Generic Name: ticagrelor (tye KA grel or)
Brand Name: Brilinta (ticagrelor), Brilinta
What is ticagrelor?
Ticagrelor prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery.
Ticagrelor may also be used for purposes not listed in this medication guide.
You should not use ticagrelor if you have any active bleeding or a history of bleeding in the brain. Do not use ticagrelor just before heart bypass surgery.
Ticagrelor may cause you to bleed more easily, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop, black or bloody stools, red or pink urine, or if you cough up blood or vomit that looks like coffee grounds.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with ticagrelor.
Do not stop taking ticagrelor without first talking to your doctor, even if you have signs of bleeding. Stopping ticagrelor may increase your risk of a heart attack or stroke.
Before taking this medicine
You should not use ticagrelor if you are allergic to it, or if you have:
any active bleeding; or
a history of bleeding in the brain (such as from a head injury).
Tell your doctor if you have ever had:
a surgery or bleeding injury;
a stomach ulcer or colon polyps;
liver disease; or
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breast-feed while using ticagrelor.
How should I take ticagrelor?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Ticagrelor is taken together with aspirin. Use these medicines exactly as directed.
Do not take more aspirin than your doctor has prescribed. Taking too much aspirin can make ticagrelor less effective.
Take ticagrelor at the same time each day, with or without food.
If you cannot swallow a tablet whole, crush the pill and mix it with water. Stir and drink this mixture right away. Add more water to the glass, stir, and drink right away.
Ticagrelor keeps your blood from coagulating (clotting) and can make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have any bleeding that will not stop.
To prevent excessive bleeding, you may need to stop using ticagrelor for a short time before a surgery, medical procedure, or dental work. Any healthcare provider who treats you should know that you are taking ticagrelor.
Do not stop taking ticagrelor without first talking to your doctor, even if you have signs of bleeding. Stopping the medicine could increase your risk of a heart attack or stroke.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause excessive bleeding.
What should I avoid while taking ticagrelor?
Drinking alcohol while taking aspirin can increase your risk of stomach bleeding.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
While taking ticagrelor with aspirin, avoid using medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to aspirin (such as salicylates, ibuprofen, ketoprofen, or naproxen). Taking certain products together can cause you to get too much aspirin which can increase your risk of bleeding.
Ticagrelor side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
nosebleeds, or any bleeding that will not stop;
shortness of breath even with mild exertion or while lying down;
easy bruising, unusual bleeding, purple or red spots under your skin;
red, pink, or brown urine;
black, bloody, or tarry stools; or
coughing up blood or vomit that looks like coffee grounds.
Common side effects may include:
shortness of breath.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect ticagrelor?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Tell your doctor about all your current medicines. Many drugs can affect ticagrelor, especially:
antiviral medicine to treat HIV or AIDS;
a blood thinner;
heart or blood pressure medication;
seizure medicine; or
This list is not complete and many other drugs may affect ticagrelor. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 3.01.
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More about ticagrelor
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- En Español
- 62 Reviews
- Drug class: platelet aggregation inhibitors
- FDA Alerts (2)
Other brands: Brilinta