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Atelvia

Generic Name: risedronate (rih SED ro nayt)
Brand Names: Actonel, Atelvia

What is Atelvia?

Atelvia (risedronate) is a bisphosphonate medicine that slows bone loss while increasing bone mass, which may prevent bone fractures.

Atelvia is a prescription medicine used in women to treat osteoporosis caused by menopause.

It is not known how long Atelvia works for the treatment and prevention of osteoporosis. You should see your doctor regularly to determine if this medicine is still right for you.

Important information

You should not take Atelvia if you have problems with your esophagus, or low levels of calcium in your blood.

Do not take this medicine if you cannot sit upright or stand for at least 30 minutes after taking the medicine.

Atelvia can cause serious problems in the stomach or esophagus. Stop using this medicine and call your doctor at once if you have chest pain, new or worsening heartburn, or pain when swallowing.

Also call your doctor if you have muscle spasms, numbness or tingling (in hands and feet or around the mouth), new or unusual hip pain, or severe pain in your joints, bones, or muscles.

Atelvia side effects

Get emergency medical help if you have signs of an allergic reaction to Atelvia (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Stop using Atelvia and call your doctor at once if you have:

  • chest pain, new or worsening heartburn;

  • difficulty or pain when swallowing;

  • pain or burning under the ribs or in the back;

  • severe heartburn, burning pain in your upper stomach, or coughing up blood;

  • new or unusual pain in your thigh or hip;

  • jaw pain, numbness, or swelling;

  • severe joint, bone, or muscle pain; or

  • low calcium levels - muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes).

Common Atelvia side effects may include:

  • heartburn, indigestion;

  • stomach pain, diarrhea;

  • back pain, joint pain, muscle pain; or

  • flu-like symptoms.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Side Effects (complete list)

Before taking this medicine

You should not take Atelvia if you are allergic to risedronate, or if you have:

  • low levels of calcium in your blood (hypocalcemia); or

  • problems with the muscles in your esophagus (the tube that connects your mouth and stomach).

Do not take Atelvia if you cannot sit upright or stand for at least 30 minutes. Risedronate can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

  • trouble swallowing;

  • problems with your stomach or digestion;

  • hypocalcemia;

  • a dental problem (you may need a dental exam before you begin taking Atelvia);

  • kidney disease; or

  • any condition that makes it hard for your body to absorb nutrients from food (malabsorption).

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Atelvia, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Atelvia will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether risedronate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take Atelvia?

Take Atelvia exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take the tablet just after breakfast, with at least 4 ounces of water.

Swallow Atelvia tablets whole. Do not chew, cut, or crush the tablets before swallowing. If you cannot swallow the tablets whole, tell your doctor. You may need a different medicine.

For at least 30 minutes after taking Atelvia:

  • Do not lie down or recline. You may sit, stand or walk, and do normal activities like reading.

  • Do not take any other medicine including vitamins, calcium, iron, antacids, or laxatives.

Take this medicine at the same time each day or on the same day each week or each month (depending on your dosing schedule).

Pay special attention to your dental hygiene while taking Atelvia. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using risedronate.

Atelvia is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat. Keep unused effervescent tablets in the foil blister pack.

Your doctor will determine how long to treat you with this medicine. Atelvia is often given for only 3 to 5 years.

Atelvia dosing information

Usual Adult Dose for Osteoporosis:

Treatment of Postmenopausal Osteoporosis:
Delayed release:
-35 mg orally once a week


Comments:
-Refer to administration advice for details on how to take this drug.
-Reevaluate bisphosphonate therapy periodically.
-Patients treated with glucocorticoids should receive adequate amounts of calcium and vitamin D.

Uses:
-Treatment to reduce the incidence of vertebral fractures and composite endpoint of nonvertebral osteoporosis-related fractures in postmenopausal women.

Dosage Information (comprehensive)

What happens if I miss a dose?

If you forget to take Atelvia on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular weekly schedule on your chosen dose day. Do not take 2 doses in one day.

What happens if I overdose?

Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.

What should I avoid while taking Atelvia?

Avoid taking any other medicines for at least 30 minutes after taking Atelvia. This includes vitamins, calcium, iron, antacids, or laxatives. Some medicines can make it harder for your body to absorb risedronate.

Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely.

Avoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss.

What other drugs will affect Atelvia?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • aspirin;

  • iron supplements;

  • antacids, laxatives; or

  • NSAIDs (nonsteroidal anti-inflammatory drugs) - ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may interact with risedronate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Talk with your doctor about the best dosing schedule for your other medicines.

Where can I get more information?

  • Your pharmacist can provide more information about Atelvia.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Atelvia only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2017 Cerner Multum, Inc. Version: 12.01.

Last reviewed: October 11, 2017
Date modified: November 12, 2017

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