen skin
  • scaly skin
  • severe stomach pain
  • shortness of breath
  • tightness in the chest
  • unpleasant breath odor
  • unusual tiredness or weakness
  • vomiting of blood or material that looks like coffee grounds
  • wheezing
Incidence not known:
  • Difficulty with speaking
  • double vision
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • pains in the chest, groin or legs, especially the calves
  • severe headaches of sudden onset
  • slow speech
  • sudden loss of coordination
  • sudden onset of shortness of breath for no apparent reason
  • sudden onset of slurred speech
  • sudden vision changes

If any of the following symptoms of overdose occur while taking meloxicam, get emergency help immediately:

Symptoms of overdose:
  • Blue lips, fingernails, or skin
  • convulsions (seizures)
  • pain in the chest, upper stomach, or throat
  • severe stomach pain
  • skin rash
  • slow or fast heartbeat
  • swelling around the eyes, face, lips, or tongue
  • weight gain (rapid)

Severity: Minor

Some of the side effects that can occur with meloxicam may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Diarrhea
  • gas
  • heartburn
  • indigestion
Less common or rare:
  • Abdominal or stomach pain
  • abnormal dreaming
  • anxiety
  • appetite increased
  • bad, unusual, or unpleasant after taste
  • belching
  • bloated or full feeling
  • burning feeling in the chest or stomach
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • burning, dry, or itching eyes
  • change in taste
  • changes in vision
  • confusion
  • constipation
  • continuing ringing or buzzing or other unexplained noise in the ears
  • decreased urination
  • discharge
  • discouragement
  • dry mouth
  • excess air or gas in the stomach
  • excessive tearing
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • general feeling of discomfort or illness
  • hair loss
  • hearing loss
  • hot flushes
  • irritability
  • loss of interest or pleasure
  • nausea or vomiting
  • nervousness
  • pain or burning in the throat
  • rapid breathing
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • sensation of spinning
  • sleepiness
  • stomach upset
  • sunken eyes
  • tenderness in the stomach area
  • thinning of the hair
  • thirst
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • wrinkled skin

For Healthcare Professionals

Applies to meloxicam: oral capsule, oral suspension, oral tablet

General

The most frequently reported side effects were diarrhea, upper respiratory tract infections, dyspepsia, nausea, abdominal discomfort, and influenza-like symptoms.[Ref]

Gastrointestinal

Very common (10% or more): Dyspepsia, nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea
Common (1% to 10%): Abdominal discomfort, gastrointestinal (GI) irritation, aggravated dyspepsia, eructation, gastroesophageal reflux disease, upper abdominal pain
Uncommon (0.1% to 1%): Occult or macroscopic GI hemorrhage, gastritis, stomatitis
Rare (0.01% to 0.1%): Colitis, gastroduodenal ulcer, esophagitis
Very rare (less than 0.01%): GI perforation
Frequency not reported: Dry mouth, duodenal ulcer, gastric ulcer, gastritis, hematemesis, hemorrhagic duodenal ulcer, hemorrhagic gastric ulcer, intestinal perforation, melena, pancreatitis, perforated duodenal ulcer, perforated gastric ulcer, stomatitis ulcerative[Ref]

Cardiovascular

Common (1% to 10%): Hypertension
Uncommon (0.1% to 1%): Flushing
Rare (less than 0.1%): Palpitations
Frequency not reported: Hot flushes, angina pectoris, cardiac failure, hypotension, myocardial infarction, vasculitis, arrhythmia, palpitation, tachycardia, shock, cardiac failure[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache, carpel tunnel syndrome
Uncommon (0.1% to 1%): Somnolence
Frequency not reported: Syncope, convulsions, paresthesia, tremor, taste perversion[Ref]

Respiratory

Common (1% to 10%): Pharyngitis, upper respiratory tract infection, coughing, nasopharyngitis, bronchitis, sinusitis, laryngitis, pleuritic pain, dyspnea, rhinitis
Rare (less than 0.1%): Asthma
Frequency not reported: Bronchospasm[Ref]

Other

Common (1% to 10%): Accident household, edema, fall, influenza-like symptoms, pain, peripheral edema, gravitational edema, fatigue, ear disorder, vertigo, fall
Frequency not reported: Face edema, fever, malaise, weight decreased, weight increased, tinnitus
Postmarketing reports: Meningitis[Ref]

Hematologic

Common (1% to 10%): Anemia
Rare (0.01% to 0.1%): Blood count abnormal, leukopenia, thrombocytopenia
Very rare (less than 0.01%): Agranulocytosis[Ref]

Dermatologic

Common (1% to 10%): Rash, pruritus, erythematous rash, maculopapular rash, hyperhidrosis, purpura
Uncommon (0.1% to 1%): Angioedema
Rare (0.01% to 0.1%): Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria
Very rare (less than 0.01%): Dermatitis bullous, erythema multiforme
Frequency not reported: Alopecia, bullous eruption, exfoliative dermatitis, photosensitivity reaction, sweating increased[Ref]

Hypersensitivity

Common (1% to 10%): Hypersensitivity
Uncommon (0.1% to 1%): Allergic reactions
Frequency not reported: Anaphylactoid reaction[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia, aggravated arthralgia, joint crepitation, joint effusion, joint swelling, back pain, osteoarthritis, pain in extremity, arthritis, bursitis, muscle spasms, myalgia, rheumatoid arthritis[Ref]

Genitourinary

Common (1% to 10%): Micturition frequency, urinary tract infection, hematuria
Frequency not reported: Acute urinary retention[Ref]

Hepatic

Uncommon (0.1% to 1%): Liver function disorder, ALT increased, AST increased, bilirubinemia
Very rare (less than 0.01%): Hepatitis
Frequency not reported: GGT increased, jaundice, liver failure[Ref]

Psychiatric

Common (1% to 10%): Insomnia
Rare (less than 0.1%): Nightmares, mood alterations
Frequency not reported: Abnormal dreaming, anxiety, confusion, depression, nervousness, disorientation[Ref]

Renal

Very rare (less than 0.01%): Acute renal failure, papillary necrosis, acute tubular necrosis
Frequency not reported: Albuminuria, BUN increased, creatinine increased, interstitial nephritis, renal failure[Ref]

Metabolic

Common (1% to 10%): Dehydration, appetite increased
Uncommon (0.1% to 1%): Sodium retention, hyperkalemia, water retention[Ref]

Ocular

Common (1% to 10%): Cataract
Rare (less than 0.1%): Visual disturbances, conjunctivitis, blurred vision
Frequency not reported: Abnormal vision[Ref]

References

1. "Product Information. Mobic (meloxicam)" Boehringer-Ingelheim, Ridgefield, CT.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. MHRA. Medicines and Health Regulatory Agency "MHRA Drug Safety Update. Available from: URL: http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate."

Not all side effects for meloxicam may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide