Duragesic Interactions
There are 634 drugs known to interact with Duragesic (fentanyl), along with 17 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 260 are major, 370 are moderate, and 4 are minor.
- View all 634 medications that may interact with Duragesic
- View Duragesic alcohol/food interactions (1)
- View Duragesic disease interactions (17)
Most frequently checked interactions
View interaction reports for Duragesic (fentanyl) and the medicines listed below.
- Ambien (zolpidem)
- aspirin
- Ativan (lorazepam)
- baclofen
- clonazepam
- Cymbalta (duloxetine)
- Dilaudid (hydromorphone)
- Flexeril (cyclobenzaprine)
- gabapentin
- Klonopin (clonazepam)
- Lasix (furosemide)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- metformin
- Neurontin (gabapentin)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- Phenergan (promethazine)
- prednisone
- Protonix (pantoprazole)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zanaflex (tizanidine)
- Zofran (ondansetron)
Duragesic alcohol/food interactions
There is 1 alcohol/food interaction with Duragesic (fentanyl).
Duragesic disease interactions
There are 17 disease interactions with Duragesic (fentanyl) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- fever
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
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More about Duragesic (fentanyl)
- Duragesic consumer information
- Compare alternatives
- Reviews (71)
- Latest FDA alerts (18)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.