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Tramadol Drug Interactions

A total of 493 drugs are known to interact with tramadol.

  • 278 major drug interactions
  • 212 moderate drug interactions
  • 3 minor drug interactions

Show all medications in the database that may interact with tramadol.

Check for interactions

Type in a drug name to check for interactions with tramadol.

Most frequently checked interactions

View interaction reports for tramadol and the medicines listed below.

Tramadol alcohol/food interactions

There is 1 alcohol/food interaction with tramadol

Tramadol disease interactions

There are 10 disease interactions with tramadol which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.