Promethazine DM Interactions
There are 752 drugs known to interact with Promethazine DM (dextromethorphan/promethazine), along with 13 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 163 are major, 575 are moderate, and 14 are minor.
- View all 752 medications that may interact with Promethazine DM
- View Promethazine DM alcohol/food interactions (2)
- View Promethazine DM disease interactions (13)
Most frequently checked interactions
View interaction reports for Promethazine DM (dextromethorphan / promethazine) and the medicines listed below.
- albuterol
- amlodipine
- amoxicillin
- aspirin
- atorvastatin
- azithromycin
- Benadryl (diphenhydramine)
- benzonatate
- cyclobenzaprine
- doxycycline
- famotidine
- gabapentin
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- metformin
- montelukast
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- tizanidine
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Promethazine DM alcohol/food interactions
There are 2 alcohol/food interactions with Promethazine DM (dextromethorphan / promethazine).
Promethazine DM disease interactions
There are 13 disease interactions with Promethazine DM (dextromethorphan / promethazine) which include:
- acute alcohol intoxication
- CNS depression
- hematologic toxicity
- hypotension
- liver disease
- antidopaminergic effects 1
- asthma
- anticholinergic effects
- asthma/COPD
- breast cancer
- NMS
- seizure disorders
- antidopaminergic effects 2
Report options
More about Promethazine DM (dextromethorphan / promethazine)
- Promethazine DM consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (43)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Benzonatate
Benzonatate is a non-narcotic cough medicine used to relieve coughing. Includes benzonatate side ...
Loratadine
Loratadine is a non-drowsy antihistamine used to relieve allergy symptoms like sneezing, runny ...
Methylprednisolone
Methylprednisolone is used to treat conditions such as allergies, arthritis, lupus and ulcerative ...
Cetirizine
Cetirizine treats cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose ...
Montelukast
Montelukast is a daily oral medication used to prevent asthma attacks, exercise-induced ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.