Acetaminophen Drug Interactions
A total of 177 drugs (1079 brand and generic names) are known to interact with acetaminophen.
- 14 major drug interactions (105 brand and generic names)
- 69 moderate drug interactions (266 brand and generic names)
- 94 minor drug interactions (708 brand and generic names)
Check for interactions with acetaminophen
Common medications checked in combination with acetaminophen
- aspirin
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- caffeine
- Calcium 600 D (calcium / vitamin d)
- codeine
- Colace (docusate)
- Cymbalta (duloxetine)
- diclofenac
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- hydrocodone
- ibuprofen
- Lasix (furosemide)
- Lyrica (pregabalin)
- meloxicam
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Milk of Magnesia (magnesium hydroxide)
- MiraLax (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- naproxen
- Nexium (esomeprazole)
- oxycodone
- prednisone
- ProAir HFA (albuterol)
- Synthroid (levothyroxine)
- tramadol
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xarelto (rivaroxaban)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
acetaminophen alcohol/food Interactions
There is 1 alcohol/food interaction with acetaminophen
acetaminophen disease Interactions
There are 3 disease interactions with acetaminophen which include:
More about acetaminophen
- Acetaminophen Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Compare Alternatives
- Support Group
- Pricing & Coupons
- 49 Reviews
- Drug class: miscellaneous analgesics
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
