Acetaminophen Interactions
There are 159 drugs known to interact with acetaminophen, along with 3 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 8 are major, 115 are moderate, and 36 are minor.
- View all 159 medications that may interact with acetaminophen
- View acetaminophen alcohol/food interactions (2)
- View acetaminophen disease interactions (3)
Most frequently checked interactions
View interaction reports for acetaminophen and the medicines listed below.
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Colace (docusate)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lasix (furosemide)
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Milk of Magnesia (magnesium hydroxide)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Norco (acetaminophen / hydrocodone)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Synthroid (levothyroxine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Acetaminophen alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen.
Acetaminophen disease interactions
There are 3 disease interactions with acetaminophen which include:
Report options
More about acetaminophen
- acetaminophen consumer information
- Compare alternatives
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- Reviews (105)
- Drug images
- Latest FDA alerts (18)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: miscellaneous analgesics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Diclofenac
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Oxycodone
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Amitriptyline
Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
