Acetaminophen Drug Interactions
A total of 169 drugs (1042 brand and generic names) are known to interact with acetaminophen.
- 14 major drug interactions (102 brand and generic names)
- 62 moderate drug interactions (251 brand and generic names)
- 93 minor drug interactions (689 brand and generic names)
Check for interactions with acetaminophen
Common medications checked in combination with acetaminophen
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Calcium 600 D (calcium / vitamin d)
- Colace (docusate)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lasix (furosemide)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Tartrate (metoprolol)
- Milk of Magnesia (magnesium hydroxide)
- MiraLax (polyethylene glycol 3350)
- Nexium (esomeprazole)
- ProAir HFA (albuterol)
- Synthroid (levothyroxine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
acetaminophen alcohol/food Interactions
There is 1 alcohol/food interaction with acetaminophen
acetaminophen disease Interactions
There are 3 disease interactions with acetaminophen which include:
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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