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Alendronate Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Alendronate Evenity (romosozumab) Calcium / vitamin d
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Alendronate Evenity (romosozumab) Calcium / vitamin d
Prescription only

Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. Dosage instructions, including remaining upright for at least 30 minutes and taking with a... View more

Prescription only

Prescribed for Osteoporosis. Evenity may also be used for purposes not listed in this medication guide.

Over-the-counter

Prescribed for Osteoporosis, Dietary Supplementation. Calcium / vitamin d may also be used for purposes not listed in this medication guide.

More about Alendronate More about Evenity (romosozumab) More about Calcium / vitamin d
Ratings & Reviews

Alendronate has an average rating of 2.8 out of 10 from a total of 185 ratings on Drugs.com. 17% of reviewers reported a positive effect, while 78% reported a negative effect.

Evenity has an average rating of 6.6 out of 10 from a total of 76 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 18% reported a negative effect.

Calcium / vitamin d has an average rating of 7.5 out of 10 from a total of 12 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 8% reported a negative effect.

View all 185 reviews

View all 76 reviews

View all 12 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Alendronate side effects

View all Evenity side effects

View all Calcium / vitamin d side effects
Drug Class
Generic Availability

Lower cost generic

N/A

Lower cost generic
Pricing and Coupons * Prices are without insurance
Quantity 4 tablet
Strength 70 mg
Per unit* $4.26 - $8.44
Cost* $17.02 - $33.77

View all Alendronate prices

Quantity 2.34 mL
Strength 105 mg/1.17 mL
Per unit* $1,203.60
Cost* $2,816.42

View all Evenity prices

We could not find an exact match for this medicine. Try searching the Price Guide directly.

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Dosage Forms
  • Oral solution
  • Oral tablet
  • Subcutaneous solution

N/A
Brand Names
Binosto, Fosamax

N/A

 Calcarb with D, Calcet, Calcet Petites, Calcio Del Mar, Calcitrate with D, Calcium 600 D, Caltrate 600 with D Plus Soy, Caltrate 600+D, Caltrate Colon Health, Caltrate Gummy Bites, Caltro with Vitamin D, Calvite P, Chewable Calcium with Vitamin D, Citracal + D, Citracal Calcium Gummies, Citracal Calcium Pearls, Citracal Maximum, Citracal Petites, Citracal Plus Heart Health, Citracal Regular, Citracal Regular 250 mg + D, Citracal Slow Release 1200, Citrus Calcium with Vitamin D, Dical Captabs, Dical-D, Dicalphos plus D, Os-Cal 500 Chewable, Os-Cal Calcium+D3, Os-Cal Extra D3, Oysco 500 with D, Oyster Shell Calcium with Vitamin D, Oyster-D, Oystercal-D, Posture-D H/P, Risacal-D, UPCal D, Wellesse Liquid Calcium with Vitamin D View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

N/A

307.2 hours

N/A
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out
Drug Interactions

A total of 118 drugs are known to interact with Alendronate:

  • 3 major drug interactions (8 brand and generic names)
  • 110 moderate drug interactions (1897 brand and generic names)
  • 5 minor drug interactions (45 brand and generic names)

A total of 47 drugs are known to interact with Evenity:

  • 1 major drug interactions (2 brand and generic names)
  • 46 moderate drug interactions (260 brand and generic names)

A total of 284 drugs are known to interact with Calcium / vitamin d:

  • 18 major drug interactions (70 brand and generic names)
  • 222 moderate drug interactions (1811 brand and generic names)
  • 44 minor drug interactions (203 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Food may reduce the absorption of alendronate, which may lead to lower blood levels of the... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
  • Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid... View more
  • Treatment with ergocalciferol may require you to adjust your dietary intake of foods which contain... View more
Disease Interactions
First Approval Date

September 29, 1995

April 09, 2019

N/A
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources

N/A
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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