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Acetaminophen use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on Jan 19, 2022.

Drugs containing Acetaminophen: Paracetamol, Tylenol, Percocet, Norco, Vicodin, Fioricet, Tylenol with Codeine #3, Panadol, Lortab, Aceta, Show all 1045 »Excedrin, Ultracet, Excedrin Migraine, Vicks NyQuil Cold & Flu Nighttime Relief, Percocet 5/325, Midol, Tylenol with Codeine, Migraine Relief, Percocet 10/325, Tylenol Extra Strength, Tylenol PM, Coricidin HBP Cold & Flu, Vicks DayQuil Severe Cold & Flu, Vicks NyQuil Severe Cold & Flu, Vicks Dayquil Cold & Flu Relief, Perfalgan, Endocet, Ofirmev, Tylenol with Codeine #4, Cough & Cold Relief, Tylenol Arthritis Pain, Alka-Seltzer Plus Cold, Mapap, Dologesic, Roxicet, Arthritis Pain Relief, Esgic, Darvocet-N 50, Headache Relief, Children's Tylenol, Tylox, Sinarest, Hycet, Pamprin Multi-Symptom Menstrual Relief, Midrin, Theraflu Nighttime Severe Cold & Cough, Percocet 7.5/325, Excedrin Extra Strength, Advil Dual Action, Fioricet with Codeine, Efferalgan, Midol Complete, Theraflu Flu & Cough, Sudafed PE Cold & Cough, Lorcet, Darvocet-N 100, Panadol Osteo, Tencon, Tylenol Cold & Flu Severe, Anabar, Doliprane, Dologen, Benadryl Allergy Plus Cold, Vicodin ES, Painaid, Norel AD, Mucinex Nightshift Cold & Flu, Tylenol Sinus + Headache Day, Mucinex Fast-Max Severe Cold, Headache Relief PM, Mucus Relief Cold & Sinus Maximum Strength, Percocet 7.5/500, Altenol, Acephen, Paracetamol Almus, Panadol ActiFast, Trezix, Childrens Tylenol Cold Plus Cough, Multi Symptom Cold (Day Formula), Legatrin PM, Midol PMS Maximum Strength, Pamprin Maximum Pain, Menstrual Pain Relief, Setamol, Lemsip Max, Atasol, Infant's Tylenol, Panamax, Mapap Arthritis Pain, Pamprin Max Menstrual Pain Relief, Goody's Extra-Strength Headache Powders, Backaid Inflammatory Pain Formula, Phrenilin, Triad, Coricidin HBP Maximum Strength Flu, XL-3 Cold Medicine, Cold Medicine Plus, Daytime Cold & Flu, Pain Relief PM Extra Strength, Tylenol Sinus Severe Day, Sudafed PE Sinus Pressure + Pain, Midol Long Lasting Relief, Buckley's Complete, Tempra, Dafalgan, Migraine Formula, Margesic, Excedrin Tension Headache, Migralam, Tylenol Cold and Flu Severe Day & Night, Tylenol Cold, Pyrroxate, Coricidin D, Mucinex Sinus-Max Pressure, Pain & Cough, Comtrex Cold & Cough, Theraflu Daytime Severe Cold & Cough, Tylenol Cold Max Day, Vicks Dayquil Daytime Cold/Flu (old formulation), Amidrine, Percogesic Original Strength, Mucinex Fast-Max Night Time Cold & Flu, Anexsia, Xartemis XR, Narvox, Tylenol 8 Hour, Panadol Extend, Cipla Genpharm Paracetamol, Tylenol Regular Strength, Taminol, Pharbetol, Paracetamol Merck, Paracetamol Sandoz, Paracetamol Zydus, Cetafen, Promax, Soul Pattinson Colour Free Paracetamol Drops, Exaprin, Comtrex Acute Head Cold, Bucet, Cephadyn, Geone, Esgic-Plus, Menstrual Relief, Congestant, Triaminic Multi-Symptom Fever, Codral Cold and Flu + Cough Day and Night, Tylenol Sinus Congestion & Pain Nighttime, Tylenol with Codeine #2, Children's Triacting, Coricidin HBP Nighttime Multi-Symptom Cold, Night Time Multi Symptom Cold/Flu Relief, Mucinex Children's Cold, Cough & Sore Throat, Mucinex Fast-Max Cold, Flu & Sore Throat, Neocitran Non Drowsy Extra Strength Cold and Flu, IDA, Epidrin, Severe Allergy and Sinus Headache, Equate Allergy & Sinus Headache, Benadryl Allergy Plus Sinus Headache, Mucinex FreeFrom Cold, Flu & Congestion, Pamprin Cramp Menstrual Pain Relief, Cramp Tabs, Alka-Seltzer Plus Cold and Sinus, Sinutab Sinus Maximum Strength, Phenylgesic, Dolorex, Sine-Off Maximum Strength, Paracare, Febrol Solution, Childrens Panadol 1 - 5 Years, Feverall, Accidental First Aid Supplies Paracetamol, Panadol Childrens, Panamol, Doliprane Adultes, Redutemp, Expandox, Paracetamol EG, Paracetamol Ranbaxy, Paracetamol Sandoz Conseil, Paracetamol Teva, Elixsure Fever/Pain, Calpol Infant, Disprol Paracetamol, Calpol Fastmelts, Valorin, Miradol, Remedol, Panamax 240, Febridol, Cuprofen for Children, Amadol Paracetamol, Soul Pattinson Childrens Paracetamol Elixir, Arthriten, Goody's Headache Powders, Genace, Goody's Extra Strength, Arthriten Inflammatory Pain Formula, Vanquish, Apadaz, Bupap, Phrenilin Forte, Arcet, Isocet, Anolor 300, Endolor, Ide-cet, Sinapils, KneeRelief, Combiflex, Menstrual Relief Maximum Strength, Coricidin HBP Day & Night Multi-Symptom Cold, Tylenol Cold Multi-Symptom Nighttime, Alka-Seltzer Plus Maximum Strength Cold & Cough, Cold Multi-Symptom (Nighttime), Cough Formula M Multi-Symptom, BC Sinus Pain & Congestion, Dristan Cold Multi Symptom Formula, Comtrex Severe Cold & Sinus, HEB Allergy, Codimal, Kolephrin, Triaminicin, Sinutab Maximum Strength Caplets, G-Dologen, Drixoral Allergy Sinus, Drixoral Cold and Flu, Delsym Cough & Sore Throat, Vicks DayQuil HBP Cold & Flu, Diabetic Tussin Night Time Formula, Tylenol Cold & Cough Nighttime, Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula), Vicks Nyquil D Cold and Flu Nighttime Relief, Tylenol Severe Cold & Flu Night Time, NyCair, Mucinex Fast-Max Day Time Severe Cold, Non-Pseudo Cold Relief, Robitussin Severe Multi-Symptom Cough Cold + Flu, Adult Cold, Flu & Sore Throat, Tylenol Cold Severe Congestion Daytime, Flutabs, Theraflu Multi-Symptom Severe Cold with Lipton Flavors, Theraflu Warming Relief Daytime Severe Cold & Cough, Theraflu ExpressMax Daytime Severe Cold & Cough, Mucinex Nightshift Sinus, Daytime Cold, Nodolor, Migratine, Midchlor, Pain Reliever PM, Night Time Severe Cold and Cough, Sudafed PE Nighttime Cold, Theraflu ExpressMax Nighttime Severe Cold & Cough, Actifed Sinus Day and Night, Beechams All-in-One, Mucinex Sinus-Max Day & Night (Day), Sinus Congestion & Pain, Mucinex Sinus-Max Severe Congestion & Pain Maximum Strength, Verdrocet, Lorcet Plus, Lorcet 10/650, Maxidone, Zamicet, Percocet 10/650, Oxycet, Prolate, Midol Teen, Panadol Menstrual Relief, Menstrual PMS, Syncol, PMS Relief, Contac Cold + Flu (Day Formula), Sinus Congestion and Pain Daytime Cool Ice, Major-gesic, Apagesic, Duogesic, Relagesic, Acuflex, Darvocet A500, Trycet, Ornex, Ephed Plus, Sinutab Regular Strength, Tylenol Sinus Maximum Strength, Actifed Cold and Sinus, Frenadol, Tramapap, Terry White Chemists Paracetamol, Pharmacist Advice Paracetamol, Terry White Chemists Paracetamol Colourfree Children 5-12 Years, Tylenol Childrens Paracetamol, 7T Gummy ES Chewable Tablets, Conney Aspirin-Free, Priceline Paracetamol, Panadol Gel Caps, Pacimol Caplets, Pharmore Paracetamol, Tylophen, Basics Paracetamol, Genapap, Sigma Pain Relief, Pain Clear Paracetamol, Paraspen Drops, Panadol Colourfree Drops, Pharmacist Paracetamol Infant Drops, Pharmacist Paracetamol Infant Drops Colour Free, Bi-Lo Paracetamol, Pain-Eze Paracetamol Infant Drops Colour Free, Pharmaction Paracetamol, Biochemie Paracetamol, Healthsense Pain Relief Drops Children 1 Month to 2 Years, Black And Gold Paraceatmol, Pharmacist Advice Paracetamol Infant Drops, Black and Gold Paracetamol, Hexal Comfarol, Blooms the Chemist Paracetamol, Abenol, Paracetamol Soluble, Vitapap, Bristol Pharma Paracetamol, Sigma Paracetamol, Actimol Infant, ConRx Extra Strength, PediaCare Infants' Acetaminophen Fever Reducer/Pain Reliever, PediaCare Children's Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Childrens, PediaCare Smooth Melts Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Infants and Childrens Drops 1 Month-4 Years, Mapap Children's, Capital Chemist Paracetamol, Lemsip Cold and Flu Liquid Capsule, Children's Silapap, Pharmacy Health Own Name Paracetamol for Children, Febridol Infant Drops, Accidental Rapatabs, Chem Mart Chemadol Children 1 to 5 Years, Chem Mart Chemadol Colourfree, Chem Mart Chemadol Colourfree Children 5-12 Years, Chemists Own Chiildrens Paracetamol 5-12 Years, Lemsip Headcold, Chemists Own Childrens Paracetamol 1-5 Years, Chemists Own Paracetamol, Lemsip Original, Chemists Own Paracetamol Capseals, Chemists Own Paracetamol Pain & Fever 1 Month to 2 Years, Chemists Own Paracetamol Pain & Fever 1 to 5 Years, Chemists Own Paracetamol Pain and Fever 5 to 12 Years, A-Pak Laboratories Paediatric Analgesic Paracetamol, Chemplus Paracetamol, Chemworld Colourfree Childrens Paracetamol Double Strength 5-12 Years, Chemworld Colourfree Childrens Paracetamol Junior 1-5 Years, Chemworld Paracetamol, Chemworld Paracetamol Infant Colour Free, HyVee Health 8 Hour Pain Relief, Bydol, Chem Mart Chemadol, Leader 8 Hour Pain Reliever, Children's ElixSure, Little Fevers, Mapap Rapid Release Gelcaps, Benylin Sore Throat, Fawns & McAllan Paracetamol, Zee Unaspirin ES, Chem Mart Chemadol Colourfree Childrens 1-5 Years, Childrens Panadol 1 - 5 Years Colourfree, Childrens Panadol 5 - 12 Years Colourfree, Childrens Panadol 5 - 12 Years, Equaline Pain Relief, Help I Have A Headache, Febridol Clear Effervescent, Herron Paracetamol Tabsules, Panadol Rapid Handipak, Panadol Soluble, Paralgin Paracetamol Tabsules, Pharmacist Childrens Paracetamol Colourfree 1-5 Years, Pharmacist Childrens Paracetamol Colourfree 5-12 Years, Pharmacy Health Colour Free Childrens Paracetamol, Gold Cross Paracetamol, Tylenol Cold Sore Throat, Alpha First Aid Supplies Paracetamol, Guardian Childrens Paracetamol 5-12 Years, Guardian Paracetamol, Guardian Paracetamol Tabsules, Rex Paracetamol, Topcare Arthritis Pain Relief, Panadol Jr, Flu Strength Hot Lemon Powders, Paineze Paracetamol, Health Care Chemist Paracetamol Infant Drops Colour Free, Genebs, Herron Gold Paracetamol Tabsules, Herron Paracetamol, Tempra 2, Tempol, Herron Paracetamol Capseals, Tempra 3, Herron Paracetamol Capseals Handy Pack, Herron Paracetamol Handy Pack, Apra, Q-Nol, Claradol, Anacin Aspirin Free, Conacetol, Dolono, Coles Paracetamol, Genapap Extra Strength, Doliprane Sans Sucre, Dolitabs, Home Brand Paracetamol, Q-Pap Extra Strength, Dolko, ICN Paracetamol, Dolko Enfants, Dolotec, Vicks Formula 44 Custom Care Body Aches, James Dean Pharmacy Paracetamol, Pain-Eze, Efferalgan Pediatrique, Uniserts, Efferalganodis, Silapap Childrens, Dolono Infant, Geluprane, Paracetamol Arrow, Paracetamol Biogaran, Ed-APAP, St. Joseph Aspirin-Free, Country Chemists Paracetamol, Paracetamol Ivax, Liquiprin, Paracetamol Qualimed, Actamin, Adprin B, BF-Paradac, Paracetamol RPG, DG Health Pain Reliever, Tempra Quicklets, Tycolene, Lloydspharmacy Paracetamol Six Plus, Q-Pap, Paracetamol Winthrop, Triaminic Fever Reducer Pain Reliever, Lloydspharmacy Paracetamol Infant, Triaminic Infant Drops, Atasol Forte, Paralyoc, Tylenol Cool Caplet Extra Strength, Perfalgan Nourrissons Et Enfants, Acetaminophen-odan, Mapap Rapid Tabs, Jr. Tylenol, Mapap Extra Strength Rapid Burst, Infadrops, Tactinal, Disprol Soluble Paracetamol, Galpamol, Paldesic, Calpol Paediatric, Medinol Paediatric, Medinol Under 6, Alvedon, Infantaire Drops, Lemsip Pharmacy Non-Decongestant Formula, Aminofen, Calpol Six Plus, Masophen, Medinol Over 6, Nortemp Children's, Paracets, Anadin Paracetamol, Hedex, UN-Aspirin Extra Strength, Mandanol, Actimol Children's, Dakota Paracetamol, Umphamol, Paralgin, Parahexal, Mid West Products Numol Paracetamol, Parmol, Silapap Infants, Mapap Infant Drops, Mandanol Infant, Cetafen Extra, Mandanol 6+, Lemsip Childrens Cold & Flu, Fennings Childrens Cooling, Aurophen, Duatrol SR, Aldi Hedanol Paracetamol, Under Ten Care Infant, M-Pap, Alphapharm Paracetamol, No Frills Paracetamol, Tylenol Sore Throat Daytime, Nova Paracetamol, Mapap Meltaway, Numark Paracetamol, Amcal Childrens Paracetamol 1-5 Years, Nyal Paracetamol, Medi-Tabs, Amcal Childrens Paracetamol 5-12 Years, Orajel Maximum Strength Toothache, Amcal Paracetamol Pain Relief, Ordov Febrigesic Paracetamol, Topcare 8 Hour Pain Relief, Amcal Paracetamol Infant Drops 1 Month to 2 Years, Pain-Eze Paracetamol Infant Drops, Febridol Syrup for Children, Amcal Paracetamol Tabsules, Pharmacist Advice Colourfree Childrens Paracetamol Double Strength, Guardian Childrens Paracetamol, Pharmacist Formula Paracetamol, Pharmacist Formula Infants, Paraspen, RP Scherer Paracetamol, RP Scherer Paracetamol Liquid-Filled Capsules, Savings Paracetamol, Signature Range Paracetamol, Dymadon, Soul Pattinson Colour Free Paracetamol 1-5 Years, Soul Pattinson Colourfree Childrens Paracetamol, Panadol Gel Tabs, API Healthcare Coloufree Childrens Paracetamol, Soul Pattinson Paracetamol, API Healthcare Colourfree Childrens Paracetamol Double Strength, Soul Pattinson Paracetamol Clear Effervescent, Panadol Mini Caps, API Healthcare Paracetamol, Pharmacy Health Paracetamol, Terry White Chemists Colour Free Paracetamol 1-5 Years, Pharmacist Paracetamol, Terry White Chemists Colour Free Paracetamol Infant Drops, Goody's Body Pain, Excedrin Back & Body, Bayer Migraine Formula, Excedrin Menstrual Complete, ConRx Pain Reliever, Uricalm Intensive, Supac, Anacin Advanced Headache Formula, PainAid Extra-Strength Formula, CVS Extra Strength Headache Relief, Medique Pain-Off, Extra Pain Relief, Saleto, Levacet, Excedrin PM Headache, Rhinocaps, Staflex, Dristan Cold Maximum Strength, Phrenilin Forte (old formulation), Orbivan CF, Allzital, Triaprin, Sedapap, Dolgic, Marten-Tab, Prominol, Butex Forte, Promacet, Axocet, Alagesic LQ, Vtol LQ, Vanatol LQ, Pharmagesic, Anoquan, Two-Dyne, Tenake, Femcet, Tencet, Fiorpap, Repan, Dolmar, Ezol, G-1, Medigesic, Minotal, Mygracet, Pacaps, Alagesic, Americet, Zebutal, Nonbac, Vanatol S, Dolgic Plus, Dolgic LQ, Capacet, Orbivan, Phrenilin with Caffeine and Codeine, Excedrin Mild Headache, Valorin Extra, Excedrin Quick Tab, Hycomine Compound, Panlor DC, Panlor SS, Panlor, Dvorah, DHC Plus, Zerlor, Emagrin Forte (old formulation), Prodrin, MigraTen, Combiflex ES, Durabac Forte, Cafgesic Forte, Saleto-D, Flextra, Flextra Plus, Cafgesic, Durabac, Menstrual Relief Extra Strength, Menstrual Complete, Rid-A-Pain Compound, Ninjacof-A, 999 Cold Remedy Granular, Cotabflu, Colrex Compound, Colrex, Vicks NyQuil Cold & Flu Nighttime Relief (Alcohol Free), Tylenol Children’s Cold + Cough + Runny Nose, PediaCare Cough & Runny Nose Plus Acetaminophen, Flu HBP Maximum Strength, Mapap Cough & Sinus Formula, Vicks Formula 44 Custom Care Cough & Cold PM, Flu Relief BP, Coricidin HBP Multi-Symptom Cold (Night), Dimetapp Children's Multi-Symptom Cold & Flu (old formulation), Tylenol Children’s Cold + Flu, PediaCare Multi-Symptom Cold Plus Acetaminophen, PediaCare Flu Plus Acetaminophen, Tylenol Cold Head Congestion Nighttime, Comtrex Cold & Cough Day Night, Theraflu Nighttime Severe Cold & Cough Caplets, Tylenol Cold Head Congestion Day and Night, Comtrex Nighttime Cold & Cough, XL-3 Xtra Cold and Cough, Multi Symptom Cold (Night Formula), Multi Symptom Cold Relief, Alka-Seltzer Plus Maximum Strength Cold & Cough Liquid Gels, Alka-Seltzer Plus Severe Cold & Flu Formula Effervescent Tablets, Alka-Seltzer Plus Severe Sinus & Cold Hot Drink Mix, Dimetapp Children's Nighttime Flu, Theraflu Warming Relief Nighttime Multi-Symptom Cold Caplets, Triaminic Multi-Symptom Fever & Cold, Giltuss Multi-Symptom Cold & Flu, Giltuss Children's Multi-Symptom Cold & Flu, Comtrex Cold and Flu Maximum Strength, Comtrex Maximum Strength Cold Relief, Contac Severe Cold and Flu Maximum Stength, Theraflu Flu, Cold and Cough Powder, Comtrex Day and Night, Comtrex Cold and Flu Maximum Strength Tablet, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Contac Cold and Flu Maximum Strength, Allpanto-S, Co-Apap, Theracaps Multi-Symptom Cough & Cold Reliever, Alka-Seltzer Plus-D Multi-Symptom Sinus & Cold Liquid Gels, Triaminic Flu, Cough & Fever, Gelpirin-CCF, Contac Cold + Flu (Night Formula), Medicidin-D, ConRx Allergy Sinus, Allergy Pain Relief, Allergy Sinus PE Pain Relief, PX Allergy Sinus PE, Allergy Multi-Symptom, Robitussin Peak Cold Nighttime Nasal Relief, Relief-PE, Onset Forte, GNP Cold Relief Plus, Super Strength Sinadrin, Gendecon, Tylenol Allergy Multi-Symptom, Comtrex Flu Therapy, Tylenol Plus Children's Cold, Protid, Hybrid CF, Sine-Off Sinus/Cold, Tylenol Sinus Congestion and Pain Cool Burst Day Night, Dryphen, Covangesic, Norel SR, Trital SR, Rhinogesic, Alumadrine, Duadacin, Sinulin, Chlor-Trimeton Sinus, Comtrex Sinus and Nasal, Comtrex Nighttime Flu Therapy, Singlet, Simplet, Tricom, Comtrex Allergy Sinus, Allerest Sinus, Tylenol Allergy Sinus, Sinutab Ex-Strength, Comtrex Allergy Sinus Maximum Strength, Comtrex Allergy Sinus Night and Day, Allerest Headache Strength, Sinarest Extra Strength, Allergy Sinus Maximum Strength, Actifed Cold & Sinus, Tavist Allergy/Sinus/Headache, EZ III, Phenaphen with Codeine, Capital with Codeine Suspension, Aceta w/ Codeine, Cocet Plus, Capital w/Codeine, Cocet, Codrix, Phenflu CDX, Phenflu CD, Maxiflu CD, Maxiflu CDX, Dologen 325, Dologesic NF, Actidogesic, Drixoral Cold/Flu, Complete Sinus Relief, Sinadrin Plus, Drixoral Sinus, Hexaflu, Tylenol Children’s Cold + Cough + Sore Throat, PediaCare Cough & Sore Throat Plus Acetaminophen, Triaminic Cough & Sore Throat, Drixoral Cough/Sore Throat, Tylenol Cough and Sore Throat Daytime, Triaminic Softchews Cough & Sore Throat, Tylenol Cold & Cough Daytime, Topcare Cough and Sore Throat, Diabetic Tussin Night Time Cold & Flu, Mucinex Fast-Max Day Time Severe Cold and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Cold & Flu and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough and Night Time Cold & Flu Maximum Strength, Mucinex Children's Day Time & Night Time Multi-Symptom Cold Value Pack, Respa C&C, Respa C&C IR, Contac Day and Night Cold and Flu, Robitussin Peak Cold Nighttime Cold + Flu, Contac Cold + Flu (Night) Cooling Relief Liquid, Delsym Night Time Cough & Cold, Robitussin Cold + Flu (Nighttime), Vicks Nature Fusion Cold & Flu Nighttime Relief, Night Time Cold & Flu, Multi Symptom NiteTime, Alka-Seltzer Plus Severe Cold+Cough Night Liquid, Tylenol Cough & Sore Throat Nightime, Vicks NyQuil HBP Cold & Flu, Clear Cough PM Multi-Symptom, Mucinex Fast-Max Day & Night, Mucinex Sinus-Max Day & Night, Mucinex Fast-Max Day Severe Cold and Night Cold & Flu, Delsym Night Time Multi-Symptom, Tylenol Cold Multi-Symptom Nighttime Liquid, Alka-Seltzer Plus Night Cold Formula Liquid, Alka-Seltzer Plus Multi-Symptom Cold & Flu (Night Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough (Night Formula), Mucinex Fast-Max Night Time Cold & Flu Liquid Gels, Alka-Seltzer Plus Severe Sinus Congestion, Allergy & Cough Liquid Gels, Alka-Seltzer Plus Maximum Strength Night Cold & Flu Liquid Gels, Alka-Seltzer Plus Multi-Symptom Cold & Flu Day & Night Liquid Gels (Night Formula), Alka-Seltzer Plus Night Severe Cold+Flu Hot Drink Mix, All-Nite Cold, Multi-Symptom Nighttime, All-Nite Multi-Symptom Cold/Flu Relief, Mucinex Sinus-Max Pressure, Pain & Cough and Sinus-Max Clear & Cool Nasal Spray, Mucinex Children's Multi-Symptom Cold & Fever, Mucinex Children's FreeFrom Multi-Symptom Cold, Flu & Sore Throat, Delsym Cough+ Cold Day Time, Sudafed PE Head Congestion + Flu Severe, Tylenol Cold Multi-Symptom Severe, Tylenol Cold + Mucus Severe, Mucinex Fast-Max Cold, Flu & Sore Throat Liquid Gels, CounterAct Day, Tylenol Cold Head Congestion Severe (old formulation), Mucinex Fast-Max Severe Congestion & Cold, Decorel Forte Plus, Alka-Seltzer Plus Severe Cough, Mucus & Congestion Liquid Gels, Alka-Seltzer Plus Severe Sinus, Cold & Cough Liquid Gels, Phenflu DM, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Alka-Seltzer Plus Day Severe Cold+Flu Hot Drink Mix, Rompe Pecho MAX, Cold Head Congestion, Cold Multi-Symptom Severe, ConRx Cold, Mucus Relief Complete, Mucus Relief Plus, Cold & Cough PE Multi-Symptom, Suphedrine PE Cold & Cough, Sudafed PE Pressure+Pain+Cold, Tylenol Cough & Severe Congestion Daytime, Mucinex FreeFrom Cold & Flu Daytime and FreeFrom Cold & Flu Nighttime, Mucinex Fast-Max Severe Congestion & Cough and Nightshift Cold & Flu, Anatuss, Robitussin Cold Cough and Flu, Phlemgesic, Balminil Cough and Flu Sugar Free, Theraflu Max-D Severe Cold & Flu, Duraflu, Maxiflu DM, Tusnel-A, Mucinex Fast-Max DM Max and Nightshift Cold & Flu, Mucinex Fast-Max DM Max & Mucinex Nightshift Cold & Flu, Robitussin Peak Cold Daytime Cold + Flu, Contac Complete Cough, Cold & Flu Extra Strength, Tylenol Plus Children's Cold & Cough, Robitussin Cold + Flu (Daytime), Mapap Cold Formula, BC Cough & Cold, Little Colds Multi-Symptom, Vicks Nature Fusion Cold & Flu Multi-Symptom Relief, Comtrex Cold and Cough Maximum Strength, Day Relief PE, Vicks Dayquil Cold & Flu Symptom Relief Plus Vitamin C, Day Time Multi-Symptom Cold/Flu Relief, Mucinex Fast-Max Congestion & Headache, Alka-Seltzer Plus Severe Sinus Congestion & Cough Liquid Gels, Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels, Alka-Seltzer Plus Multi-Symptom Cold & Flu Day Liquid Gels, Cold Multi-Symptom (Daytime), Theraflu Warming Relief Daytime Multi-Symptom Cold Caplets, Tylenol Cold Head Congestion Daytime, Sudafed PE Pressure+Pain+Cough, Flu & Severe Cold & Cough Daytime Powder, Mucinex Nightshift Severe Cold and Flu, Mucinex Children's FreeFrom Multi-Symptom Cold & Flu Nighttime, Mucinex Nightshift Cold & Flu Clear & Cool, Mucinex Nightshift Sinus Clear & Cool, Comtrex Non Drowsy Liquigel, Theraflu Flu Cold & Cough, Tylenol Cold + Flu Multi-Action, Alka-Seltzer Plus Flu/Body, Comtrex Non-Drowsy, Contac Severe Cold and Flu Non Drowsy, Day Time Multi Symptom, Non-Drowsy Super Strength Contac Complete, Contact Cold and Sore Throat, Day Relief Cold and Flu, Tylenol Cold Non-Drowsy Gelcaps, Daytime Cold and Flu Relief, Daytime Non-Drowsy, Theraflu (pseudoephedrine) Daytime Severe Cold, Severe Cold Multi-Symptom, Migragesic IDA, LarkaDrin, Diacetazone, Migrazone, Isocom, Migrapap, Mitride, Migquin, Migrex, Alidrin, Iso-Acetazone, Migrin-A, Duradrin, Bayer Select Max Strength Night Time Pain, ConRx PM, Acetadryl, Night Time Pain, Unisom PM Pain, Genapap PM, Mapap PM, Counteract PM Extra Strength, Midol PM, Wal-Nadol PM Extra Strength, Excedrin PM, Headache Formula PM, Sominex Pain Relief Formula, Coricidin Night Time Cold Relief, Tylenol Sore Throat Nighttime, Pharbetol PM, Non-Aspirin PM Extra Strength, Acetaminophen PM Extra Strength, Aceta-Gesic, Tylenol Severe Allergy, Percogesic Extra Strength, Anacin PM Aspirin Free, Mucinex Sinus-Max Day and Night Maximum Strength, Dimetapp Children's Multi-Symptom Cold & Flu, Tylenol Plus Children's Cold & Allergy, Sudafed PE Severe Cold, Theraflu Warming Relief Nighttime Severe Cold & Cough, Delsym Cough+ Cold Night Time, Delsym Children’s Cough+ Cold Night Time, Mucinex Sinus-Max Night Time Congestion & Cough, Suphedrine PE Severe Cold, CounterAct Night, Robitussin Multi-Symptom Cold Night Time, Mucinex Children's Night Time Multi-Symptom Cold, Mucinex Sinus-Max Day & Night (Night), Theraflu Warming Relief Flu & Sore Throat, Benadryl Severe Allergy Plus Sinus Headache, CVS Allergy & Cold, Tylenol Allergy Multi-Symptom Nighttime, CVS Allergy & Sinus Headache, Children's Tylenol Plus Cold And Allergy, Robitussin Severe Multi-Symptom Cough Cold + Flu Nighttime, Theraflu Warming Relief Sinus & Cold, Theraflu ExpressMax Flu, Cough & Sore Throat, Theraflu Nighttime Multi-Symptom Severe Cold With Lipton Flavors, Benadryl Cold, Contac Day and Night Allergy, Sudafed Sinus Nighttime Plus Pain, Tylenol Allergy Complete NightTime, Benadryl Severe Allergy & Sinus Headache, Vicks QlearQuil Nighttime Sinus & Congestion, Alka-Seltzer Plus Severe Allergy Sinus Congestion & Headache, Vicks Sinex Nighttime, Tylenol Sinus NightTime, Tylenol Sinus Day/Night Convenience Pack, Tylenol Chest Congestion, Theraflu Flu & Chest Congestion, Comtrex Deep Chest Cold, Duratuss-A, LuSonex Plus, Mucinex Fast-Max Cold & Sinus, Mucinex Sinus-Max Pressure & Pain, Mucinex Sinus-Max Severe Congestion Relief, ConRx Sinus, Sudafed PE Head Congestion + Mucus, Histenol-Forte II, Theraflu Warming Relief Cold and Chest Congestion, Emagrin Forte, Mucinex Fast-Max Congestion and Headache Clear & Cool, Tylenol Cold Head Congestion Severe, Sudafed PE Triple Action, Coldonyl, Sudafed PE Pressure+Pain+Mucus, Mucinex Sinus-Max Day Time Severe Congestion Relief, Tylenol Sinus Severe Congestion Daytime, Sudafed Triple Action, Co-Gesic, Duocet, Duradyne DHC, Hydrogesic, Margesic H, T-Gesic, Zydone, Lorcet HD, Hy-Phen, Vicodin HP, Panacet, Stagesic, Xodol, Vanacet, Dolagesic, Hydrocet, Zyfrel, Zolvit, Dolacet, Theracodophen Low 90, Anolor DH5, Liquicet, Back Quell, Otis Clapp Back Quell, Roxilox, Percocet 2.5/325, Perloxx, Magnacet, Primlev, Xolox, Nalocet, Tylenol Women's Menstrual Relief, PainAid Premenstrual Formula, Backaid Max, Lurline PMS, Premsyn PMS, Menstrual Relief Multi-Symptom, PMS Formula Multi-Symptom, Talacen, Theraflu Cold & Sore Throat, Theraflu Flu & Sore Throat, Scot-Tussin Original, Theraflu Sinus & Cold, Tylenol Plus Children's Cold & Stuffy Nose, Suphedrine PE Sinus Headache, Vicks QlearQuil Daytime Sinus & Congestion, Robitussin Peak Cold Nasal Relief, Excedrin Sinus Headache, Dilotab 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Acetaminophen Levels and Effects while Breastfeeding

Summary of Use during Lactation

Acetaminophen is a good choice for analgesia, and fever reduction in nursing mothers. Amounts in milk are much less than doses usually given to infants. Adverse effects in breastfed infants appear to be rare.

Drug Levels

Maternal Levels. A single oral dose of 650 mg of acetaminophen was given to 12 nursing mothers who were 2 to 22 months postpartum. Peak milk levels of 10 to 15 mg/L occurred between 1 and 2 hours after the dose in all patients. Acetaminophen was undetectable (<0.5 mg/L) in all mothers 12 hours after the dose. The authors calculated that an infant who ingested 90 mL of breastmilk every 3 hours would receive an average of 0.88 mg of acetaminophen or 0.14% (range 0.04 to 0.23%) of the mother's absolute dosage.[1] Using data from this study, an infant would receive a maximum of about 2% of the maternal weight-adjusted dosage.

Three women took a single 500 mg dose of acetaminophen. Peak milk levels averaging 4.2 mg/L occurred within 2 hours after the dose.[2] Using data from this study, an infant would receive a maximum of about 3.6% of the maternal weight-adjusted dosage.

Four women who were 2 to 8 months postpartum were given a single 1 gram dose of acetaminophen. Milk was completely emptied from one breast every 30 minutes for 3 to 3.5 hours, with a final sample from the opposite breast. Peak milk levels occurred between 1 and 2.5 hours after the dose. The acetaminophen level in the breast that was sampled only once had a lower level than the breast sampled at half-hour intervals. The authors estimated that a breastfed infant would receive an average of 1.1% and a maximum of 1.8% of the maternal weight-adjusted dosage. This dose is about 0.5% of the lowest recommended infant dose of acetaminophen.[3]

Infant Levels. No acetaminophen was detected in the urine of 12 breastfed infants aged 2 to 22 months after maternal ingestion of 650 mg of acetaminophen.[4]

Urine was collected for 1 to 3.5 hours after nursing in 6 infants aged 2 to 6 days whose mothers received 1 to 2 grams of acetaminophen 2 to 4 hours before nursing their infant. Infants excreted an average of 401 mcg of acetaminophen and its metabolites in urine during the collection interval. These neonates excreted a greater percentage of drug as acetaminophen and much less as the sulfate metabolite than in an adult comparison population.[3]

Effects in Breastfed Infants

A maculopapular rash on the upper trunk and face of a 2-month-old infant was probably caused by acetaminophen in breastmilk. The rash occurred after 2 days of therapy in the mother at a dose of 1 gram at bedtime. It subsided when the drug was discontinued and recurred 2 weeks later after another acetaminophen dose of 1 gram was taken by the mother.[5]

Two papers report 14 women who breastfed after taking acetaminophen or its prodrug phenacetin with no adverse effects to their infants.[4,6]

In a telephone follow-up study, mothers reported no side effects among 43 infants exposed to acetaminophen in breastmilk.[7]

Two clinicians speculated that breastmilk exposure to acetaminophen during breastfeeding might be a risk factor for asthma and wheezing in the breastfed infants based on their personal observations.[8] However, these observations were uncontrolled and cannot be considered to be valid proof of an association.[9]

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Ibuprofen

References

1.
Berlin CM Jr, Yaffe SJ, Ragni M. Disposition of acetaminophen in milk, saliva and plasma of lactating women. Pediatr Pharmacol (New York). 1980;1:135–41. [PubMed: 7202185]
2.
Bitzén PO, Gustafsson B, Jostell KG, et al. Excretion of paracetamol in human breast milk. Eur J Clin Pharmacol. 1981;20:123–5. [PubMed: 7262173]
3.
Notarianni LJ, Oldham HG, Bennett PN. Passage of paracetamol into breast milk and its subsequent metabolism by the neonate. Br J Clin Pharmacol. 1987;24:63–7. [PMC free article: PMC1386281] [PubMed: 3620287]
4.
Berlin CM Jr, Yaffe SJ, Ragni M. Disposition of acetaminophen in milk, saliva and plasma of lactating women. Pediatr Pharmacol. 1980;1:135–41. [PubMed: 7202185]
5.
Matheson I, Lunde PKM, Notarianni L. Infant rash caused by paracetamol in breast milk? Pediatrics 1985;76:651-2. Letter. PMID: 2931668. [PubMed: 2931668]
6.
Findlay JW, DeAngelis RL, Kearney MF, et al. Analgesic drugs in breast milk and plasma. Clin Pharmacol Ther. 1981;29:625–33. [PubMed: 7214793]
7.
Ito S, Blajchman A, Stephenson M, et al. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. 1993;168:1393–9. [PubMed: 8498418]
8.
Verd S, Nadal-Amat J. Paracetamol and asthma and lactation. Acta Paediatr. 2011;100:e2–3. [PubMed: 21244486]
9.
Bakkeheim E, Carlsen KH, Lodrup Carlsen KC. Paracetamol exposure during breastfeeding and risk of allergic disease. Acta Paediatr. 2011;100:e3. [CrossRef]

Substance Identification

Substance Name

Acetaminophen

CAS Registry Number

103-90-2

Drug Class

Breast Feeding

Lactation

Analgesics, Non-Narcotic

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Further information

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