Duragesic Interactions
There are 635 drugs known to interact with Duragesic (fentanyl), along with 17 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 259 are major, 372 are moderate, and 4 are minor.
- View all 635 medications that may interact with Duragesic
- View Duragesic alcohol/food interactions (1)
- View Duragesic disease interactions (17)
Most frequently checked interactions
View interaction reports for Duragesic (fentanyl) and the medicines listed below.
- Ambien (zolpidem)
- Ambien (zolpidem)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- Flexeril (cyclobenzaprine)
- gabapentin
- gabapentin
- Lasix (furosemide)
- Lasix (furosemide)
- lisinopril
- lisinopril
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Neurontin (gabapentin)
- Neurontin (gabapentin)
- Norco (acetaminophen / hydrocodone)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- omeprazole
- oxycodone
- oxycodone
- Protonix (pantoprazole)
- Protonix (pantoprazole)
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- trazodone
- trazodone
- Xanax (alprazolam)
- Xanax (alprazolam)
Duragesic alcohol/food interactions
There is 1 alcohol/food interaction with Duragesic (fentanyl).
Duragesic disease interactions
There are 17 disease interactions with Duragesic (fentanyl) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- fever
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
Report options
More about Duragesic (fentanyl)
- Duragesic consumer information
- Compare alternatives
- Reviews (71)
- Latest FDA alerts (18)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Ozempic
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Cymbalta
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Oxycodone
Oxycodone is an opioid analgesic used to treat moderate to severe pain; it has a high potential for ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Amitriptyline
Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions ...
Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.