Promethazine DM Interactions
There are 751 drugs known to interact with Promethazine DM (dextromethorphan/promethazine), along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 163 are major, 574 are moderate, and 14 are minor.
- View all 751 medications that may interact with Promethazine DM
- View Promethazine DM alcohol/food interactions (2)
- View Promethazine DM disease interactions (13)
Most frequently checked interactions
View interaction reports for Promethazine DM (dextromethorphan / promethazine) and the medicines listed below.
- albuterol
- amlodipine
- amoxicillin
- aspirin
- atorvastatin
- azithromycin
- Benadryl (diphenhydramine)
- benzonatate
- cyclobenzaprine
- doxycycline
- famotidine
- gabapentin
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- metformin
- montelukast
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- tizanidine
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Promethazine DM alcohol/food interactions
There are 2 alcohol/food interactions with Promethazine DM (dextromethorphan / promethazine).
Promethazine DM disease interactions
There are 13 disease interactions with Promethazine DM (dextromethorphan / promethazine) which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
Report options
More about Promethazine DM (dextromethorphan / promethazine)
- Promethazine DM consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (43)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.