Subsys Interactions
There are 635 drugs known to interact with Subsys (fentanyl), along with 17 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 259 are major, 372 are moderate, and 4 are minor.
- View all 635 medications that may interact with Subsys
- View Subsys alcohol/food interactions (1)
- View Subsys disease interactions (17)
Most frequently checked interactions
View interaction reports for Subsys (fentanyl) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall (amphetamine / dextroamphetamine)
- amitriptyline
- amitriptyline
- baclofen
- baclofen
- Celebrex (celecoxib)
- Celebrex (celecoxib)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Dexilant (dexlansoprazole)
- Dexilant (dexlansoprazole)
- Dilaudid (hydromorphone)
- Dilaudid (hydromorphone)
- gabapentin
- gabapentin
- hydrocodone
- hydrocodone
- Klonopin (clonazepam)
- Klonopin (clonazepam)
- levothyroxine
- levothyroxine
- Norco (acetaminophen / hydrocodone)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- omeprazole
- oxycodone
- oxycodone
- tizanidine
- tizanidine
Subsys alcohol/food interactions
There is 1 alcohol/food interaction with Subsys (fentanyl).
Subsys disease interactions
There are 17 disease interactions with Subsys (fentanyl) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- fever
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
More about Subsys (fentanyl)
- Subsys consumer information
- Compare alternatives
- Reviews (12)
- Latest FDA alerts (14)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.