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Alendronate Dosage

Medically reviewed by Last updated on Aug 3, 2023.

Applies to the following strengths: 35 mg; 70 mg; 40 mg; 5 mg; 10 mg; 70 mg/75 mL

Usual Adult Dose for Osteoporosis

10 mg orally once a day or 70 mg orally once a week

For the Treatment of Glucocorticoid-Induced Osteoporosis: 5 mg orally once a day
For the Treatment of Glucocorticoid-Induced Osteoporosis in Postmenopausal Women Not Receiving Estrogen: 10 mg orally once a day


Uses: For the treatment of osteoporosis in postmenopausal women, men with osteoporosis, and men and women with glucocorticoid-induced osteoporosis receiving glucocorticoids in a daily dose equivalent to 7.5 mg or greater of prednisone who have low bone mineral density.

Usual Adult Dose for Prevention of Osteoporosis

5 mg orally once a day or 35 mg orally once a week


Use: Prevention of osteoporosis in postmenopausal women

Usual Adult Dose for Paget's Disease

40 mg orally once a day for 6 months


Use: Treatment of Paget's disease of bone

Renal Dose Adjustments

CrCl 35 mL/min or more: No adjustment recommended
CrCl less than 35 mL/min: Not recommended

Liver Dose Adjustments

No adjustment recommended


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

Recommendations for Calcium and Vitamin D Supplementation:

Missed Doses:



Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.