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Genacote Side Effects

Generic Name: aspirin

Note: This page contains information about the side effects of aspirin. Some of the dosage forms included on this document may not apply to the brand name Genacote.

For the Consumer

Applies to aspirin: oral capsule, oral capsule delayed release, oral capsule extended release 24 hr, oral gum, oral tablet, oral tablet chewable, oral tablet effervescent, oral tablet enteric coated, oral tablet extended release

In addition to its needed effects, some unwanted effects may be caused by aspirin (the active ingredient contained in Genacote). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking aspirin:

Incidence not known:
  • Abdominal or stomach pain, cramping, or burning
  • black, tarry stools
  • bloody or cloudy urine
  • change in consciousness
  • chest pain or discomfort
  • confusion
  • constipation
  • convulsions, severe or continuing
  • dark urine
  • decreased frequency or amount of urine
  • diarrhea
  • difficult breathing
  • drowsiness
  • fainting
  • fast breathing
  • feeling that something terrible will happen
  • fever
  • general tiredness and weakness
  • greatly decreased frequency of urination or amount of urine
  • headache
  • heartburn
  • increased thirst
  • indigestion
  • irregular heartbeat
  • light-colored stools
  • loss of appetite
  • loss of consciousness
  • lower back or side pain
  • muscle cramping and weakness
  • muscle tremors
  • nausea or vomiting
  • nervousness
  • numbness or tingling in the hands, feet, or lips
  • panic
  • rapid, deep breathing
  • restlessness
  • seizures
  • skin rash
  • stomach cramps
  • swelling of the face, fingers, or lower legs
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • upper right abdominal or stomach
  • vomiting of blood or material that looks like coffee grounds
  • weakness or heaviness of the legs
  • weight gain
  • yellow eyes and skin

Minor Side Effects

Some of the side effects that can occur with aspirin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known:
  • Acid or sour stomach
  • anxiety
  • belching
  • dizziness
  • dry mouth
  • hyperventilation
  • irritability
  • shaking
  • stomach discomfort, upset, or pain
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

For Healthcare Professionals

Applies to aspirin: compounding powder, oral capsule extended release, oral delayed release capsule, oral delayed release tablet, oral gum, oral powder for reconstitution, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet dispersible, oral tablet extended release, rectal suppository

Gastrointestinal

Common (1% to 10%): Dyspepsia,
Frequency not reported: GI bleeding, ulceration, perforation, nausea, vomiting, pancreatitis, gastric irritation, GI erosions, gastritis, melena, hematemesis, gingival bleeding[Ref]

Renal

Frequency not reported: Interstitial nephritis, papillary necrosis, renal insufficiency and failure[Ref]

Hematologic

Common (1% to 10%): Increased bleeding tendencies
Rare (0.01% to 0.1%): Aplastic anemia agranulocytosis, thrombocytopenia
Frequency not reported: Prolongation of prothrombin time, disseminated intravascular coagulation, coagulopathy, antepartum and postpartum bleeding, anemia[Ref]

Hypersensitivity

Rare (0.01% to 0.1%): Anaphylactic reactions including shock
Frequency not reported: Urticaria, angioedema, skin rashes[Ref]

Dermatologic

Uncommon (0.1% to 1%): Urticaria
Rare (0.01% to 0.1%): Steven-Johnson syndrome, Lyell's syndrome, erythema nodosum, erythema multiforme
Frequency not reported: Purpura, hives[Ref]

Hepatic

Frequency not reported: Transient elevations of hepatic enzymes, hepatitis, Reye's syndrome, hepatic insufficiency[Ref]

Metabolic

Frequency not reported: Thirst, dehydration, hyperkalemia, metabolic acidosis, respiratory alkalosis, hypoglycemia, hyperglycemia, hyperuricemia, salt and water retention[Ref]

Cardiovascular

Rare (0.01% to 0.1%): Hemorrhagic vasculitis
Frequency not reported: Dysrhythmias, hypotension, tachycardia[Ref]

Nervous system

Frequency not reported: Cerebral edema, coma headache, subdural or intracranial hemorrhage, seizures, lethargy, dizziness[Ref]

Other

Frequency not reported: Fever, hypothermia, hearing loss, tinnitus (at high doses), hearing disturbances[Ref]

Musculoskeletal

Frequency not reported: Rhabdomyolysis[Ref]

Respiratory

Frequency not reported: Hyperpnea, pulmonary edema, tachypnea, epistaxis, dyspnea, bronchospasm, asthma[Ref]

General

The more commonly experienced adverse effects include indigestion, dyspepsia, bleeding, and bruising.[Ref]

Genitourinary

Rare (0.01% to 0.1%): Menorrhagia
Frequency not reported: Proteinuria[Ref]

Psychiatric

Frequency not reported: Agitation, confusion[Ref]

References

1. "Product Information. Bayer aspirin (aspirin)." Bayer, West Haven, CT.

2. US Food and Drug Administration "TITLE 21--FOOD AND DRUGS,CHAPTER I--FOOD AND DRUG ADMINISTRATION,DEPARTMENT OF HEALTH AND HUMAN SERVICES SUBCHAPTER D--DRUGS FOR HUMAN USE,PART 341 COLD, COUGH, ALLERGY, BRONCHODILATOR, AND ANTIASTHMATIC DRUG PRODUCTS FO. Available from: URL: https://ww" ([2016, Apr 01]):

3. "Product Information. Durlaza (aspirin (acetylsalicylic acid))." New Haven Pharmaceuticals, North Haven, CT.

4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Not all side effects for Genacote may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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