Generic Name: cangrelor (Intravenous route)
Medically reviewed by Drugs.com. Last updated on Nov 21, 2019.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Platelet Aggregation Inhibitor
Pharmacologic Class: ADP-Induced Aggregation Inhibitor
Uses for Kengreal
Cangrelor injection is used in patients undergoing percutaneous coronary intervention (PCI) to lower the risk of blood clots and heart attack.
A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Cangrelor reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together. This effect of cangrelor may also increase the chance of serious bleeding in some people.
This medicine is to be given only by or under the supervision of your doctor.
Before using Kengreal
Appropriate studies have not been performed on the relationship of age to the effects of cangrelor injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cangrelor injection in the elderly.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
- Amtolmetin Guacil
- Choline Salicylate
- Dabigatran Etexilate
- Flufenamic Acid
- Mefenamic Acid
- Niflumic Acid
- Nimesulide Beta Cyclodextrin
- Protein C
- Salicylic Acid
- Sodium Salicylate
- Tiaprofenic Acid
- Tolfenamic Acid
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
- Bleeding, active—Should not be used in patients with these conditions.
Proper use of Kengreal
A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins. It is given before the start of PCI.
Precautions while using Kengreal
It is very important that your doctor check you closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects. Blood tests may be needed to check for unwanted effects.
This medicine may increase your chance of bleeding and bruising. Check with your doctor right away if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin.
Kengreal side effects
Check with your doctor or nurse immediately if any of the following side effects occur:
- Abdominal or stomach pain or swelling
- back pain
- black, tarry stools
- blood in the eyes
- blood in the urine
- bruising or purple areas on the skin
- coughing up blood
- decreased alertness
- joint pain or swelling
- Difficult or labored breathing
- tightness in the chest
- difficulty with swallowing
- fast heartbeat
- hives, itching, or rash
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- noisy breathing
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- unusual tiredness or weakness
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More about Kengreal (cangrelor)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- Drug class: platelet aggregation inhibitors
- FDA Approval History